Patents
[등록] 최정규, 이만희, 박진희, 정지희, 정자, 난자와 식물세포를 관찰할 수 있는 스마트폰용 현미경, 제 10-2774164 호, 등록 2025.02.24.
[등록] Won Ho Jhe, Sang Min An, Man Hee Lee, and Chung Man Kim, Rheometer, Patent No.: US 12,098,990 B2, Date of Patent: Sep. 24, 2024.
[PCT] Rheometer
[등록] Junhong Park, Manhee Lee, Atomic force microscope using artificial intelligence object recognition technology and operation method thereof, Patent No.: US 11,709,180 B2, Date of Patent: Jul. 25, 2023.
[등록] 이만희, 강성석, 박준홍, 인공지능 객체 인식 기술을 이용한 원자 힘 현미경 및 이의 동작 방법, 등록 2022.05.19 제 10-2401164.
[출원] 최정규, 이만희, 박진희, 정지희, 정자, 난자와 식물세포를 관찰할 수 있는 스마트폰용 현미경, 출원 2021.12.31 제 10-2021-0194008 호.
[PCT] Manhee Lee & Junhong Park, Autonomous operation of atomic force microscope by using machine learning-based object detection technique. PCT/KR2021/005882 (2021.05.11)
[등록] 제원호, 안상민, 김충만, 이만희, 리오미터, 등록 2021.05.10 제 10-2252266 호.
[출원] 이만희, 강성석, 박준홍, 인공지능 객체 인식 기술을 이용한 원자 힘 현미경 및 이의 동작 방법, 출원 2020.07.14 제 10-2020-0087092 호.
[출원] 제원호, 안상민, 김충만, 이만희, 리오미터, 출원 2020.02.12 제 10-2020-0016746 호.
[등록] 이만희, 제원호, 미소 부피 액체용 점성 측정 장치 및 방법, 등록 2019.08.09 제 10-2011569 호.
[출원] 이만희, 제원호, 미소 부피 액체용 점성 측정 장치 및 방법, 출원 2017.08.31 제 10-2017-0111182 호.
Transfers of Technology
진공장비 부품 국산화를 위한 전기로터 제작 기술, (주)다온, 2020.12.23.
수압 구동 방식 미세유체 장치를 이용한 저점도 유체 점성 측정 기술, (주)마이크로트, 2020.12.23.
Books
안상민 & 이만희, “나노 현미경 기초”, ISBN 978-89-93491-89-0, 2020.12.
Papers
2025
Q. D. Nguyen, G.-E. Jung, Y. Jeong, S. An, M. Lee, H. H. Cho, and S.-J. Cho, Calibration of cantilever via thermal motion measurement for quantitative lateral force microscopy. Submitted.
Hyunsung Park, Junhong Park, Dongwon Kim, Dongeun Kim, Wonho Jhe, Jong Chul Han, and Manhee Lee*, Deep learning-assisted 10-μL single droplet-based viscometry for human aqueous humor. Biosensors and Bioelectronics 284, 15, 117530 (2025). [Publication: Sep 15, 2025] IF =10.7 | 2.4% in Chemistry, Analytical (May 2025)
Gyungbin Ju†, Dongwon Kim†, Hyungil Lee, and Manhee Lee*, Linear algebraic characterization of particle concentration and size distribution, Colloid and Interface Science Communications 68, 100852 (2025). [Publication: Sep 1 2025]
Jaewon Shim, Manhee Lee* and Wonho Jhe*, Interfacial entanglement-induced time-dependent solidification of polymeric fluids. Physics of Fluids 37, 082051 (2025). [Publication: Aug 20, 2025] IF =4.3 | 6.1% in Physics, Fluids & Plasmas (Aug 2025)
Byungwook Park, Jeongmok Cho, Gangil Lee, Gyungbin Ju, Yunseo Jang, Daniel Eumine, and Manhee Lee*, Nonequilibrium electrical conductivity-induced particle aggregation in ceria slurry. Surfaces and Interfaces 63, 106339 (2025). [Publication: April 15 2025]
Sanghyun Bae, Gyungbin Ju, Yunseo Jang, Jeongmok Cho, Manhee Lee* and Daniel Eumine Suk*, Enhancing Filtration Efficiency via Nanofibrillation of Polypropylene Fibers for Advanced Slurry Depth Filters in Semiconductor Manufacturing. ECS Journal of Solid State Science and Technology 14, 024008 (2025). [Publication; Feb 27 2025]
2024
Jaewon Shim, Chungman Kim, Manhee Lee*, Sangmin An*, and Wonho Jhe*, Multiscale rheology from bulk to nano using a quartz tuning fork-atomic force microscope. Rev. Sci. Instrum. 95(10), 105104 (2024). [Published Online: 4 October 2024]
Do Gyeung Byeun†, Dongwon Kim†, Jin Hee Park†, Manhee Lee* and Jung Kyu Choi*, Embryonic development through in vitro fertilization using high-quality bovine sperm separated in a biomimetic cervix environment. Analyst 149(11), 3078-3084 (2024). [Publication: May 01 2024]
In-Seong Jo, Joon Suk Oh, Matthieu Soula, Manhee Lee, David Pine, Etienne Ducrot*, Gi-Ra Yi*, DNA-coated microspheres with base mismatches for stepwise programmed assembly, Chemistry of Materials, Chem. Mater. 36, 8, 3820–3828 (2024). [Publication: April 4, 2024]
2023
S. Kang†, J. Park†, and M. Lee*, Machine learning-enabled autonomous operation for atomic force microscopes, Rev. Sci. Instrum. 94(12), 123704 (2023).
D. Kwon, B. Park, G. Ju, D. Kim, H. Lee, J. S. Lee, E. Suk, H. Kwoun, Y. Jang, S. Bae and and M. Lee*, Effect of Ionic Strength on Particle Aggregation in Ceria Slurry, New Phys.: Sae Mulli 73(11), 920-924 (2023). [Publication: Nov 30 2023]
2022
M. Lee*, H. Choi, B. Kim, and J. Kim, Giant fluidic impedance of nanometer-sized water bridges: shear capillary force at the nanoscale, Phys. Rev. E 105, 065108 (2022). [Publication: June 17 2022]
S. An, M. Lee, B. Kim, and W. Jhe, Capillary grip-induced stick-slip motion, Nano Res. 15, 7384–7391 (2022).
B. E. Lee, B. J. Lee, K. J. Lee, M. Lee, Y. J. Lim, J. K. Choi, and B. Keum, A simple and efficient cryopreservation method for mouse small intestinal and colon organoids for regenerative medicine. Biochem. Biophys. Res. Commun. 595, 14-21 (2022).
G. Ju, K. Kim, Y. Han, H. Lee, and M. Lee*, Colloidal particle sizing based on optical theorem, New Phys.: Sae Mulli 72, 63-68 (2022). [Publication: Jan 28 2022]
2021
M. Lee et al., Viscous cervical environment-on-a-chip for selecting high-quality sperm from human semen. Biomedicines 9(10), 1439 (2021). [Publication: Oct 10 2021]
D. Kwon, D. Kim, Y. Bae, H. Choi, B. Kim, M. Choi, S. An, and M. Lee*, Mathematical extraction of mechanical characteristics from electrical signal of electrically-driven quartz tuning fork in vacuum, air, and liquid environments. J. Korean Phys. Soc. 79, 485–491 (2021). [Publication: Jun 18 2021]
S. Kim, Y. Lee, M. Lee, S. An, and S.-J. Cho, Quantitative visualization of the nanomechanical Young’s modulus of soft materials by atomic force microscopy. Nanomaterials 11, 1593 (2021).
H. Choe, D. Kim, M. Lee*, and M. Choi, Tip-substrate shear interaction in quartz tuning fork-based atomic force microscopy in air. New Phys.: Sae Mulli 71, 439 (2021). [Publication: May 31 2021]
S. An†, M. Lee†, and W. Jhe, Probing the shear viscoelasticity of a nanoscale ionic liquid meniscus. Phys. Chem. Chem. Phys. 23, 12387 (2021), †Equal contribution. [Publication: May 05 2021]
2020
M. Lee*, D. Kim, T.-Y. Heo, T. Park, W. Kim, D. Choi, H. Kim, and J. Kim, Universal inherent fluctuations in statistical counting of large particles in slurry used for semiconductor manufacturing. Sci. Rep. 10, 14731 (2020).
2019
M. Lee*, A Stochastic simulation of noise-induced flipping from buckling for a microcantilever. New Phys.: Sae Mulli 69, 771 (2019).
M. Lee*, B. Kim, S. An, and W. Jhe, Dynamic responses of electrically driven quartz tuning fork and qPlus sensor: a comprehensive electromechanical model for quartz tuning fork. Sensors 19, 2686 (2019).
M. Lee*, S. An, and W. Jhe, Theoretical study of buckling-based nonlinear transition near a static bifurcation point. Phys. Rev. E. 99, 052202 (2019).
Y. Yoo, S. Moon, Y. Jang, I. Park, H. Lee, and M. Lee*, A comprehensive investigation of depth filter functionality for a colloidal slurry used for semiconductor manufacturing process. IEEE Trans. Semicond. Manuf. 32, 134 (2019).
2018
S. An, B. Kim, S. Kwon, G. Moon, M. Lee and W. Jhe, Buckling-based non-linear mechanical sensor. Sensors 18, 2637 (2018).
M. Lee*, Theory of the noise spectral density for micro-cantilevers under resonant frequency control. New Phys.: Sae Mulli 68, 718 (2018).
M. Lee, S. An, and W. Jhe, Evaluating signal and noise spectral density of a qPlus sensor with an active feedback control. AIP Adv. 8, 055228 (2018).
S. An, B. Kim, S. Kwon, G. Moon, M. Lee, and W. Jhe, Bifurcation-enhanced ultrahigh sensitivity of a buckled cantilever. Proc. Natl. Acad. Sci. U.S.A. 115, 2884 (2018).
M. Lee*, S. An, and W. Jhe, Analytical study of noise spectral density in Q-controlled atomic force microscopy. J. Korean Phys. Soc. 72, 384 (2018).
~2017
M. Lee, B. Kim, Q. Kim, J. Hwang, S. An, and W. Jhe. Viscometry of single nanoliter-volume droplets using dynamic force spectroscopy. Phys. Chem. Chem. Phys. 18, 27684 (2016).
M. Lee, J. Hwang, B. Kim, S. An, and W. Jhe. Fluid-induced resonances in vibrational and Brownian dynamics of a shear oscillator. Curr. Appl. Phys. 16, 1459 (2016).
M. Lee, J. Hwang, J. Jahng, Q. Kim, H. Noh, S. An, and W. Jhe. Electrical tuning of mechanical characteristics in qPlus sensor: Active Q and resonance frequency control. J. Appl. Phys. 120, 74503 (2016).
B. Kim, S. Kwon, M. Lee, Q. Kim, S. An, and W. Jhe. Probing nonlinear rheology layer-by-layer in interfacial hydration water. Proc. Natl. Acad. Sci. U.S.A. 112, 15619 (2015).
M. Lee, B. Kim, J. Kim, and W. Jhe. Noncontact friction via capillary shear interaction at nanoscale. Nature Communications 6, 7359 (2015).
M. Lee, J. W. Collins, D. M. Aubrecht, R. A. Sperling, L. Solomon, J. Ha, G. Yi, D. A. Weitz, and V. N. Manoharan. Synchronized reinjection and coalescence of droplets in microfluidics. Lab on a Chip 14, 509 (2014).
S. An, K. Lee, B. Kim, H. Noh, J. Kim, S. Kwon, M. Lee, M. Hong, and W. Jhe. Nanopipette combined with the quartz tuning fork-atomic force microscopy for force spectroscopy/microscopy and liquid delivery-based nanofabrications. Rev. Sci. Instrum. 85, 033702 (2014).
B. Kim, Q. Kim, S. Kwon, S. An, K. Lee, M. Lee, and W. Jhe. Unified stress tensor of the hydration water layer. Phys. Rev. Lett. 111, 246102 (2013).
S. An, K. Lee, B. Kim, J. Kim, S. Kwon, Q. Kim, M. Lee, and W. Jhe. Compensation of stray capacitance of the quartz tuning fork for a quantitative force spectroscopy. Curr. Appl. Phys. 13, 1899 (2013).
S. An, J. Kim, K. Lee, B. Kim, M. Lee, and W. Jhe. Mechanical properties of the nanoscale molecular cluster of water meniscus by high-precision frequency modulation atomic force spectroscopy. Appl. Phys. Lett. 101, 053114 (2012).
S. An, C. Stambaugh, G. Kim, M. Lee, Y. Kim, K. Lee, and W. Jhe. Low-volume liquid delivery and nanolithography using a nanopipette combined with a quartz tuning fork-atomic force microscope. Nanoscale 4, 6493 (2012).
S. An, M. Hong, J. Kim, S. Kwon, K. Lee, M. Lee, and W. Jhe. Quartz tuning fork-based frequency modulation atomic force spectroscopy and microscopy with all digital phase-locked loop. Rev. Sci. Instrum. 83, 113705 (2012).
J. Jahng, M. Lee, C. Stambaugh, W. Bak, and W. Jhe. Active feedback cooling of massive electromechanical quartz resonators. Phys. Rev. A, 84, 022318 (2011).
M. Lee, B. Sung, N. Hashemi, and W. Jhe. Study of nanoscale water cluster by atomic force microscopy. Faraday Disc. 41, 415 (2009).
N. Hashemi, M. R. Paul, H. Dankowicz, M. Lee, and W. Jhe. The dissipated power in atomic force microscopy due to interactions with a capillary fluid layer. J. Appl. Phys. 104, 063518 (2008).
M. Lee, J. Jahng, K. Kim, and W. Jhe. Quantitative atomic force measurement with a quartz tuning fork. Appl. Phys. Lett. 91, 023117 (2007).
J. Jahng, M. Lee, H. Noh, Y. Seo, and W. Jhe. Active Q control in tuning-fork-based atomic force microscopy. Appl. Phys. Lett. 91, 023103 (2007).
M. Lee and W. Jhe. General theory of amplitude-modulation atomic force microscopy. Phys. Rev. Lett. 97, 036104 (2006).