3D bioprinting is a cutting edge technology for creating human tissues of customizable and complex shapes in scalable manner. 3D bioprinted products can be applicable from drug discovery, toxicology, to personalized regenerative therapy. The key to 3D bioprinting technology is in "Bio-ink" - a mixture of cells and biomaterials. Bio-ink needs to be printable, biocompatible, biodegradable, and biomimetic. In order to guide functional tissue formation, bio-ink needs to mimic tissue-specific microenvironment and provide essential biomechanical and biochemical cues. In our lab, we aim to develop novel bio-inks that are specific to different types of tissues in health and disease to support printing functional tissues.

In vitro human tissue models hold great promise for more accurately predicting safety and efficacy of newly developed drugs and cosmetics than conventional models. To apply this technology in industry, we need a platform that enables fabrication of human tissues and/or organoids in reproducible and scalable manner. We are committed to developing a high-throughput tissue/organoid platform using advanced biomaterials and stem cell engineering techniques.

The heart serves as a mechanical "pump" in our bodies. However, to date, there is no in vitro heart model capable of executing organ-level functions such as perfusion. In our lab, we are developing a self-perfusable heart model based on insights from the heart's developmental processes. The goal of this research is to create a self-perfusable heart model to more accurately predict drug responses in vitro.