Publications

2024

Soah Lee†, Alison S Vander Roest†, Cheavar A Blair†, Kerry Kao†, Samantha B Bremner†, Matthew C Childers†, Divya Pathak†, Paul Heinrich, Daniel Lee, Orlando Chirikian, Saffie E Mohran, Brock Roberts, Jacqueline E Smith, James W Jahng, David T Paik, Joseph C Wu, Ruwanthi N Gunawardane, Kathleen M Ruppel, David L Mack, Beth L Pruitt, Michael Regnier, Sean M Wu, James A Spudich, Daniel Bernstein, Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration, Proceedings of the National Academy of Sciences, 2024

Hoyeon Lee, Boyoung Kim, Jihye Yun, Jinseung Bae, Sungsu Park, Junseok Jeon, Hye Ryoun Jang, Jaecheol Lee, Soah Lee, PIV-MyoMonitor: an accessible particle image velocimetry-based software tool for advanced contractility assessment of cardiac organoids, Front. Bioeng. Biotechnol., 2024

Boyoung Kim, Jiyoon Kim, Soah Lee, Unleashing the Power of Undifferentiated Induced Pluripotent Stem Cell Bioprinting: Current Progress and Future Prospects, Int J Stem Cells, 2024

2023

Francisco X Galdos, Carissa Lee, Soah Lee, Sharon Paige, William Goodyer, Sidra Xu, Tahmina Samad, Gabriela V Escobar, Adrija Darsha, Aimee Beck, Rasmus O Bak, Matthew H Porteus, Sean M Wu, Combined lineage tracing and scRNA-seq reveals unexpected first heart field predominance of human iPSC differentiation, eLife, 2023

2022

Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan CP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system, Journal of Clinical Investigation, 2022

Galdos FX, Xu S, Goodyer WR, Duan L, Huang YV, Lee S, Zhu H, Lee C, Wei N, Lee D, Wu SM, devCellPy is a machine learning-enabled pipeline for automated annotation of complex multilayered single-cell transcriptomic data, Nature Communications, 2022

2021

Chirikian O, Goodyer WR, Dzilic E, Serpooshan V, Buikema JW, McKeithan W, Wu H, Li G, Lee S, Merk M, Galdos F, Beck A, Ribeiro AJ, Paige S, Mercola M, Wu JC, Pruitt BL, Wu SM, CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes, Scientific Reports, 2021

Maas RGC†, Lee S†, Harakalova M, Blok CJB, Goodyer WR, Hjortnaes J, Doevendans P, Laake L, Velden J, Asselbergs F, Wu JC, Sluijter J, Wu SM, Buikema J. Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes, Star Protocols. 2021 († equal contribution).

2020

Buikema JW†, Lee S†, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, ... , Sluijter JPG, Wu SM. Wnt Signaling and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Cardiomyocytes. Cell Stem Cell. 2020 († equal contribution, IF: 20.9).

Miao Y†, Tian L†, Martin M, Paige SL, Galdos FX, Li J, Klein A, Zhang H, Ma N, Wei Y, Stewart M, Lee S, …, Wu SM, Gu M, Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome, Cell Stem Cell, 2020 († equal contribution).

Paige S†, Galdos F†, Lee S†, Chin E†, Ranjbarvaziri S, Feyen D, Darsha A, Xu S, Ryan J, Beck A, ... , Wu SM. Patient-Specific Induced Pluripotent Stem Cells Implicate Intrinsic Impaired Contractility in Hypoplastic Left Heart Syndrome, Circulation. 2020 († equal contribution, IF: 23.1).

Lee S†, Yang H†, C. Chen†, Venkatraman S, Darsha A, Wu SM, Wu JC, Seeger T, Simple Lithography-free Single Cell Micropatterning Using Laser-cut Stencils, JoVE, 2020 († equal contribution).

Puluca N†, Durmus NG†, Lee S, Belbachir N, Galdos FX, Ogut G, Gupta R, Hirano KI, Krane M, Lange R, Wu JC, Wu SM, Demirci U, Levitating Cells to Sort the Fit and the Fat, Advanced Biosystems, 2020 († contributed equally).

2019

Lee S, Stanton AE, Tong X, Yang F. Hydrogels with Enhanced Protein Conjugation Efficiency Reveal Stiffness-induced YAP Localization in Stem Cells Depends on Biochemical Cues. Biomaterials. 2019 (IF: 10.3).

Puluca N, Lee S, Doppler S, Munsterer A, Dreben M, Krane M, Wu SM, Bioprinting Approaches to Engineering Vascularized 3D Cardiac Tissues. Current Cardiology Reports, 2019.

Stanton A, Tong X, Lee S, Yang F, Biochemical Ligand Density Regulates Yes-Associated Protein Translocation in Stem Cells through Cytoskeletal Tension and Integrins. ACS Appl. Mater. Interfaces, 2019.

2018

Seeger T, Shrestha R, Lam C, Chen C, McKeithan W, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, Ashley E, Yang F, Karakikes I, Wu JC, A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-mediated Decay. Circulation, 2018.

2017

Lee S†, Serpooshan V†, Tong X, Venkatraman S, Lee M, Lee J, Chirikian O, Wu JC, Wu SM, Yang F. Contractile Force Generation by 3D hiPSC-derived Cardiac Tissues is Enhanced by Rapid Establishment of Cellular Interconnection in Matrix with Muscle-mimicking Stiffness. Biomaterials. 2017 († equal contribution, IF: 10.3).

Serpooshan V†, Chen P†, Wu H, Lee S, Sharma A, Hu D, Venkatraman S, Ganesan A, Yang F, Wu JC, Demirci U, Wu SM, Bioacoustic-enabled Assembly of Human iPSC-derived Cardiomyocytes into 3D Cardiac Tissue. Biomaterials, 2017 († equal contribution).

~ 2016 

Lee S, Tong X, Han L, Behn A, Yang F, Aligned Microribbon-like Hydrogels for Guiding Three-dimensional Smooth Muscle Tissue Regeneration. J. Biomed Mater Res A, 2016 (Winner of 2016 Young Investigator Award of the Society for Biomaterials, IF: 3.2).

Lee S, Tong X, Yang F, Effect of Poly(ethylene glycol) Hydrogel Crosslinking Mechanism on Protein Release. Biomaterials Science, 2016 (accepted as cover, IF: 5.3).

Tong X, Lee S, Barapour L, Yang F, Long-Term Controlled Protein Release from Poly(Ethylene Glycol) Hydrogels by Modulating Mesh Size and Degradation. Macromolecular Bioscience, 2015.

Lee S, Tong X, Yang F, The Effects of Varying Poly(ethylene glycol) Hydrogel Crosslinking Density and the Crosslinking Mechanism on Protein Accumulation in Three-Dimensional Hydrogels. Acta Biomaterialia, 2014 (IF: 6.6).