Publications

Kakade AA, Gupta S, Johnson A, Varghese R, Adicherla H, Nagarkar-Jaiswal S# (2025). Inseparable/IER3IP1 are essential for cytokinesis in Drosophila neuroblast and human cells

Proc. Natl. Acad. Sci. U.S.A. 122 (39) e2415361122

Wang P, Sarkar S, Huan ZH, Zhang Z, Balasubramanian D, Jayaram N, Datta S, He R, Wu P, Chao P, Zhang Y, Washburn MP, Florens L, Nagarkar-Jaiswal S, Jaiswal M#, Man Mohan# (2024). DYRK1A interacts with Tuberous Sclerosis complex and promotes mTORC1 activity. 

eLife 12:RP88318

Cheramangalam RN, Anand T, Pandey P, Balasubramaniyan D, Varghese R, Singhal N, Nagarkar-Jaiswal S#, Jaiswal M# (2023) E2 ubiquitin conjugase Bendless is essential for PINK1-Park activity to regulate Mitofusin under mitochondrial stress. 

PLoS Genet 19(4): e1010493

J Nandan, Nagarkar-Jaiswal S# (2019). Insights into Human Neurodegeneration: Lessons Learnt from Drosophila, Methods for Creating Fly Models to Understand the Molecular Mechanisms Underlying Neurological Diseases 37-54

Manivannan SN, Pandey P and Nagarkar-Jaiswal S# (2019). Flip-flop Mediated Conditional Gene Inactivation in Drosophila. 

Bio-protocol 9(3): e3157

Ashley J, Sorrentino V, Nagarkar-Jaiswal S, Tan L, Xu S, Xiao Q, Zinn K, Carrillo RA (2019). Transsynaptic interactions between IgSF proteins DIP-α and Dpr10 are required for motor neuron targeting specificity in Drosophila. 

elife 2019 Feb 4;8. pii: e42690

Venkatasubramanian L, Guo Z, Xu S, Tan L, Xiao Q, Nagarkar-Jaiswal S, Mann RS (2019). Stereotyped terminal axon branching of leg motor neurons mediated by IgSF proteins DIP-α and Dpr10. 

elife 2019 Feb 4;8. pii: e42692

Cosmanescu F, Katsamba PS, Sergeeva AP, Ahlsen G, Patel SD, Brewer JJ, Tan L, Xu S, Xiao S, Nagarkar-Jaiswal S, Bellen HJ, Zipursky LS , Honig B, and Shapiro L (2018). Neuron-subtype-specific expression, interaction affinities, and specificity determinants of DIP/Dpr cell recognition proteins. 

Neuron 6, P1385-1400.E6

Tan KL, Haelterman NA, Kwartler CS, Regalado ES, Lee PT, Nagarkar-Jaiswal S, Guo DC, Duraine L, Wangler MF; University of Washington Center for Mendelian Genomics, Bamshad MJ, Nickerson DA, Lin G, Milewicz DM, Bellen HJ (2018) Ari-1 regulates myonuclear organization together with Parkin and is associated with aortic aneurysms. 

Developmental Cell 45:226-244

Nagarkar-Jaiswal S.#, Manivannan SN , Zuo Z., Bellen HJ# (2017). Flip-Flop, a facile, cell cycle-independent, conditional gene inactivation strategy differentially tagging wild-type and mutant cells. 

eLife 6:e26420 (# Co-corresponding authors)

Yoon WH, Sandoval H, Nagarkar-Jaiswal S, Jaiswal M, Yamamoto S, Haelterman N, Putluri N, Putluri V, Sreekumar A, Muzny DM, Tos T, Aksoy A, Donti T, Graham B, Ohno M, Nishi E, Wangler M, Karaca E, Lupski JR, Bellen HJ (2017). Loss of Nardilysin, a chaperone for a-Ketoglutarate Dehydrogenase, causes neurodegeneration in flies and humans and promotes mTORC1 activation. 

Neuron 93:115-131

Li T, Giagtzoglou N, Eberl DF, Nagarkar-Jaiswal S, Cai T, Godt D, Groves AK, Bellen HJ (2016). The E3 ligase Ubr3 regulates Usher syndrome and MYH9 disorder proteins in the auditory organs of Drosophila and mammals. 

eLife 5:e15258

Skinner SO*, Xu H*, Nagarkar-Jaiswal S, Freire PR, Zwaka TP, Golding I (2016). Single-cell analysis of transcription kinetics across the cell cycle. (*equal contribution)

eLife 5:e12175 

Carrillo CA*, Özkan E*, Menon KP*, Nagarkar-Jaiswal S, Jeon M, Bellen HJ, Garcia CK, Zinn K (2015). Control of synaptic connectivity in Drosophila by a network of IgSF surface proteins. (*equal contribution)

Cell 163:1770-1782 

Tan L, Zhang K, Pecot M, Nagarkar-Jaiswal S, Lee PT, McEwen J, Nern A, Xu S, Tadros W, Chen Z, Zinn K, Bellen HJ, Morey M, Zipursky SL (2015). Complementary Expression of Ig superfamily ligands and receptors in synaptic pairs in the Drosophila visual system. 

Cell 163:1770-1782

Nagarkar-Jaiswal S*, DeLuca S*, Lee PT, Lin WW, Pan H, Zuo Z, Lv Z, Spradling AC, Bellen HJ (2015). A genetic toolkit for tagging intronic MiMICs containing genes.  (*equal contribution)

eLife 4:e08469 

Tian X, Gala U, Zhang Y, Shang W, Nagarkar-Jaiswal S, di Ronza Alberto, Jaiswal M, Yamamoto S, Sandoval H, Duraine L, Sardiello M, Sillitoe RV, Venkatachalam K, Fan H, Bellen HJ, Tong C (2015) A voltage gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis. 

PLoS Biology 13:e1002103

Nagarkar-Jaiswal S, Lee PT, Campbell ME, Chen K, Anguiano-Zarate S, Cantu Gutierrez M, Busby T, Lin WW, He Y, Schulze KL, Booth BW, Evans-Holm M, Venken KJ, Levis RW, Spradling AC, Hoskins RA, Bellen HJ (2015) A library of MiMICs allows tagging of genes and reversible spatial and temporal knockdown of proteins in Drosophila. 

eLife 4:e05338

Urban E*, Nagarkar-Jaiswal S*, Lehner CF, Heidmann SK (2014) The Cohesin Subunit Rad21 Is Required for Synaptonemal Complex Maintenance, but Not Sister Chromatid Cohesion, during Drosophila Female Meiosis. (*equal contribution)

PLoS Genetics 10(8):e1004540

Herzog S, Nagarkar-Jaiswal S, Urban E, Riemer A, Fischer S, Heidmann SK (2013) Functional dissection of the Drosophila melanogaster condensin subunit Cap-G reveals its exclusive association with condensin I. 

PLoS Genetics 9(4):e1003463.