Welcome to the SNJ Lab 

Neural stem cells self-renew to maintain their pool, yet differentiate into enormous functionally and morphologically distinct neurons and glia. Proper regulation of self-renewal and differentiation has profound consequences in development and homeostasis. Decreased neurogenesis could lead to defects in brain development resulting in neurodevelopmental disorders like microcephaly, epilepsy and autism. On the other hand, an increase in self-renewal could lead to malignancies such as cancer. We are interested in identifying the mechanisms and the molecular players underlying neural stem cell self-renewal and differentiation. To study these processes, we use Drosophila developing brain and human neuronal stem cells as model systems. We utilize state of the art genome editing tools and a diverse set of cell and molecular biology approaches. 

Opportunities and openings:

We are currently looking for enthusiastic and motivated students to do PhD / Postdoc with us. For further enquiries about these positions, please write to sonalnj@ccmb.res.in