Past Research Highlights

Dr. Michael Watson (CVM Vice President) is a co-author on a recent publication, "A Lipid-Structured Model of Atherosclerosis with Macrophage Proliferation" in the Bulletin of Mathematical Biology. The study, co-authored with Keith L. Chambers and Mary R. Myerscough, suggests that a more proliferative plaque differs from an equivalent (defined as having the same lipid content and cell numbers) recruitment-dominant plaque in the way lipid is distributed amongst the macrophages. In addition, the study concludes that the macrophage lipid distribution of an equivalent proliferation-dominant plaque is less skewed and exhibits a local maximum near the endogenous lipid content.

You can find the Open-Access article here.

Dr. Vijay Rajagopal (CVM subgroup President) and Michael Pan (member of SMB subgroup) have submitted a preprint related to their recent work on "Energy-based Modelling of Single Actin Filament Polymerisation Using Bond Graphs." Drs.   Gawthrop,  Pan,  and Rajagopal use energy-based bond models to describe f actin chemomechanical transduction, and subsequently show its agreement to experimental data.

You can read the preprint here.