Publications

Representative journals 

2025 ~ 

• Tiep Tien Nguyen†, Nhu-Nam Nguyen†, Linh Nguyen†, Kim-Phuong Phan, Junhyeung Park, Jong-Hyuk Sung, Simmyung Yook, Hu-Lin Jiang, Jee-Heon Jeong*, "Off‑the‑shelf, engineered non-living stem cell strategy for advancing cellular therapies", Nature biomedical engineering, 202606

• Seung Un Seo, Seon Min Woo, Yongsoo Kwon, Shin Kim, Hyun-Shik Lee, Sang Hyun Kim, Kyoung-jin Min, Simmyung Yook, Taeg Kyu Kwon* "Cathepsin L deletion enhances sensitivity to anticancer drugs through Parkin-mediated ubiquitination of Bcl-xL and USP53-induced Survivin destabilization", CELL DEATH AND DIFFERENTIATION, 2026, Early Access

• Bao-Toan Dang†, Khang-Yen Pham†, Huyen Thi Thu Le, Thoa Thi Kim Nguyen, An Thi Thanh Vu, Anil Giri, Prabhat Shrestha, Taeg Kyu Kwon, Jee-Heon Jeong, Simmyung Yook*, "Bispecific Macrophage Nano-Engager Couples Dual Checkpoint Blockade with Stimulator of Interferon Genes Activation to Potentiate Antitumor Immunity", ACS Nano, 2026

• Khang-Yen Pham, Thu Huyen Le Thi, Anil Giri, Jongjun Park, Jong-Sun Kang, Taeg Kyu Kwon, Jee-Heon Jeong*, Simmyung Yook*, "GSH-responsive nanovaccine triggers immunogenic cell death and potent memory T cell immunity for durable, recurrence-free tumor eradication", Bioactive Materials, 2026, 64, 135-158

• Dinesh Chaudhary, Rabyya Kausar, Jeonghye Lee, Manju Shrestha, Junhyeung Park, Yu Seok Youn, Jong Oh Kim, Jae-Young Lee, Ju-Yeon Kim*, Simmyung Yook *, Jee-Heon Jeong*, "Bioengineered hybrid spheroids integrating mesenchymal stem cells and metformin-loaded microspheres for the treatment of sepsis-induced liver injury", Journal of Controlled Release, 2026, 393, 114798 

• An Thi Thanh Vu†, Prabhat Shrestha†, Thu-Huyen Le Thi, Anil Giri, Khang-Yen Pham, Thoa Thi Kim Nguyen, Jinkyung Cho, Seho Kweon, Na Kyeong Lee, In-Sun Hong, Taeg Kyu Kwon, Jong-Sun Kang, Jee-Heon Jeong, Simmyung Yook*, "Protein corona-guided delivery of dextran-PLGA NPs for enhanced dendritic cell uptake, maturation and improved cancer immunotherapy", Journal of Controlled Release, 2026, 392, 114733 

• Prabhat Shrestha†, Doyoon Lee†, Anil Giri, Thu-Huyen Le Thi, Simmyung Yook*, "Genomic landscapes and therapeutic perspectives of cancer stem cells in the tumor microenvironment", JOURNAL OF PHARMACEUTICAL INVESTIGATION, 2025

• Bao-Toan Dang, Khang-Yen Pham, Ai-Han Nguyen, Jongjun Park, Taeg Kyu Kwon, Jong-Sun Kang, Jee-Heon Jeong, Simmyung Yook*, "Engineering Nanoparticles to Modulate Extracellular Matrix and Immune Components of the Tumor Microenvironment in Cancer Immunotherapy", BIOMATERIALS RESEARCH, 2025, 29, 0289

• Prakash Shrestha†, Shiva Pathak†, Dinesh Chaudhary†, Shobha Regmi, Manju Shrestha, Pawan Kumar Raut, Ju-Yeon Kim, Gorka Orive, Ha Rin Kim, Na Kyeong Lee, Seho Kweon, Jooho Park, Jeong Uk Choi, Simmyung Yook*, Jee-Heon Jeong*,"PEGylation-based surface engineering of islets with microparticles co-delivery for enhanced engraftment in streptozocin-induced hyperglycemic murine model", CHEMICAL ENGINEERING JOURNAL, 2025, 521, 166657

• Manju Shrestha†, Yun-Seo Kil†, Yunju Jo, Simmyung Yook, Ki Hyun Kim, Dongryeol Ryu*, Joo-Won Nam*, Jee-Heon Jeong*, "Comparative metabolomic and transcriptomic analysis of 2D and 3D mesenchymal stem cell cultures for improved therapeutic applications", BRITISH JOURNAL OF PHARMACOLOGY, 2025, Early Access

• Anil Giri, Yulim Shin, Jin Ha, Siyeon Chae, Prabhat Shrestha, Khang-Yen Pham, Taeg Kyu Kwon, Jong Ho Park, Jee-Heon Jeong, Na Kyeong Lee*, Simmyung Yook*, "Design of cathepsin-sensitive linkers for tumor-selective bioconjugate drug delivery", Journal of Controlled Release, 2025, 387, 114197

• Seonghun Lee†, Junhyeung Park†, Simmyung Yook*, Jee‑Heon Jeong*, "Layer‑by‑layer coating of drug‑loaded microspheres on silicone surfaces for biomedical applications", MACROMOLECULAR RESEARCH, 2025, 33(11),1479-1488

• Manju Shrestha, Tiep Tien Nguyen, Junhyeung Park, Dinesh Chaudhary, Rabyya Kausar, Yu Seok Youn, Ji Hoon Jeong, Jung Heon Lee, Sei Won Lee, Hye Yun Park, Simmyung Yook*, Jee-Heon Jeong*, "Surface-Engineering of Pancreatic Islets with ChitosanMicroparticles to Inhibit IBMIR in Islet Xenotransplantation", Small, 2025, 21(38), e03470

• Anil Giri, In-Sun Hong, Taeg Kyu Kwon, Jong-Sun Kang, Jee-Heon Jeong, Seho Kweon*, Simmyung Yook*, "Exploring therapeutic and diagnostic potential of cysteine cathepsin as targets for cancer therapy with nanomedicine", International Journal of Biological Macromolecules, 2025, 315 (part1), 144324

• Tiep Tien Nguyen†, Trang Nu Huyen Le†, Nhu-Nam Nguyen, Simmyung Yook, Dongryeol Ryu, Gorka Orive, Youngdae Gwon*, Jong-Hyuk Sung*, Jee-Heon Jeong*, "Low-dose rapamycin microdepots promote hair regrowth via autophagy modulation", Journal of Pharmaceutical Investigation, 2025, 56(2), 357-366

• Samjhana Shrestha†, Anil Giri†, Prabhat Shrestha, Seho Kweon, In-Sun Hong, Taeg Kyu Kwon, Jong-Sun Kang , Jee-Heon Jeong, Ha Rin Kim*, Simmyung Yook*, "CD44-targeted nanoparticles for remodeling the tumor microenvironment in a 3D macrophage-embedded ovarian cancer model with stem cell-like features", International Journal of Pharmaceutics, 2025, 674, 125483

• Manju Shrestha, Tiep Tien Nguyen, Rabyya Kausar, Dinesh Chaudhary, Ines Ferdiana Puspitasari, Hu-Lin Jiang*, Hyung-Sik Kim*,  Simmyung Yook*, Jee-Heon Jeong*, "Enhancing hair regrowth using rapamycin-primed mesenchymal stem cell-derived exosomes", Theranostics, 2025, 15(14), 6938-6956

• Khang-Yen Pham, Shristi Khanal, Ganesh Bohara , Nikesh Rimal, Sang-Hoon Song, Thoa  Thi  Kim  Nguyen, In-Sun  Hong, Jinkyung  Cho, Jong-Sun  Kang, Sooyeun  Lee*, DongYoung  Choi*, Simmyung  Yook*,  “HDAC6  inhibitor-loaded  brain-targeted  nanocarrier-mediated  neuroprotection  in  methamphetamine-driven  Parkinson's  disease”.  Redox  Biology, 2025, 79, 103457

• Thoa  Thi  Kim  Nguyen†, Seon  Min  Woo†, Seung  Un  Seo, Asmita  Banstola, Haesoo  Kim, Ramesh Duwa, An Thi Thanh Vu, In-Sun Hong, Taeg Kyu Kwon*, Simmyung Yook*,  “Enhanced  anticancer  efficacy  of  TRAIL-conjugated  and  odanacatib-loaded  PLGA  nanoparticles in TRAIL resistant cancer”. Biomaterials 2025, 312, 122733

2023 ~ 2024

• Ramesh Duwa, Jinsol Choi, Prabhat Shrestha, Thoa Thi Kim Nguyen, Lyndon D. Bastatas,  Youngdae Gwon, Soyeun Park*, Jee-Heon Jeong*, Simmyung Yook*, “Strengthened binding  affinity of bispecific antibody nanoplatforms improved the anti-tumor efficacy”. Chemical Engineering Journal, 2024, 494, 153128 

• Bao-Toan Nguyen Dang, Ramesh Duwa, Sooyeun Lee, Taeg Kyu Kwon, Jae-Hoon Chang, Jee-Heon Jeong*, Simmyung Yook*, "Targeting tumor-associated macrophages with mannosylated nanotherapeutics delivering TLR7/8 agonist enhances cancer immunotherapy", Journal of Controlled Release, 2024, 372, 587-608

• Bao-Toan Nguyen Dang, Taeg Kyu Kwon, Sooyeun Lee, Jee-Heon Jeong*, Simmyung Yook*, "Nanoparticle-based immunoengineering strategies for enhancing cancer immunotherapy" Journal of Controlled Release, 2024, 365, 773-800.

• Prabhat Shrestha, Ramesh Duwa, Sooyeun Lee, Taeg Kyu Kwon, Jee-Heon Jeong*, Simmyung Yook*, "ROS-responsive thioketal nanoparticles delivering system for targeted ulcerative colitis therapy with potent HDAC6 inhibitor, tubastatin A" European Journal of Pharmaceutical Sciences, 2024, 201, 106856.

• Seul Gi Lee†, Seon Min Woo†, Seung Un Seo, Chan-Hyeong Lee, Moon-Chang Baek, Se Hwan Jang, Zee Yong Park, Simmyung Yook, Ju-Ock Nam, Taeg Kyu Kwon*, "Cathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling". Experimental & Molecular Medicine, 2024, 56(2), 383-394.

• Seul Gi Lee, Seon Min Woo, Seung Un Seo, Hyun Shik Lee, Sang Hyun Kim, Young-Chae Chang, Hyo Je Cho, Simmyung Yook, Ju-Ock Nam, Taeg Kyu Kwon* "Non-canonical deubiquitination of OTUB1 induces IFNγ-mediated cell cycle arrest via regulation of p27 stability" Oncogene, 2024, 43(24), 1852-1860.

• Shobha Regmi, Shiva Pathak, Dinesh Chaudhary, Jong Oh Kim, Joo‑Won Nam, Hyung‑Sik Kim, Hu‑Lin Jiang, Dongryeol Ryu, Jong‑Hyuk Sung*, Simmyung Yook*, Jee‑Heon Jeong*  "Endogenous stem cell mobilization and localized immunosuppression synergistically ameliorate DSS-induced Colitis in mice" Stem Cell Research & Therapy, 2024, 15(1), 167.

• Tiep Tien Nguyen†, Yun-Seo Kil†, Jong-Hyuk Sung, Yu Seok Youn, Ji Hoon Jeong, Jung Heon Lee, Hu-Lin Jiang, Simmyung Yook*, Joo-Won Nam*, Jee-Heon Jeong* "Fabrication of stem cell heterospheroids with sustained-release chitosan and poly (lactic-co-glycolic acid) microspheres to guide cell fate toward chondrogenic differentiation". International Journal of Biological Macromolecules, 2024, 263(Part 2), 130356.

• Prakash Shrestha†, Shiva Pathak†, Shobha Regmi, Yu Seok Youn, Ji Hoon Jeong, Jung Heon Lee, Dongryeol Ryu, Simmyung Yook, Youngdae Gwon, Jeong Uk Choi*, Hu-Lin Jiang*, Ju-Yeon Kim*, Jee-Heon Jeong* "Catechol-modified stabilizer facilitates impulsive ligand functionalization of particulates and membrane modification of cells" Journal of Drug Delivery Science and Technology, 2024, 101(Part A), 106161.

• Manoj Kumar Baniya†, Ramesh Duwa†, Prabhat Shrestha, Jae-Hoon Chang, Kyung-Soo Chun*, Simmyung Yook* "AICAR-loaded and panitumumab conjugated nanoparticles downregulate the expression of PD-L1 and enhance antitumor responses against ovarian cancer through the AMPK/STAT3 axis". Journal of Pharmaceutical Investigation, 2024, 55, 283-302.

• Asmita Banstola, Mahesh Pandit, Ramesh Duwa, Jae-Hoon Chang, Jee-Heon Jeong*, Simmyung Yook*, "Reactive oxygen species‐responsive dual‐targeted nanosystem promoted immunogenic cell death against breast cancer". Bioengineering & Translational Medicine, 2023, 8(5), e10379.

• Thoa Thi Kim Nguyen, Khang-Yen Pham*, Simmyung Yook* "Engineered therapeutic proteins for sustained-release drug delivery systems" Acta Biomaterialia, 2023, 171, 131-154.

• Fakhrossadat Emami†, Ramesh Duwa†, Asmita Banstola, Seon Min Woo, Taeg Kyu Kwon, Simmyung Yook* "Dual receptor specific nanoparticles targeting EGFR and PD-L1 for enhanced delivery of docetaxel in cancer therapy" Biomedicine & Pharmacotherapy, 2023, 165, 115023.

• Dinesh Chaudhary, Tiep Tien Nguyen, Simmyung Yook*, Jee-Heon Jeong* "Advances in alginate encapsulation of pancreatic islets for immunoprotection in type 1 diabetes" Journal of Pharmaceutical Investigation, 2023, 53(5), 601-626.

• Tiep Tien Nguyen, Mai Thi Phuong, Manju Shrestha, Junhyeung Park, Pham Le Minh, Jong Oh Kim, Hyukjae Choi, Joo-Won Nam, Hu-Lin Jiang, Hyung-Sik Kim, Jee-Heon Jeong,* Jun-Beom Park,* Simmyung Yook*, "Scalable and uniform fabrication of dexamethasone-eluting depot-engineered stem cell spheroids as a microtissue construct to target bone regeneration" ACS applied materials & interfaces, 2023, 15(22), 26373-26384.

• Phuong Le Tran, Tung Thanh Pham, Han Sin Lee, Soojung Hahn, Jeong Uk Choi, Jae Hyeon Kim, Hu-Lin Jiang, Simmyung Yook*, Jee-Heon Jeong*, "Magnetic resonance imaging of pancreatic islets using tissue–adhesive particles containing iron oxide nanoparticles" Journal of Controlled Release, 2023, 364, 37-45.

2021 ~ 2022

• Ramesh Duwa†, Ram Hari Pokhrel†, Asmita Banstola, Mahesh Pandit, Prakash Shrestha, Jee-Heon Jeong*, Jae-Hoon Chang*, Simmyung Yook*, "T-cell engaging poly (lactic-co-glycolic acid) nanoparticles as a modular platform to induce a potent cytotoxic immunogenic response against PD-L1 overexpressing cancer". Biomaterials, 2022, 291, 121911.

• Prabhat Shrestha, Nikita Katila, Sooyeun Lee, Ji Hae Seo, Jee-Heon Jeong*, Simmyung Yook*, "Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies." Biomedicine & Pharmacotherapy, 2022, 154, 113591.

• Tiep Tien Nguyen, Duc-Vinh Pham, Junhyeung Park, Cao Dai Phung, Mahesh Raj Nepal, Mahesh Pandit, Manju Shrestha, Youlim Son, Mili Joshi, Tae Cheon Jeong, Pil-Hoon Park, Dong-Young Choi, Jae-Hoon Chang, Ju-Hyun Kim, Jae-Ryong Kim, Il-Kug Kim, Chul Soon Yong, Jong Oh Kim, Jong-Hyuk Sung, Hu-Lin Jiang, Hyung-Sik Kim, Simmyung Yook*, Jee-Heon Jeong*, "Engineering of hybrid spheroids of mesenchymal stem cells and drug depots for immunomodulating effect in islet xenotransplantation" Science Advances, 8(34), eabn8614.

• Samjhana Shrestha, Asmita Banstola, Jee-Heon Jeong, Ji Hae Seo, Simmyung Yook*, "Targeting Cancer Stem Cells: Therapeutic and diagnostic strategies by the virtue of nanoparticles", Journal of Controlled Release, 2022, 348, 518-536.

• Nikita Katila†, Ramesh Duwa†, Sunil Bhurtel, Shristi Khanal, Srijan Maharjan, Jee-Heon Jeong, Sooyeun Lee*, Dong-Young Choi*, Simmyung Yook*, "Enhancement of blood–brain barrier penetration and the neuroprotective effect of resveratrol" Journal of Controlled Release, 2022, 346, 1-19.

• Mahsa Keihan Shokooh†, Fakhrossadat Emami†, Ramesh Duwa, Jee-Heon Jeong*, Simmyung Yook*, "Triple-negative breast cancer treatment meets nanoparticles: Current status and future direction", Journal of Drug Delivery Science and Technology, 2022, 71, 103274.

• Fakhrossadat Emami†, Asmita Banstola†, Jee-Heon Jeong*, Simmyung Yook*, "Cetuximab-anchored gold nanorod mediated photothermal ablation of breast cancer cell in spheroid model embedded with tumor associated macrophage", Journal of Industrial and Engineering Chemistry, 2022, 106, 177-188.

• Prakash Shrestha†, Shiva Pathak†, Shobha Regmi, Kannan Badri Narayanan, Tiep Tien Nguyen, Simmyung Yook*, Jong Oh Kim*, Jee-Heon Jeong*, "Curcumin-laden ECM-mimicking microfibers assemble with mesenchymal stem cells to generate heterospheroids and enhance cell viability and function". Journal of Industrial and Engineering Chemistry, 2022, 115, 500-509.

• Asmita Banstola, Kishwor Poudel, Jong Oh Kim, Jee-Heon Jeong*, Simmyung Yook*, "Recent progress in stimuli-responsive nanosystems for inducing immunogenic cell death",  Journal of Controlled Release, 2021, 337, 505-520.

• Tiep Tien Nguyen, Cao Dai Phung, Jong Oh Kim, Chul Soon Yong, Jae-Ryong Kim, Simmyung Yook*, Jee-Heon Jeong*, "The impact of locally-delivered tacrolimus-releasing microspheres and polyethylene glycol-based islet surface modification on xenogeneic islet survival", Journal of Controlled Release, 2021, 336, 274-284.

• Tung Thanh Pham, Phuong Le Tran, Cao Dai Phung, Hanh Thuy Nguyen, Canh Hung Nguyen, Chul Soon Yong, Jong Oh Kim, Simmyung Yook*, Jee-Heon Jeong*, "Surface‐Triggered In Situ Gelation for Tunable Conformal Hydrogel Coating of Therapeutic Cells and Biomedical Devices", Advanced Functional Materials, 2021, 31(21), 2010169.

• Ramesh Duwa, Jee-Heon Jeong*, Simmyung Yook*, "Development of immunotherapy and nanoparticles-based strategies for the treatment of Parkinson’s disease", Journal of Pharmaceutical Investigation, 2021, 51, 465-481.

• Asmita Banstola, Kishwor Poudel, Shiva Pathak, Prakash Shrestha, Jong Oh Kim, Jee-Heon Jeong*, Simmyung Yook*, "Hypoxia-mediated ROS amplification triggers mitochondria-mediated apoptotic cell death via PD-L1/ROS-responsive, dual-targeted, drug-laden thioketal nanoparticles", ACS applied materials & interfaces, 2021, 13(19), 22955-22969.

• Shobha Regmi†, Yoojin Seo†, Ji-Su Ahn†, Shiva Pathak, Suman Acharya, Tiep Tien Nguyen, Simmyung Yook, Jong-Hyuk Sung, Jun-Beom Park, Jong Oh Kim, Chul Soon Young, Hyung-Sik Kim*, Jee-Heon Jeong*,  "Heterospheroid formation improves therapeutic efficacy of mesenchymal stem cells in murine colitis through immunomodulation and epithelial regeneration", Biomaterials, 2021, 271, 120752.

• Ramesh Duwa, Jee-Heon Jeong*, Simmyung Yook*, "Immunotherapeutic strategies for the treatment of ovarian cancer: current status and future direction", Journal of Industrial and Engineering Chemistry, 2021, 94, 62-77.

• Mahsa Keihan Shokooh, Fakhrossadat Emami, Jee-Heon Jeong*, Simmyung Yook*, "Bio-inspired and smart nanoparticles for triple negative breast cancer microenvironment. Pharmaceutics, 2021, 13(2), 287.

• Asmita Banstola, Kishwor Poudel Bachelor, Fakhrossadat Emami, Sae Kwang Ku, Jee-Heon Jeong, Jong Oh Kim*, Simmyung Yook*, "Localized therapy using anti-PD-L1 anchored and NIR-responsive hollow gold nanoshell (HGNS) loaded with doxorubicin (DOX) for the treatment of locally advanced melanoma", Nanomedicine: Nanotechnology, Biology and Medicine, 2021, 33, 102349.

• Shiva Pathak, Suman Acharya, Shobha Regmi, Prakash Shrestha, Zhiwei You, Young Kyung Bae, Min Hui Park, Simmyung Yook, Jae-Ryong Kim, So Young Park, Daewon Jeong, Chul Soon Yong, Jong Oh Kim, Jae Hoon Chang*, Jee-Heon Jeong*, "Particulate‐Based Single‐Dose Local Immunosuppressive Regimen for Inducing Tolerogenic Dendritic Cells in Xenogeneic Islet Transplantation", Advanced Healthcare Materials, 2021, 10(2), 2001157.

• Manju Shrestha, Tiep Tien Nguyen, Jooho Park, Jeong Uk Choi, Simmyung Yook*, Jee-Heon Jeong*, "Immunomodulation effect of mesenchymal stem cells in islet transplantation", Biomedicine & Pharmacotherapy, 2021, 142, 112042.

• Fakhrossadat Emami, Shiva Pathak, Tiep Tien Nguyen, Prakash Shrestha, Srijan Maharjan, Jong Oh Kim, Jee-Heon Jeong*, Simmyung Yook*, "Photoimmunotherapy with cetuximab-conjugated gold nanorods reduces drug resistance in triple negative breast cancer spheroids with enhanced infiltration of tumor-associated macrophages", Journal of Controlled Release, 2021, 329, 645-664.

2019 ~ 2020

• Asmita Banstola, Ramesh Duwa, Fakhrosaddat Emami, Jee-Heon Jeong, Simmyung Yook*, "Enhanced caspase-mediated abrogation of autophagy by temozolomide-loaded and panitumumab-conjugated poly (lactic-co-glycolic acid) nanoparticles in epidermal growth factor receptor overexpressing glioblastoma cells", Molecular pharmaceutics, 2020, 17(11), 4386-4400.

• Asmita Banstola, Jee-Heon Jeong*, Simmyung Yook*, "Immunoadjuvants for cancer immunotherapy: A review of recent developments", Acta biomaterialia, 2020, 114, 16-30.

• Ramesh Duwa, Asmita Banstola, Fakhrossadat Emami, Jee-Heon Jeong*, Sooyeun Lee, Simmyung Yook*, "Cetuximab conjugated temozolomide-loaded poly (lactic-co-glycolic acid) nanoparticles for targeted nanomedicine in EGFR overexpressing cancer cells", Journal of drug delivery science and technology, 2020, 60, 101928.

• Shiva Pathak, Shobha Regmi, Mahesh Raj Nepal, Prakash Shrestha, Jeong Uk Choi*, Simmyung Yook*, Jee-Heon Jeong*, "Single-dose intraperitoneal delivery of FK506-encapsulated polymeric microspheres for the alleviation of murine colitis", Journal of Industrial and Engineering Chemistry, 2020, 91, 121-128.

• Tiep Tien Nguyen, Fakhrossadat Emami, Simmyung Yook*, Hanh Thuy Nguyen, Tung Thanh Pham, Shiva Pathak, Shobha Regmi, Jong Oh. Kim, Chul Soon Yong, Jae-Ryong Kim, Jee-Heon Jeong*, "Local release of NECA (5′-(N-ethylcarboxamido) adenosine) from implantable polymeric sheets for enhanced islet revascularization in extrahepatic transplantation site", Journal of Controlled Release, 2020, 321, 509-518.

• Simmyung Yook†, Zhongli Cai†, Jenny Jooyoung Jeong, Yijie Lu, Mitchell A. Winnik, Jean-Philippe Pignol, Raymond M. Reilly*, "Dual-receptor-targeted (DRT) radiation nanomedicine labeled with 177Lu is more potent for killing human breast cancer cells that coexpress HER2 and EGFR than single-receptor-targeted (SRT) radiation nanomedicines", Molecular Pharmaceutics, 2020, 17(4), 1226-1236.

• Asmita Banstola, Tung Thanh Pham, Jee-Heon Jeong, Simmyung Yook*, "Polydopamine-tailored paclitaxel-loaded polymeric microspheres with adhered NIR-controllable gold nanoparticles for chemo-phototherapy of pancreatic cancer", Drug delivery, 2019, 26(1), 629-640.

• Shobha Regmi, Shiva Pathak, Tung Pham Thanh, Tiep Tien Nguyen, Jong-Hyuk Sung, Simmyung Yook,  Jong Oh Kim, Chul Soon Yong, Inho Choi, Kyoung-Oh Doh, Pil-Hoon Park, Jun-Beom Park, Yoojin Seo, Bieong-Kil Kim, Dong-Mok Lee, Ik-Jae Moon, Hyung-Sik Kim*, Jee-Heon Jeong*, "Intraportally delivered stem cell spheroids localize in the liver and protect hepatocytes against GalN/LPS-induced fulminant hepatic toxicity", Stem cell research & therapy, 2019, 10, 1-14.

• Shobha Regmi†, Shiva Pathak†, Mahesh Raj Nepal, Prakash Shrestha, Junhyeung Park, Jong Oh Kim, Chul Soon Yong, Dong-Yong Choi, Jae-Hoon Chang, Tae Cheon Jeong, Gorka Orive, Simmyung Yook*, Jee-Heon Jeong*, "Inflammation-triggered local drug release ameliorates colitis by inhibiting dendritic cell migration and Th1/Th17 differentiation". Journal of Controlled Release, 2019, 316, 138-149.

• Tiep Tien Nguyen†, Tung Thanh Pham†, Hanh Thuy Nguyen, Mahesh Raj Nepal, Cao Dai Phung, Zhiwei You, Nikita Katila, Nirmala Tillija Pun, Tae Cheon Jeong, Dong-Young Choi, Pil-Hoon Park, Chul Soon Yong, Jong Oh Kim, Simmyung Yook*, Jee-Heon Jeong*, "Engineering “cell-particle hybrids” of pancreatic islets and bioadhesive FK506-loaded polymeric microspheres for local immunomodulation in xenogeneic islet transplantation". Biomaterials, 2019, 221, 119415.

• Ramesh Duwa, Fakhrossadat Emami, Sooyeun Lee, Jee-Heon Jeong*, Simmyung Yook*, "Polymeric and lipid-based drug delivery systems for treatment of glioblastoma multiforme", Journal of Industrial and Engineering Chemistry, 2019, 79, 261-273.

• Tung Thanh Pham, Hanh Thuy Nguyen, Cao Dai Phung, Shiva Pathak, Shobha Regmi, Dong-Ho Ha, Jong Oh Kim, Chul Soon Yong, Sang Kyoon Kim, Ji-Eun Choi, Simmyung Yook*, Jun-Beom Park*, Jee-Heon Jeong*, "Targeted delivery of doxorubicin for the treatment of bone metastasis from breast cancer using alendronate-functionalized graphene oxide nanosheets",  Journal of Industrial and Engineering Chemistry, 2019, 76, 310-317.

• Fakhrossadat Emami, Asmita Banstola, Alireza Vatanara, Sooyeon Lee, Jong Oh Kim,Jee-Heon Jeong*, Simmyung Yook*, "Doxorubicin and anti-PD-L1 antibody conjugated gold nanoparticles for colorectal cancer photochemotherapy",  Molecular pharmaceutics, 2019, 16(3), 1184-1199.

2015 ~ 2018

• Tung Thanh Pham, Tiep Tien Nguyen, Shiva Pathak, Shobha Regmi, Hanh Thuy Nguyen, Tuan Hiep Tran, Chul Soon Yong, Jong Oh Kim, Pil-Hoon Park, Min Hui Park, Young Kyung Bae, Jeong Uk Choi, Youngro Byun, Cheol-Hee Ahn, Simmyung Yook*, Jee-Heon Jeong*, "Tissue adhesive FK506–loaded polymeric nanoparticles for multi–layered nano–shielding of pancreatic islets to enhance xenograft survival in a diabetic mouse model", Biomaterials, 154, 182-196.

• Asmita Banstola, Fakhrossadat Emami, Jee-Heon Jeong*, Simmyung Yook* "Current applications of gold nanoparticles for medical imaging and as treatment agents for managing pancreatic cancer", Macromolecular Research, 2018, 26, 955-964.

• Shiva Pathak, Shobha Regmi, Tiep Tien Nguyen, Biki Gupta, Milan Gautam, Chul Soon Yong, Jong Oh Kim, Youlim Son, Jae-Ryong Kim, Min Hui Park, Young Kyung Bae, So Young Park, Daewon Jeong, Simmyung Yook*, Jee-Heon Jeong*, "Polymeric microsphere-facilitated site-specific delivery of quercetin prevents senescence of pancreatic islets in vivo and improves transplantation outcomes in mouse model of diabetes", Acta Biomaterialia, 2018, 75, 287-299.

• Pham Tung, Nguyen Tiep, Pathak Shiva, Regmi Shobha, Yong Chul Soon, Kim Jong Oh, Yook Simmyung, Jeong Jee-Heon, "Local Attenuation of Immunoreaction in Xenogeneic Islet Transplantation by Controlled Release of a Low-Dose FK506 using Polydopamine-coated Polymeric Microspheres Immobilized on Pancreatic Islet Surface". Transplantation, 2018, 102, S370-S371.

• Pathak, Shiva, Regmi, Shobha, Pham Tung Thanh, Yong Chul Soon,Kim Jong Oh, Yook Simmyung, Park Min-Hui, Bae Yong Kyung, Jeong Jee-Heon, "Delivery of Pancreatic Islets and Single Dose Local Immune Suppression Into Subcutaneous Space Using Injectable Hydrogel Provides Indefinite Survival of the Graft in Mouse Model of Diabetes", Transplantation, 2018, 102, S76.

• Zhongli Cai, Simmyung Yook, Yijie Lu, Dane Bergstrom, Mitchell A. Winnik, Jean-Philippe Pignol, Raymond M. Reilly*, "Local radiation treatment of HER2-positive breast cancer using trastuzumab-modified gold nanoparticles labeled with 177 Lu", Pharmaceutical research, 2017. 34, 579-590.

• Shiva Pathak, Shobha Regmi, Biki Gupta, Bijay K Poudel, Tung Thanh Pham, Chul Soon Yong, Jong Oh Kim, Jae-Ryong Kim, Min Hui Park, Young Kyung Bae, Simmyung Yook, Cheol-Hee Ahn, Jee-Heon Jeong*, "Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice". Drug Delivery, 2017, 24(1), 1350-1359.

• Zhongli Cai, Simmyung Yook, Yijie Lu, Dane Bergstrom, Mitchell A. Winnik, Jean-Philippe Pignol, Raymond M. Reilly*, "Local radiation treatment of HER2-positive breast cancer using trastuzumab-modified gold nanoparticles labeled with 177 Lu", Pharmaceutical research, 2017. 34, 579-590.

• Shiva Pathak, Shobha Regmi, Biki Gupta, Bijay K Poudel, Tung Thanh Pham, Chul Soon Yong, Jong Oh Kim, Jae-Ryong Kim, Min Hui Park, Young Kyung Bae, Simmyung Yook, Cheol-Hee Ahn, Jee-Heon Jeong*, "Single synchronous delivery of FK506-loaded polymeric microspheres with pancreatic islets for the successful treatment of streptozocin-induced diabetes in mice". Drug Delivery, 2017, 24(1), 1350-1359.

• Shiva Pathak, Shobha Regmi, Biki Gupta, Tung Thanh Pham, Chul Soon Yong, Jong Oh Kim, Simmyung Yook, Jae-Ryong Kim, Min Hui Park, Young Kyung Bae, Jee-Heon Jeong*, "Engineered islet cell clusters transplanted into subcutaneous space are superior to pancreatic islets in diabetes", The FASEB Journal, 2017, 31(11), 5111-5121.

• Shobha Regmi, Jiafu Cao, Shiva Pathak, Biki Gupta, Bijay Kumar Poudel, Pham Thanh Tung, Simmyung Yook, Jun-Beom Park, Chul Soon Yong, Jong Oh Kim, Jin-Wook Yoo*, Jee-Heon Jeong*, "A three-dimensional assemblage of gingiva-derived mesenchymal stem cells and NO-releasing microspheres for improved differentiation", International journal of pharmaceutics, 2017, 520(1-2), 163-172.

• Zhongli Cai, Priscilla Lai, Simmyung Yook, Yijie Lu, Deborah Scollard, Mitchell Winnik, Jean-Philippe Pignol, Raymond Reilly "Auger-gold-A novel radiation nanomedicine for treatment of small metastases from triple-negative breast cancer", The Journal of Nuclear Medicine, 2017, 58, 677.

• Simmyung Yook, Zhongli Cai, Yijie Lu, Mitchell A. Winnik, Jean-Philippe Pignol, Raymond M. Reilly, "Intratumorally injected Lu-labeled gold nanoparticles: gold nanoseed brachytherapy with application for neoadjuvant treatment of locally advanced breast cancer". Journal of Nuclear Medicine, 2016, 57(6), 936-942.

• Simmyung Yook†, Yijie Lu†, Jenny Jooyoung Jeong, Zhongli Cai, Lemuel Tong, Ramina Alwarda, Jean-Philippe Pignol, Mitchell A Winnik*, Raymond M Reilly*, "Stability and biodistribution of thiol-functionalized and (177)Lu-labeled metal chelating polymers bound to gold nanoparticles". Biomacromolecules, 2016, 17(4), 1292-1302.

• Jee-Heon Jeong†, Simmyung Yook†, Youngro Byun*, "Dose optimization of tacrolimus for improving survival time of PEGylated islets in a rat-to-mouse xenograft model", Macromolecular Research, 2016, 24, 1047-1054.

• Simmyung Yook, Zhongli Cai, Yijie Lu, Mitchell A. Winnik, Jean-Philippe Pignol, Raymond M. Reilly*, "Radiation nanomedicine for EGFR-positive breast cancer: panitumumab-modified gold nanoparticles complexed to the β-particle-emitter, 177Lu", Molecular pharmaceutics, 2015, 12(11), 3963-3972.

• So Jin Lee†, Simmyung Yook†, Ji Young Yhee, Hong Yeol Yoon, Myung-Goo Kim, Sook Hee Ku, Sun Hwa Kim, Jae Hyung Park, Ji Hoon Jeong, Ick Chan Kwon, Seulki Lee, Hyukjin Lee, Kwangmeyung Kim, "Co-delivery of VEGF and Bcl-2 dual-targeted siRNA polymer using a single nanoparticle for synergistic anti-cancer effects in vivo", Journal of Controlled Release, 2015 220, 631-641.

† These authors equally contributed as first authors  

* These authors equally contributed as corresponding authors