Mosquitoes
About the Research
We are currently studying the identity and function of seminal fluid proteins of Aedes mosquitoes. Seminal fluid proteins are produced by males and transferred to females during mating. In some Aedes species, these proteins can influence female reproductive and feeding behavior and physiology.
(Image Credit: Vectorbase.org)
News Coverage:
Related Publications:
Sirot, L.K. 2019. Modulation of seminal fluid molecules by males and females. Curr Opin Insect Sci35: 109-116. [Link]
Sirot, L.K. 2019. On the evolutionary origins of insect seminal fluid proteins. Gen Comp Endocrinol278: 104-111. [Link]
Gilkey P.L., D.T. Bolshakov, J.G. Kowala, L.A. Taylor, S. O’Donnell, D.R. Marenda, & L.K. Sirot.2018. Lethal effects of erythritol on the mosquito Aedes aegypti Linnaeus (Diptera: Culicidae). J Applied Entomol 142:873–881. [Link]
Boes K.E., Ribeiro J.M.C., Wong A., Harrington L.C., Wolfner M.F., and Sirot, L.K. (2014) Identification and characterization of seminal fluid proteins in the Asian tiger mosquito, Aedes albopictus. PLoS Negl Trop Dis 8(6): e2946. [Full text]
Alfonso-Parra, C., F.W. Avila, P. Deewatthanawong, L.K. Sirot, M.F. Wolfner, & L.C. Harrington. 2014. Synthesis, depletion and cell-type expression of a protein from the male accessory glands of the dengue vector mosquito Aedes aegypti. Journal of Insect Physiology, 70:117-124.
Helinski, M.E., Deewatthanawong, P., Sirot, L.K., Wolfner, M.F., and Harrington, L.C. (2012). Duration and dose-dependency of female sexual receptivity responses to seminal fluid proteins inAedes albopictus and Ae. aegypti mosquitoes. J. Insect Physiol. 58(10), 1307-1313. [Full text]
Sirot, L.K., Hardstone, M.C., Helinski, M.E.H., Ribeiro, J.M.C., Kimura, M., Deewatthanawong, P., Wolfner, M.F., and Harrington, L.C. (2011). Towards a semen proteome of the dengue vector mosquito: Protein identification and potential functions. Plos Neglect. Trop. Dis. 5. [Full text]
Avila, F.W., Sirot, L.K., LaFlamme, B.A., Rubinstein, C.D., and Wolfner, M.F. (2011). Insect seminal fluid proteins: identification and function. Annual Review of Entomology, 56, 21–40.
Sirot, L.K., Poulson, R.L., McKenna, M.C., Girnary, H., Wolfner, M.F., and Harrington, L.C. (2008). Identity and transfer of male reproductive gland proteins of the dengue vector mosquito, Aedes aegypti: Potential tools for control of female feeding and reproduction. Insect Biochem. Mol. Biol.38, 176–189. [Full text]
