Instruments

We have our own 'home-build' Single Molecule Forster Resonance Energy Transfer (smFRET) setup with Prism-type Total Internal Reflection (TIRF) Microscopy, familiar amongst us as Green Lantern. Currently we can perform 2 colour FRET but we also plan to develop a 3 colour FRET setup in future.

We have Fluorescence Correlation Spectroscopy (FCS) setup in our lab which we use to determine the diffusion coefficients and hydrodynamic radius of various bio-molecules.

We are interested in building the setup of Optical Tweezer combined with smFRET using a IR laser to trap and 532nm laser for the smFRET very soon.