Field Notes

Opinion & Perspective

Designing an Always‑On Biosensing Steering WheelA practical blueprint for smart wheels that quietly monitor heart, stress and alcohol' meeting safety mandates while protecting privacy

Unanswered Questions in Human Evolution Through the Lens of Host-Microbe Co-evolutionThe human holobiont, evolved as an integrated unit, so many mysteries of our evolution may involve microbial partners. Here we revisit key puzzles in hominin evolution.

preLights

Environmental and Maternal Imprints on Infant Gut Metabolic Programming - preLightsLongitudinal multi-omics of 55 Bangladeshi mother-infant dyads shows that delivery mode, water treatment and milk composition shape early gut bile-acid and N-acyl lipid signals, pointing to modifiable levers in infant metabolic programming

Protocol

Analysis of Couples’ Microbiomes and Health OutcomesBackground: Cohabiting partners share more similar microbiomes across gut, oral, skin, and genital sites than unrelated individuals, with metagenomic studies demonstrating measu...

Investigating HARs in Neurodevelopment via Host–Microbe–Metabolite Interactions: A Computational ProtocolHuman Accelerated Regions (HARs) are rapidly evolved genomic loci thought to contribute to human-specific traits, including brain development. Recent studies suggest that some H...

Quantifying Cellular LipidsThis protocol provides a fast, plate-based workflow to quantify cellular lipids using polarity-resolved Nile Red fluorescence coupled with crystal-violet (CV) biomass normalizat...

Biophysicon (blog)

Fractals from Buckling CellsFractals from Buckling Cells Inside a circular colony, uniaxial growth and crowding trigger buckling of cell files; recursive folding yields self-similar, asymmetric branches, emergent geometry fro…

The Wood-Wide Web in Living LightThe Wood-Wide Web in Living Light An underground mycelial internet links neighboring trees, trading photosynthate sugars for nitrogen and phosphorus, shuttling water, and relaying drought/disease w…

Local Activation, Global Design: A Turing Pattern PortraitLocal Activation, Global Design: A Turing Pattern Portrait A false-color study of reaction–diffusion morphogenesis, where a slow-diffusing activator and a faster inhibitor self-organize into spots,…

The 137.5° BlueprintThe 137.5° Blueprint Across sunflower heads, pine cones, and rosettes, successive organs placed ~137.5° apart self-organize into counter-rotating Fibonacci spirals, encoding an efficient meristem-d…

Cold Light, Living NightCold Light, Living Night On a moonless shore, plankton, jellies, lanternfish, fungi, and fireflies script blue-green messages, the shared luciferin–luciferase language stitched across water, roots,…

Architects of LightArchitects of Light Three structural routes to color in one frame, ridge-lamella interferometers on Morpho scales, 2D melanin-keratin photonic crystals in peacock barbules, and quasi-ordered “photo…

Skin That Thinks in 3DSkin That Thinks in 3D An octopus drives millisecond chromatophore pixels, tunable reflectin-based iridophores, broadband leucophores, and neurally actuated papillae to match sand and rock, while a…

The Icosahedral BlueprintSymmetry in Defense: The Icosahedral Blueprint Twenty equilateral faces and twelve pentamer anchors, arranged by quasi-equivalence, form a near-perfect sphere. An efficient, minimal-parts capsid th…

Radial Ribs of a DiatomGlass from a Seed: Radial Ribs of a Diatom From a single central seed, Thalassiosira pseudonana drives a self-replicating reaction–diffusion wave that lays branching silica ribs radially inside a s…

Living RailsLiving Rails: How a Brainless Cell Draws the Smartest Lines Physarum polycephalum grows a broad mesh, then strengthens high-flux tubes and retracts low-use links, converging on efficient, fault-tol…

Deception by DesignDeception by Design: Batesian, Müllerian, and the Predator’s Masquerade A three-panel portrait of mimicry: harmless impostors borrowing aposematic costumes (Batesian), defended species co-branding …

The Gecko’s Dry, Directional AdhesiveHierarchy of Hold: The Gecko’s Dry, Directional Adhesive Lamellae packed with millions of setae that split into ~200-nm spatulae, topped by ordered, nanometer-thin lipids, create dry van der Waals …

Hexagon LogicHexagon Logic: Nature’s Proof-Backed Lattice Bees tile wax into regular hexagons, the equal-area tiling with the least perimeter, packing maximum honey with minimal material while forming a lightwe…

PREreview

PREreview of "Short-term microbial community responses to an intense simulated precipitation pulse in the hyperarid Atacama Desert soil"

PREreview of "Data-Centric AI for EEG-Based Emotion Recognition: Noise Filtering and Augmentation Strategies"

PREreview of "The Influence of Hatching on Blastocyst Metabolomic Analysis: Mass Spectral Analysis of Spent Blastocyst Media in Ai/ML Prediction of IVF Embryo Implantation Potential– To Hatch or Not to Hatch?"

PREreview of "Intrinsic Resistance of the Hippocampal CA2 Subfield to Neuroinflammation After Status Epilepticus"

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