Publications since Joining CNU:
J Iqbal*, SH Kim*, and P Shrestha. The dynamics of protein synthesis regulation in memory systems. Trans. Psychiat., Manuscript in preparation (* equal contribution)
Selected Publications:
A Accogli*, SJ Lin*, M Severino*, SH Kim*, K Huang, C Rocca, M Landsverk, M Zaki, A Al-Maawali, VM Srinivasan, K Al-Thihli, B Schaefer, M Davis, D Tonduti, C Doneda, LM Marten, C Mühlhausen, M Gomez, E Lamantea, R Mena, M Nizon, V Procaccio, A Begtrup, A Telegrafi, H Cu, HL Schulz, J Mohr, S Biskup, MA Loos, HV Aráoz, V Salpietro, LD Keppen, M Chitre, C Petree, L Raymond, J Vogt, LB Swayer, AA Basinger, SV Pederson, TS Pearson, DK Grange, L Lingapp, P McDunnah, R Horvath, B Cognè, B Isidor, A Hahn, K Gripp, SM Jafarnejad, E Østergaard, CE Prada, D Ghezzi, VK Gowda, RW Taylor, N Sonenberg, H Houlden, M Sissler, GK Varshney, and R Maroofian. Clinical, neuroradiological, and molecular characterization of mitochondrial threonyl-tRNA synthetase (TARS2)-related disorder. Genet. Med., 25(11):100938, 2023 (* equal contribution) [JIF2023 90.8% in Genetics & Heredity] [Pubmed]
SH Kim, JH Choi, L Marsal-García, M Amiri, A Yanagiya, and N Sonenberg. The mRNA translation initiation factor eIF4G1 controls mitochondrial oxidative phosphorylation, axonal morphogenesis, and memory. Proc. Natl. Acad. Sci. U. S. A., 120(25):e2300008120, 2023 [JIF2023 90.7% in Multidisciplinary Sciences] [Pubmed] [한빛사]
SH Kim, JH Choi, P Wang, CD Go, GG Hesketh, AC Gingras, SM Jafarnejad, and N Sonenberg. Mitochondrial threonyl-tRNA synthetase TARS2 is required for threonine-sensitive mTORC1 activation. Mol. Cell, 81(2):398-407.e4, 2021 [JIF2021 97.9% in Biochemistry & Molecular Biology] [Pubmed] [한빛사]
SM Jafarnejad*, SH Kim*, and N Sonenberg. Aminoacylation of proteins: new targets for the old ARSenal. Cell Metab., 27(1):1-3, 2018 (* equal contribution) [JIF2018 98.3% in Endocrinology & Metabolism] [Pubmed] [한빛사]
SH Kim, KH Lee, DY Kim, E Kwak, S Kim, and KT Kim. Rhythmic control of mRNA stability modulates circadian amplitude of mouse Period3 mRNA. J. Neurochem., 132(6):642-656, 2015 [Pubmed]
Co-authored Publications:
P Wang, Z Li, SH Kim, H Xu, H Huang, C Yang, A Snape, JH Choi, S Bermudez, MN Boivin, N Ferry, J Karamchandani, B Nagar, and N Sonenberg. PPM1G dephosphorylates eIF4E in control of mRNA translation and cell proliferation. Life Sci. Alliance, 7(10):e202402755, 2024 [Pubmed]
E Krochmalnek*, A Accogli*, J St-Onge, N Addour-Boudrahem, G Prakash, SH Kim, T Brunette-Clément, G Alhajaj, L Mougharbel, E Bruneau, K Myers, F Dubeau, J Karamchandani, JP Farmer, J Atkinson, J Hall, C Poulin, B Rosenblatt, JL Lapalme, A Weil, C Fallet-Bianco, S Albrecht, N Sonenberg, JB Rivière, R Dudley, and M Srour. mTOR pathway somatic mutations in focal malformations of cortical development: novel variants, topographic mapping, and clinical outcomes. Neurology: Genetics (* equal contribution), 9(6):e200103, 2023 [Pubmed]
K Chalkiadaki, M Hooshmandi, G Lach, E Statoulla, K Simbriger, IS Amorim, S Kouloulia, M Zefeiri, P Pothos, É Bonneil, I Gantois, J Popic, SH Kim, C Wong, R Cao, NH Komiyama, Y Atlasi, SM Jafarnejad, A Khoutorsky, and CG Gkogkas. Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1. Brain, 146(5):2175-2190, 2023 [Pubmed]
X Zhang, C Chapat, P Wang, JH Choi, Q Li, J Luo, S Wiebe, SH Kim, N Robichaud, IF Karam, D Dai, AP Hackett, R Lin, T Alain, L Yang, SM Jafarnejad, and N Sonenberg. microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP. Mol. Cell, 81(6):1187-1199.e5, 2021 [Pubmed]
S Wiebe, XQ Meng, SH Kim, X Zhang, JC Lacaille, A Aguilar-Valles, and N Sonenberg. The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and is necessary for social behavior. Mol. Autism, 11(1):92, 2020 [Pubmed]
AM Mohammad, SH Kim, N Bertos, W El-Assaad, I Nandi, H Smith, J Yang, O Chen, I Gamache, T Rao, B Gagnon, T Gruosso, ML Tremblay, N Sonenberg, MC Guiot, W Muller, M Park, and JG Teodoro. Elevated V-ATPase activity following PTEN loss is required for enhanced oncogenic signaling in breast cancer. Mol. Cancer Res., 18(10):1477-1490, 2020 [Pubmed]
D Pearl, S Katsumura, M Amiri, N Tabatabaei, X Zhang, V Vinette, X Pang, ST Beug, SH Kim, LM Jones, N Robichaud, SG Ong, JJ Ja, H Ali, ML Tremblay, M Jaramillo, T Alain, M Morita, N Sonenberg, and S Tahmasebi. 4E-BP-dependent translational control of Irf8 mediates adipose tissue macrophage inflammatory response. J. Immunol., 204(9):2392-2400, 2020 [Pubmed]
JH Choi, SH Kim, YH Jeong, SW Kim, KT Min, and KT Kim. hnRNP Q regulates internal ribosome entry site-mediated fmr1 translation in neurons. Mol. Cell. Biol., 39(4):e00371-18, 2019 [Pubmed]
JH Choi, W Wang, D Park, SH Kim, KT Kim, and KT Min. IRES-mediated translation of cofilin regulates axonal growth cone extension and turning. EMBO J., 37(5):e95266, 2018 [Pubmed]
SM Jafarnejad, C Chapat, E Matta-Camacho, IA Gelbert, GG Hesketh, M Arguello, A Garzia, SH Kim, J Attig, M Shapiro, M Morita, A Khoutorsky, T Alain, CG Gkogkas, N Stern-Ginossar, AC Gingras, T Duchaine, and N Sonenberg. Translational control of ERK signaling through miRNA/4EHP directed silencing. eLife, 7:e35034, 2018 [Pubmed]
H Song, W Kim, SH Kim, and KT Kim. VRK3-mediated nuclear localization of HSP70 prevents glutamate excitotoxicity-induced apoptosis and Aβ accumulation via enhancement of ERK phosphatase VHR activity. Sci. Rep., 6:38452, 2016 [Pubmed]
H Song, W Kim, JH Choi, SH Kim, D Lee, CH Park, S Kim, DY Kim, and KT Kim. Stress-induced nuclear translocation of CDK5 suppresses neuronal death by downregulating ERK activation via VRK3 phosphorylation. Sci. Rep., 6:28634, 2016 [Pubmed]
KH Lee, SH Kim, HJ Kim, W Kim, HR Lee, Y Jung, JH Choi, KY Hong, SK Jang, and KT Kim. AUF1 contributes to Cryotpchrome1 mRNA degradation and rhythmic translation. Nucleic Acids Res., 42(6):3590-3606, 2014 [Pubmed]
KH Lee, SH Kim, HR Lee, W Kim, DY Kim, JC Shin, SH Yoo, and KT Kim. MicroRNA-185 oscillation controls circadian amplitude of mouse CRYPTOCHROME1 via translation regulation. Mol. Biol. Cell, 24(14):2248-2255, 2013 [Pubmed]
DY Kim, W Kim, KH Lee, SH Kim, HR Lee, HJ Kim, Y Jung, JH Choi, and KT Kim. hnRNP Q regulates translation of p53 in normal and stress condition. Cell Death Differ., 20(2):226-234, 2013 [Pubmed]
KH Lee, SH Kim, DY Kim, S Kim, and KT Kim. Internal ribosomal entry site-mediated translation is important for rhythmic PERIOD1 expression. PLoS ONE, 7(5):e37936, 2012 [Pubmed]
DY Kim, E Kwak, SH Kim, KH Lee, KC Woo, and KT Kim. hnRNP Q mediates a phase-dependent translation-coupled mRNA decay of mouse Period3. Nucleic Acids Res., 39(20):8901-8914, 2011 [Pubmed]
Preprints:
S Bermudez, JH Choi, JW Vogel, SH Kim, N Mahmood, VY Zhu, D Cozachenco, M Yaqubi, L Zhou, JA Stratton, O Hansson, L Healy, A Aguilar-Valles, and N Sonenberg. Translational control of microglial inflammatory and neurodegenerative responses. bioRxiv, doi:10.1101/2024.04.06.587750, 2024 [bioRxiv]