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Explore a novel spectroscopic photoacoustic (PA) imaging solution to detect neurovascular bundles (NVBs) during robot-assisted pelvic surgical procedures including radical prostatectomies. This research is motivated by the high rate of nerve damage associated post-operative complications from pelvic surgery and the need for a reliable guidance system to assist surgeons in detecting and preserving these delicate structures. The project involves the conceptualization and instrumentation of a customized PA laparoscope utilizing diffusing optical fibers, the formulation of algorithms for sPA NVB detection based on spectrum unmixing, the integration of the laparoscope with the da Vinci surgical system, the development of algorithms enabling PA imaging augmentation on the surgeon console, and an ex vivo study to provide a demonstration. (Collaboration with Dr. Loris Fichera, Dr. Gregory S. Fischer, Dr. Benjamin Nephew, Worcester Polytechnic Institute, USA)
Related Publications
Shang Gao, Yang Wang, Xihan Ma, Haoying Zhou, Kehan Yang, Liang Lu, Shiyue Wang, Benjamin C. Nephew, Loris Fichera, Gregory S. Fischer, Haichong K. Zhang, "Intraoperative Laparoscopic Photoacoustic Image Guidance System in the da Vinci Surgical System”, Biomedical Optics Express 14 (9), 4914-4928 (2023) [Link]
Shang Gao, Yiwei Jiang, Mucheng Li, Yang Wang, Yao Shen, Matthew C. Flegal, Benjamin C. Nephew, Gregory S. Fischer, Yuxiang Liu, Loris Fichera, Haichong K. Zhang, “Laparoscopic Photoacoustic Imaging System Based on Side-illumination Diffusing Fibers”, IEEE Transactions on Biomedical Engineering, vol. 70, no. 11, pp. 3187-3196, Nov. 2023 - Featured Article in TBME November Issue, 2023 [Link]
Shang Gao, Yang Wang, Haoying Zhou, Kehan Yang, Yiwei Jiang, Liang Lu, Shiyue Wang, Xihan Ma, Benjamin Nephew, Loris Fichera, Gregory S. Fischer, Haichong K. Zhang, "Laparoscopic Photoacoustic Imaging System Integrated with the da Vinci Surgical System", SPIE Medical Imaging 2023 - (the Robert F. Wagner All-Conference Best Student Paper Award) [Conference Link]
Shang Gao, Matthew C. Flegal, Haichong K. Zhang, "Feasibility of laparoscopic photoacoustic imaging system based on diffusing side-illumination fibers," Proc. SPIE 11960, Photons Plus Ultrasound: Imaging and Sensing 2022, 119601C (3 March 2022) [Link]
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