Sebastian E. Ramos-Onsins
ORCID: 0000-0002-1776-140X
Approches to Understand the Genetic Variability
We aim to understand the evolutionary processes occurring in populations. On one side, we develop statistical methods and perform simulation studies with the goal of improving the detection of specific patterns of variability, using population genomics perspective but also combining phenotype and environmental information. On another side, we analyze empirical genomic data from wild and domesticated populations to detect the effect of positive selection and other evolutionary processes.
Research
We develop statistical methodologies focused in distinguishing the different evolutionary forces, such as detecting the effects on traits affected by positive selection.
To release software for the analysis of variability is of great importance to spread our methodologies and to allow that other researchers perform analysis using our perspective.
In close collaboration with Dr. M. Abdelaziz (University of Granada) we aim to explore the effects of changes in ploidy and mating systems on ecological and genetic mechanisms that in turn mediate the selective patterns (adaptive trajectories) that appear in different environments.
In domestic species, artificial selection is expected acting on traits of human interest. We are interested in the genetic architecture of adaptation by domestication. Simulation studies can help to define the expectations under each hypothesis and to establish the statistical power to distinguish both hypotheses.
Who we are
ORCID: 0000-0002-1776-140X
PhD in Population Genetics at University of Barcelona (UB, Barcelona, Spain)
PostDoc in Human Genetics Center (Houston, Texas)
PostDoc in Max-Planck Institute (Chemical Ecology, Jena, Germany)
Assistant Professor at UB (Barcelona)
Ramon y Cajal Researcher at CRAG
Diego started his thesis with the title “Análisis transcriptómico de la lactación y cartografiado fino de polimorfismos con efectos causales sobre fenotipos lecheros y de viabilidad en la raza Murciano-Granadina”. This thesis is part of a collaboration between three PI from CRAG (Marcel Amills, Alex Clop and Sebastian Ramos-Onsins).
Alumni
Grade and Master Students, PhD students and PostDocs contributed to the lines of the Group. Here they are.
Publications
See the list of publications at PubMed, Google Scholar, biorxiv, and ORCID.
Software and Datasets
Most of developed software can be seen at Github at sramosonsins and in CRAGENOMICA.
See here for more information about other software, datasets and additional documents.
Teaching and Outreach
I impart classes regularly in the following courses:
Master in Bioinformatics at University Autonomous of Barcelona (UAB,Barcelona).
Instituto Agronómico Mediterraneo de Zaragoza (IAMZ) at the faculty of Veterinary (UAB, Bellaterra).
Postgraduate course Filogenias y Genealogias de DNA: Reconstrucción y Aplicaciones (Universitat de Barcelona).
I also collaborate with other Education Centers to spread the importance of Science and Evolution for the Society.