Criteria for Decision-Making Capacity and Neuroscience. February 17, 2017. This is a short talk and panel discussion at the Translating Neuroscience for Law, Clinical Care & Policy conference at the UCSF/Hastings School of Law.
Ethical Issues in Pragmatic RCTs in Learning Health Systems. November 18, 2016. Ethical, Legal, Social Implications of LHS Conference, University of Michigan, Ann Arbor. A relatively brief synopsis of key ethical issues in conducting pragmatic RCTs in 'learning health systems.'
Ethical Issues in Trials within Cohorts. November 7, 2016. This was a keynote at the 2nd international symposium on Trials within Cohorts (TwiCs) in London, UK. Although I touch on 'standard of care' RCTs, this is primarily an ethical analysis of a novel pragmatic design called 'Trials within Cohorts' which combines a cohort design with post-randomization consent for trials within those cohorts.
Ethics of Pragmatic Randomized Clinical Trials. November 16, 2016. This is a lecture I give annually during the NIH Clinical Center's course on research ethics, "Ethical and Regulatory Aspects of Clinical Research."
Research Involving Persons with Impaired Decision-Making Capacity. October 2016. This is a lecture I give annually during the NIH Clinical Center's course on research ethics, "Ethical and Regulatory Aspects of Clinical Research." The talk starts at about 57:00.
Physician Assisted Death of Non-Terminally Ill Psychiatric Patients. September 12, 2016. A talk given as part of the Johns Hopkins Berman Institute Seminar Series. A data-based overview of the practice of euthanasia of the mentally ill in the Netherlands and Belgium.
Testimony, Canadian Senate Committee on Legal and Constitutional Affairs. May 11, 2016. The session in which I participated begins around 16:30. I was one of three witnesses. My testimony begins at approximately 16:38 with a personal statement. Most of the hour is taken up by a Dr. Derryk Smith, a psychiatrist from Dignity in Dying Canada. I do provide a closing set of comments at 17:26, as a counterbalance to some of the assertions made by Smith during the hour.
Therapeutic Misconception and ALS. March 3, 2016. Harvard Center for Bioethics, Neuroethics Seminar (begins at 21:30)
Consent to Research When Participants Have Diminished or Fluctuating Decisional Capacity. December, 15, 2015. University of Minnesota's Consortium on Law and Values in Health, Environment & the Life Sciences
Risk-Benefit Analysis in Clinical Research: What is the Role of Equipoise? August 26, 2015. NIH Clinical Center Grand Rounds.