Publications

For a complete list, see Google scholar.

Selected publications

K. Kocher*, C. Moosmann*, F. Drost, C. Schülein, P. Irrgang, P. Steininger, J. Zhong, J. Träger, B. Spriewald, C. Bock, D. H. Busch, C. Bogdan, B. Schubert, T. H. Winkler, M. Tenbusch, E. M. Schuster*, K. Schober*, Adaptive immune responses are larger and functionally preserved in a hypervaccinated individual. The Lancet Infectious Diseases (2024), doi:10.1016/S1473-3099(24)00134-8

F. Drost, E. Dorigatti, A. Straub, P. Hilgendorf, K. I. Wagner, K. Heyer, M. López Montes, B. Bischl, D. H. Busch*, K. Schober*, B. Schubert*, Predicting T cell receptor functionality against mutant epitopes. Cell Genomics, (2024), doi: 10.1016/j.xgen.2024.100634

A. Straub, S. Grassmann, S. Jarosch, L. Richter, P. Hilgendorf, M. Hammel, K. I. Wagner, V. R. Buchholz, K. Schober*, D. H. Busch*, Recruitment of epitope-specific T cell clones with a low-avidity threshold supports efficacy against mutational escape upon reinfection, Immunity (2023), doi:10.1016/j.immuni.2023.04.010.

P. Irrgang*, J. Gerling*, K. Kocher*, D. Lapuente, P. Steininger, K. Habenicht, M. Wytopil, S. Beileke, S. Schäfer, J. Zhong, G. Ssebyatika, T. Krey, V. Falcone, C. Schülein, A. S. Peter, K. Nganou-Makamdop, H. Hengel, J. Held, C. Bogdan, K. Überla, K. Schober*, T. H. Winkler*, M. Tenbusch*, Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination, Sci. Immunol. (2023), doi:10.1126/sciimmunol.ade2798.

E. Vogel*, K. Kocher*, A. Priller*, C.-C. Cheng*, P. Steininger, B.-H. Liao, N. Körber, A. Willmann, P. Irrgang, J. Held, C. Moosmann, V. Schmidt, S. Beileke, M. Wytopil, S. Heringer, T. Bauer, R. Brockhoff, S. Jeske, H. Mijocevic, C. Christa, J. Salmanton-García, K. Tinnefeld, C. Bogdan, S. Yazici, P. Knolle, O. A. Cornely, K. Überla, U. Protzer*, K. Schober*, M. Tenbusch*, Dynamics of humoral and cellular immune responses after homologous and heterologous SARS-CoV-2 vaccination with ChAdOx1 nCoV-19 and BNT162b2. eBioMedicine. (2022), doi: 10.1016/j.ebiom.2022.104294

A. Purcarea*, S. Jarosch*, J. Barton, S. Grassmann, L. Pachmayr, E. D'Ippolito, M. Hammel, A. Hochholzer, K. I. Wagner, J. H. van den Berg, V. R. Buchholz, J. B. A. G. Haanen, D. H. Busch*, K. Schober*, Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity. Science Immunology (2022), doi:10.1126/sciimmunol.abm2077  (free access link)

D. S. Fischer*, M. Ansari*, K. I. Wagner*, S. Jarosch, Y. Huang, C. H. Mayr, M. Strunz, N. J. Lang, E. D. Ippolito, M. Hammel, L. Mateyka, S. Weber, L. S. Wolff, K. Witter, I. E. Fernandez, K. Milger, M. Frankenberger, L. Nowak, K. Heinig-Menhard, I. Koch, M. G. Stoleriu, A. Hilgendorff, J. Behr, A. Pichlmair, B. Schubert*, F. J. Theis*, D. H. Busch*, H. B. Schiller*, K. Schober*, Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through “reverse phenotyping.” Nature Communications (2021), doi:10.1038/s41467-021-24730-4

K. Schober*, F. Voit*, S. Grassmann, T. R. Müller, J. Eggert, S. Jarosch, B. Weißbrich, P. Hoffmann, L. Borkner, E. Nio, L. Fanchi, C. R. Clouser, A. Radhakrishnan, L. Mihatsch, P. Lückemeier, J. Leube, G. Dössinger, L. Klein, M. Neuenhahn, J. D. Oduro, L. Cicin-Sain, V. R. Buchholz, D. H. Busch, Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection. Nature Immunology 21, 434–441 (2020), doi:10.1038/s41590-020-0628-2

K. Schober*, T. R. Müller*, F. Gökmen, S. Grassmann, M. Effenberger, M. Poltorak, C. Stemberger, K. Schumann, T. L. Roth, A. Marson, D. H. Busch, Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function. Nature Biomedical Engineering 3, 974–984 (2019), doi:10.1038/s41551-019-0409-0.

C. Schuster, K. D. Gerold, K. Schober, L. Probst, K. Boerner, M.-J. Kim, A. Ruckdeschel, T. Serwold, S. Kissler, The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection. Immunity 42, 942–952 (2015), doi:10.1016/j.immuni.2015.04.011.