Publications

For a complete list, see Google scholar.

Selected publications

D. S. Fischer*, M. Ansari*, K. I. Wagner*, S. Jarosch, Y. Huang, C. H. Mayr, M. Strunz, N. J. Lang, E. D. Ippolito, M. Hammel, L. Mateyka, S. Weber, L. S. Wolff, K. Witter, I. E. Fernandez, K. Milger, M. Frankenberger, L. Nowak, K. Heinig-Menhard, I. Koch, M. G. Stoleriu, A. Hilgendorff, J. Behr, A. Pichlmair, B. Schubert*, F. J. Theis*, D. H. Busch*, H. B. Schiller*, K. Schober*, Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through “reverse phenotyping.” Nat. Comm. (2021), doi:10.1038/s41467-021-24730-4

M. Hiltensperger, E. Beltrán, R. Kant, S. Tyystjärvi, G. Lepennetier, H. Domínguez Moreno, I. J. Bauer, S. Grassmann, S. Jarosch, K. Schober, V. R. Buchholz, S. Kenet, C. Gasperi, R. Öllinger, R. Rad, A. Muschaweckh, C. Sie, L. Aly, B. Knier, G. Garg, A. M. Afzali, L. A. Gerdes, T. Kümpfel, S. Franzenburg, N. Kawakami, B. Hemmer, D. H. Busch, T. Misgeld, K. Dornmair, T. Korn, Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity. Nat. Immunol. (2021), doi:10.1038/s41590-021-00948-8.

M. Tenbusch*, S. Schumacher*, E. Vogel, A. Priller, J. Held, P. Steininger, S. Beileke, P. Irrgang, R. Brockhoff, J. Salmanton-García, K. Tinnefeld, H. Mijocevic, K. Schober, C. Bogdan, S. Yazici, P. Knolle, O. A Cornely*, Klaus Überla*, Ulrike Protzer* for the DZIF- VACCELERATE-CoVaKo study team. Heterologous prime–boost vaccination with ChAdOx1 nCoV-19 and BNT162b2. Lancet ID. (2021), doi: 10.1016/ S1473-3099(21)00420-5

T. R. Müller, S. Jarosch, M. Hammel, J. Leube, S. Grassmann, B. Bernard, M. Effenberger, I. Andrae, M. Z. Chaudhry, T. Käuferle, A. Malo, L. Cicin-Sain, P. Steinberger, T. Feuchtinger, U. Protzer, K. Schumann, M. Neuenhahn, K. Schober*, D. H. Busch*, Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy. Cell Rep Med (2021), doi: 10.1016/j.xcrm.2021.100374.

K. Schober*, F. Voit*, S. Grassmann, T. R. Müller, J. Eggert, S. Jarosch, B. Weißbrich, P. Hoffmann, L. Borkner, E. Nio, L. Fanchi, C. R. Clouser, A. Radhakrishnan, L. Mihatsch, P. Lückemeier, J. Leube, G. Dössinger, L. Klein, M. Neuenhahn, J. D. Oduro, L. Cicin-Sain, V. R. Buchholz, D. H. Busch, Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection. Nat. Immunol. 21, 434–441 (2020), doi:10.1038/s41590-020-0628-2

D. Stenger, T. A. Stief, T. Kaeuferle, S. Willier, F. Rataj, K. Schober, B. Vick, R. Lotfi, B. Wagner, T. G. P. Grünewald, S. Kobold, D. H. Busch, I. Jeremias, F. Blaeschke, T. Feuchtinger, Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR. Blood. 136, 1407–1418 (2020), doi:10.1182/blood.2020005185.

T. R. Müller, C. Schuler, M. Hammel, A. Köhler, S. Jutz, J. Leitner, K. Schober*, D. H. Busch*, P. Steinberger*, A T‐cell reporter platform for high‐throughput and reliable investigation of TCR function and biology. Clin. Transl. Immunol. 9, 1–16 (2020), doi:10.1002/cti2.1216.

S. Grassmann*, L. Mihatsch*, J. Mir, A. Kazeroonian, R. Rahimi, S. Flommersfeld, K. Schober, I. Hensel, J. Leube, L. O. Pachmayr, L. Kretschmer, Q. Zhang, A. Jolly, M. Z. Chaudhry, M. Schiemann, L. Cicin-Sain, T. Höfer, D. H. Busch, M. Flossdorf, V. R. Buchholz, Early emergence of T central memory precursors programs clonal dominance during chronic viral infection. Nat. Immunol. 21, 1563–1573 (2020), doi:10.1038/s41590-020-00807-y .

K. Schober*, T. R. Müller*, F. Gökmen, S. Grassmann, M. Effenberger, M. Poltorak, C. Stemberger, K. Schumann, T. L. Roth, A. Marson, D. H. Busch, Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function. Nat. Biomed. Eng. 3, 974–984 (2019), doi:10.1038/s41551-019-0409-0.

T. Hassler, E. Urmann, S. Teschner, C. Federle, T. Dileepan, K. Schober, M. K. Jenkins, D. H. Busch, M. Hinterberger, L. Klein, Inventories of naive and tolerant mouse CD4 T cell repertoires reveal a hierarchy of deleted and diverted T cell receptors. Proc. Natl. Acad. Sci. 116, 18537–18543 (2019), doi:10.1073/pnas.1907615116.

C. Schuster, K. D. Gerold, K. Schober, L. Probst, K. Boerner, M.-J. Kim, A. Ruckdeschel, T. Serwold, S. Kissler, The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection. Immunity. 42, 942–952 (2015), doi:10.1016/j.immuni.2015.04.011.

*equal contribution to first or senior authorship

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