Rahul Singh

PhD Scholar (ICMR-SRF)

Singh is working on biological data within the three-dimensional molecular context, leveraging his knowledge to better understand biological processes, particularly receptor-ligand interactions. Science has always fascinated him and sparked his curiosity to seek solutions from different perspectives. He strives to improve upon his past performance, which keeps him motivated to stay organized and focused on his goals and tasks.

Bhanu Sharma

PhD Scholar (DBT-SRF)

His research focuses on the discovery and evaluation of novel compounds for the treatment of neurological disorders, with a particular emphasis on phosphodiesterase (PDE) inhibitors. Phosphodiesterases, as key regulators of intracellular signaling, have emerged as compelling therapeutic targets for conditions such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Employing a multidisciplinary approach, he utilizes computational drug discovery, high-throughput screening, and in vitro and in vivo zebrafish models to identify and characterize promising PDE inhibitors. His work has led to the identification of several candidate compounds exhibiting high selectivity and potency against specific PDE isoforms implicated in neurodegenerative pathways, offering new hope for advancing treatments in this critical field of medicine.

Pramod Kumar

PhD Scholar (DBT-SRF)

His research focuses on exploring the inclusion complexes of molecules with low solubility with different forms of CDs, to enhance their hydro-solubility. Using a combination of advanced computational and quantum mechanical approaches, he investigates the stability and dynamics of these molecules within the central cavities of CDs. Microsecond-scale molecular dynamics simulations, coupled with Molecular Mechanics Poisson-Boltzmann Surface Area and umbrella sampling techniques.

Dr. Ashish Gupta

PhD (Central University, Himachal Pradesh)

Postdoctoral Fellow (University of Oklahoma)

Previous Position (ICMR-RA) CSIR-IHBT

Current Position (DBT-RA)

Amit Daroch

PhD Scholar (AcSIR)

MSc Bioinformatics (Central University of Himachal Pradesh)

His research focuses on deciphering drug-microRNA relationships using advanced artificial intelligence (AI) and machine learning (ML) approaches. MicroRNAs, as critical regulators of gene expression, play a pivotal role in various diseases, making them valuable targets for therapeutic intervention. By integrating AI/ML techniques with large-scale biological data, his work aims to uncover novel drug-microRNA interactions, predict potential therapeutic targets, and design precision medicines. This innovative approach has enabled the identification of key regulatory pathways and drug candidates, offering transformative insights into personalized medicine and advancing the development of targeted therapies.

Vidhi

PhD Scholar (CSIR-GPAT)

M. Pharma (Shri Guru Ram Rai University)