Thermal Cell Engineering
細胞にお灸を据える
私達は、ミクロな細胞の世界の温度を測ったり、操作したり する技術を開発して、動物・ 植物の垣根を超えた細胞機能の解析・制御に取り組んでいます。従来の遺伝子の切り貼りをせず、化学の力でこれを達成します。ケミカルバイオロジーや生物物理がメイン分野ですが、分野に囚われず、幅広く行ったり来たりしながら、自由な研究を目指すラボです。テーマの持ち込みも歓迎します。
Previous Article (Japanese): Academist Journal
Interview (English): Univ. website
PhD and Master scholarships in NanoLSI
https://gsinfiniti.w3.kanazawa-u.ac.jp/examinee_nano/
学内外の学生さん、学振PDの応募も歓迎です（修士・博士課程＊共に奨学金有）。お気軽にご連絡ください。
Contact Address： satoshi.arai@staff.kanazawa-u.ac.jp
News
2024 May Collaboration paper with Fujiwara-san (Keio univ.) is out！
2024 Mar Arai gave invited talks in 日本薬学会第144年会@横浜 and Leica-luncheon Seminar (第101回日本生理学会大会)@小倉.
2024 Mar Lab members (Takeru, Cong Vu, Loan, Dilini) joined the biophysical society of Japan, Chubu area conference. Congrats on presentation awards, Dr. Cong Vu!
2024 Mar Congrats, Takeru! Completed PhD course!
2024 Jan Arai gave invited talk in 第15回光塾@Tokyo Metropolitan University.hikarijuku.xyz/
2023 Dec Arai gave invited talk in Science Pioneers Consortium2023@Tokyo. 上原記念ホール
2023 Dec Arai joined 第2回動く・流れるソフトマテリアル研究会 ＠Sendai
2023 Dec Our members, Arai (symposium), Loan (poster) and Cong Vu (poster) attended The 46th Annual Meeting of the Molecular Biology Society of Japan@神戸. Thanks you for intensive discussions! (especially, GTP-geek members).
2023 Dec Arai gave invited talk in The 97th Annual Meeting of the Japanese Pharmacological Society@ 神戸
2023 Nov We had lunch party in collaborating with Toda lab! This was awesome family gathering, too. Thank you very much for organizing, Mizuno-kun!
2023 Nov Our members, Arai (symposium), Cong (poster) and Loan (poster), did presentations in The Annual Meeting of the Biophysical Society of Japan. Thank you for coming to sessions! So many guys showed interests in first singleFP based biosensors!
2023 Oct New paper is out! Congrats, Dr. Cong!
"Quantitative Imaging of Genetically Encoded Fluorescence Lifetime Biosensors" in Biosensors
Now, selected as highly accessed paper!
2023 Sep Our members (Arai, Cong, Takeru, Suyan, Loan, Dilini) joined NanoBioCoM2023 in ICISE, Quy Nhon (Vietnam). Dilini got the poster prize!
2023 Aug New paper is posted to bioRxiv! Congrats, Hideki and Cong! This is a first green fluorescence protein based fluorescence lifetime sensor detecting endogenous ATP. www.biorxiv.org/content/10.1101/2023.08.29.555275v1
2023 July New paper is out! Congrats, Takeru! Applicability and Limitations of Fluorescence Intensity-Based Thermometry Using a Palette of Organelle Thermometers
2023 Jun サーキュラーマテリアル コンソーシアム＠湯涌で講演（新井）
2023 May We have a special seminar inviting Dr. Nasu (The univ. of Tokyo, PRESTO researcher). Exciting talk!
2023 May Exciting collaboration with IIT in Italy is done! Farewell party with Alessio.
2023 May Collaboration studies with Ohmiya lab is out in J. Am. Chem. Soc.! nanolsi.kanazawa-u.ac.jp/highlights/26499/
2023 Apr Welcome party was held for Deshan, Shimizu-san, Alessio!
2023 Apr 「温度ストレスによる生体応答ダイナミクス」（NTS出版）の一部、執筆しました。
http://www.nts-book.co.jp/item/detail/summary/bio/20230400_284.html
http://www.nts-book.co.jp/item/detail/summary/bio/20230400_284.html
2023 Apr New members join the lab. Welcome, Shimizu-san and Deshan!
2023 Mar 脳神経医学セミナー＠医学部（金大：河崎先生主催）で講演。
2023 Mar Alessio joined our team as a visiting student from IIT, Italy!
2023 Feb Collaboration paper with Tohoku univ. is out in ACS App. Mater. Nano.
2023 Feb 第一回分子生命反応創発討論会（＠金沢）で開催。
https://sites.google.com/view/mollife/home
2023 Feb Science-omeで喋りました（新井）。
https://www.scienc-ome.com/
2023 Feb 生体分子環境の化学（CSJカレントレビュー）が発刊（１章分担当）。
https://www.kagakudojin.co.jp/book/b615061.html
2022 Dec メカノバイオ討論会2022（Online）。Takeru, Congrats for poster award!
2022 Dec GTP-ハッカソン（GEEK）に参加・講演＠鶴岡。
2022 Nov International Congress on Pure & Applied Chemistry, Kota Kinabaluで招待講演
2022 Oct Congrats, Kawamura-san! JSPS PD fellowship successful!
2022 Sep Monir, Takeru and Cong Vu joined annual meeting of the Biophysical Society of Japan in Hakodate!
Monir was selected to be the speaker in the symposium session. https://www2.aeplan.co.jp/bsj2022/
Monir was selected to be the speaker in the symposium session. https://www2.aeplan.co.jp/bsj2022/
2022 Aug Dilini and Loan joined master course in our lab!
2022 Aug International Chemical Biology & Molecular Imaging Conference 2022 (Online, Pohang in Korea)で講演
2022 Aug Congrats, Takeru and Xiao! New paper, The paper regarding FLIM based organelle thermometers is accepted in Materials Today Bio.
2022 Jun Congrats, Ferdi! Collaboration paper is accepted in Analyst
2022 Jun 村田学術助成 採択。
2022 Jun Kawamura-san joined our team as research staff!
大学のプレスリリース nanolsi.kanazawa-u.ac.jp/achievements/achievements-20342/
2022 Jun タンパク質科学会で招待講演（Arai)
2022 Jun Congrats, Ferdi! New paper, Modulation of Local Cellular Activities using a Photothermal Dye-Based Subcellular-Sized Heat Spot, ACS Nano!
doi.org/10.1021/acsnano.2c00285
doi.org/10.1021/acsnano.2c00285
2021 Dec 新学術領域「分子夾雑化学」関西シンポジウムとPacifihem2021で講演（Arai)。
2021 Dec 新学術領域「分子夾雑化学」関西シンポジウムとPacifihem2021で講演（Arai)。
2021 Dec Farewell for Dr. Satya! Thanks for a ton of efforts to launch new project. And, welcome for Dr. Cong Vu!
2021 Nov ソフトマター工学分科会で講演（Arai)。
http://softmatter-eng.net/
2021 Nov Collaboration paper is out! (with Cheng Pau, and prof. Hashimoto)
http://softmatter-eng.net/
2021 Nov Collaboration paper is out! (with Cheng Pau, and prof. Hashimoto)
2021 Oct メカノバイオ討論会2021を開催します（世話人）。
皆様の参加をお待ちしております。
https://www.biophys.jp/news/lib/newsshow.php/5212
2021 Sep 高分子討論会で招待講演 (Arai)。
皆様の参加をお待ちしております。
https://www.biophys.jp/news/lib/newsshow.php/5212
2021 Sep 高分子討論会で招待講演 (Arai)。
2021 Jun タンパク質科学会の年会で招待講演 (Arai)。
2021 Apr 新学術領域の分子夾雑の生命科学にて成果発表。
2021 Apr 旭硝子財団研究助成金 採択。
2021 Feb JST 創発的研究支援事業 採択。
2020 Nov The article is out in the magazine 「月刊細胞」!
2020 Jun Collaboration with Yoshitaka (Waseda), prof. Fujie (Tokyo Tech.) and prof. Franz (Kanazawa
Univ.) is out!
2020 May Collaboration study with Dr. Sou and prof. Sato in NTU is out!
2020 Feb ERthermAC is commercially available!
ERthermAC, temperature sensor (developed when in prof. Chang lab), is available from Merck!
2019 Dec Collaboration study with Dr. Ken Lee in NTU
Highly cooperative fuorescence switching of self-assembled squaraine dye at tunable threshold temperatures using thermosensitive nanovesicles for optical sensing and imaging, Keitaro Sou, Li Yan Chan, Satoshi Arai, Chi-Lik Ken Lee, Scientific Reports, 9, 17991 (2019).
2019 Nov Collaboration study with Dr. Ken Lee in NTU and prof. Shibata in Waseda univ.
Eurotium Cristatum Fermented Okara as a Potential Food Ingredient to Combat Diabetes, Li Yan Chan, Masaki Takahashi, Pei Jean Lim, Shinya Aoyama, Saneyuki Makino, Ferdinandus Ferdinandus, Shi Ya Clara Ng, Satoshi Arai, Hideaki Fujita, Hong Chang Tan, Shigenobu Shibata, Chi-Lik Ken Lee, Scientific Reports, 9, 17536 (2019).
2019 Oct Collaboration study with prof. Gianni and Attilio in Italy
Multifunctional temozolomide-loaded lipid superparamagnetic nanovectors: Dual targeting and disintegration of glioblastoma spheroids by synergic chemotherapy and hyperthermia treatment, A. Marino, A. Camponovo, A. degl'Innocenti, M. Bartolucci, C. Tapeinos, C. Martinelli, D. de Pasquale, F. Santoro, V. Mollo, S. Arai, M. Suzuki, Y. Harada, A. Petretto, G. Ciofani. Nanoscale, accepted.
2019 Aug Collaboration with A*STAR (Singapore) and POSTEC.
Visualizing Alzheimer’s Disease Mouse Brain with Multispectral Optoacoustic Tomography using a Fluorescent probe, CDnir7, Sung-Jin Park, Chris Jun Hui Ho, Satoshi Arai (co-first), Animesh Samanta, Malini Olivo and Young-Tae Chang, Scientific Reports, 9, 12052 (2019)
2019 July Lab started