We are a pluridisciplinary team of computer scientists, optical engineers, and biologists, fascinated by a simple but incredibly complex question: how do organisms develop from a single cell into a fully functional body with billions of self-organizing cells that form tissues and have different functions? Our bet is that solving this question will require expertise across Computer Science, Microscopy, and Biology. Our goal is to build a Time-Resolved Multi-Dimensional Atlas of Vertebrate Development using Zebrafish as a model organism. To attain this goal, we design and build novel state-of-the-art light-sheet microscopes, as well as conceive of deep-learning based image processing and analysis algorithms.