Peer Reviewed publications:
R Kumar, S Gravett, V Jelic, J Lange, L Oftedal, A Ciullini, M B Bacınoğlu, C M Giulia De Luca, L Hamied, C Birck, F Blanc, P L Hoede, A W Lemstra, M C Gonzalez, D Aarsland, C E Teunissen, Oliver Bousiges, Fabio Moda, J Maple-Grødem, A Abelein, and D Ferreira. Diagnostic Performance of the Alpha-Synuclein Seed Amplification Assay for Dementia with Lewy Bodies: A comparison across four laboratories. Neurology, 2026, 106(4):e214614, Impact factor (IF), 9.00. DOI: 10.1212/WNL.0000000000214614
L Adam, WH Molenkamp, JS Nowak, A Farzadfard, K Gaarthuis, R Kumar, J Nielsen, DE. Otzen, J Johansson and A Abelein. Mechanism-selective inhibition of α-synuclein aggregation by the chaperone-like BRICHOS domain. Journal of Biological Chemistry, 2026,113117, DOI: 10.1016/j.jbc.2026.113117
Z Jin#, WP Olsen#, Cecilia Mörman#, R Kumar#, A Leppert#, LG Nielsen, JY Elosua, A Abelein, M Landreh, S Knight, J Johansson, DE Otzen and G Chen (2025). The protein CagA released by Helicobacter pylori is a potent and broad-spectrum amyloid inhibitor (# Equally contributed author). Science Advances, 11, eads7525, IF- 12.5, DOI: 10.1126/sciadv.ads7525
C Mörman, A Leppert, G Pizzirusso, Z Zheng, X SunKuma, R Kumar, H Biverstål, M Landreh, J Johansson, L Arroyo García, J Luo, G Chen and A Abelein (2025). Chaperone Mediated Regulation of Tau Phase Separation, Fibrillation and Toxicity. Journal of the American Chemical Society,147, 27, 23504–23518, IF- 15.7, DOI: 10.1021/jacs.5c01369
R Kumar, T L Marchand, L Adam, R Bobrovs, G Chen, J Fridmanis, N Kronqvist, H Biverstål, K Jaudzems, J Johansson, G Pintacuda and A Abelein (2024). Identification of aggregation hotspots on Aβ42 fibrils blocked by an anti-amyloid chaperone-like domain. Nature Communication 15, 965, IF- 15.7, https://doi.org/10.1038/s41467- 024-45192-4
L Adam, R Kumar, LE Arroyo-Garcia, WH Molenkamp, JS Nowak, H Klute, A Farzadfard, R Alkenayeh, J Nielsen, H Biverstål, DE Otzen, J Johansson, A Abelein (2024). Specific inhibition of α-synuclein oligomer generation and toxicity by the chaperone domain Bri2 BRICHOS. Protein Science. 33(8):e5091. IF 5.2, DOI: 10.1002/pro.5091.
R Kumar, LEA García, S Manchanda, L Adam, Giusy Pizzirusso, Henrik Biverstål, P Nilsson, Andrè Fisahn, J Johansson and A Abelein (2023). Molecular mechanisms of amyloid-β self-assembly seeded by in vivo derived fibrils and inhibitory effects of the BRICHOS chaperone. ACS Chemical Neuroscience, 14, 8, 1503–1511, IF- 3.9, DOI: 10.1021/acschemneuro.3c00044
C Peña-Bautista, R Kumar, M Baquero, C, Chafer-Pericas, A Abelein, D Ferreira (2023). Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis. Frontier Molecular Bioscience. 10:1193458. IF- 4, DOI: 10.3389/fmolb.2023.1193458
A Abelein, S Ciofi, C Mörman, R Kumar, A Giachetti, M Piccioli, and H Biverstål (2022). Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer’s Disease. Journal of the American Chemical Society Au, 2(11): 2571–2584, IF- 8.7, DOI: 10.1021/jacsau.2c00438
X Zhong, R Kumar, Y Wang, H Biverstål, C I Jegerschöld, P J B Koeck, J Johansson, A Abelein, and G Chen (2022). Amyloid Fibril Formation of Arctic Amyloid-β 1-42 Peptide is Efficiently Inhibited by the BRICHOS Domain. ACS Chemical Biology, 17, 8, 2201–2211. IF- 3.8, DOI: 10.1021/acschembio.2c00344
R Jiang, M Shimozawa, J Mayer, S Tambaro, R Kumar, A Abelein, B Winblad, N Bogdanovic, P Nilsson (2022). Autophagy Impairment in App Knock-in Alzheimer's Model Mice. Frontiers Aging Neuroscience, 14:878303. IF- 4.5, DOI: 10.3389/fnagi.2022.878303
P Kadu, L Gadhe, A Navalkar, K Patel, R Kumar, M Sastry and SK Maji (2022). Charge and hydrophobicity of amyloidogenic protein/peptide templates regulate the growth and morphology of gold nanoparticles. Nanoscale, 14, 15021-15033. IF - 5.1, DOI: 10.1039/d2nr01942f
M Brackhan, G Calza, K Lundgren, P Bascuñana, T Brüning, R Soliymani, R Kumar, A Abelein, M Baumann, M Lalowski, J Pahnke (2022). Isotope-labeled amyloid-β does not transmit to the brain in a prion- like manner after peripheral administration. EMBO Report, 5;23(7):e54405. IF- 6.2, DOI: 10.15252/embr.202154405
S Mehra, S Ahlawat, H Kumar, D Datta, A Navalkar, N Singh, K Patel, L Gadhe, P Kadu, R Kumar, NN Jha, A Sakunthala, AS Sawner, R Padinhateeri, JB Udgaonkar, V Agarwal, SK Maji (2022). α-Synuclein aggregation intermediates form fibril polymorphs with distinct prion-like properties. Journal of Molecular Biology, 167761. IF- 4.5, DOI: 10.1016/j.jmb.2022.167761
A Sakunthala, D Datta, A Navalkar, L Gadhe, P Kadu, K Patel, S Mehra, R Kumar, D Chatterjee, J Devi, K Sengupta, R Padinhateeri, SK Maji (2022). Direct Demonstration of Seed Size-Dependent α- Synuclein Amyloid Amplification. Journal of Physical Chemistry Letters, 13, 28, 6427–6438. IF- 4.7, DOI: 10.1021/acs.jpclett.2c01650
T Arndt, K Jaudzems, O Shilkova, J Francis, M Johansson, PR Laity, C Sahin, U Chatterjee, N Kronqvist, EB Ledesma, R Kumar, G Chen, R Strömberg, A Abelein, M Langton, M Landreh, A Barth, C Holland, J Johansson and A Rising (2022). Spidroin N-terminal domain forms amyloid-like fibril-based hydrogels and provides a protein immobilization platform. Nature Communications 13, Article number: 4695. IF- 15.7, DOI: 10.1038/s41467-022- 32093-7
N Pravin #, R Kumar #, S Tripathi, P Kumar, GM Mohite, A Navalkar, R Panigrahi, N Singh, LG Gadhe, S Manchanda, M Shimozawa, P Nilsson, J Johansson, A Kumar, SK Maji, M Shanmugam (2020). Benzimidazole based fluorophores for the detection of amyloid fibrils with higher sensitivity than Thioflavin-T. (# Equally contributed author), Journal of Neurochemistry, 156:1003–1019. IF- 4, DOI: 10.1111/jnc.15138
S Ray, N Singh, R Kumar, K Patel, S Pandey, D Datta, J Mahato, R Panigrahi, A Navalkar, S Mehra, L Gadhe, D Chatterjee, AS Sawner, S Maiti, S Bhatia, JA Gerez, A Chowdhury, A Kumar, R Padinhateeri, R Riek, G Krishnamoorthy, SK Maji (2020). Alpha-Synuclein aggregation nucleates through liquid-liquid phase separation. Nature Chemistry, 12, 705– 716. IF- 20.2, DOI: 10.1038/s41557-020-0465-9
H Biverstål, R Kumar, AK Schellhaus, M Sarr, NP Dantuma, A Abelein & J Johansson (2020). Functionalization of amyloid fibrils via the Bri2 BRICHOS domain. Nature Scientific Report, 10, 21765. IF- 3.9, DOI: 10.1038/s41598-020-78732-1
K Sharma, S Mehra, AS Sawner, PS Markam, R Panigrahi, A Navalkar, D Chatterjee, R Kumar, P Kadu, K Patel, S Ray, A Kumar, SK Maji (2020). Effect of disease-associated P123H and V70M mutations on beta-synuclein fibrillation. ACS chemical Neuroscience, 11, 18, 2836–2848. IF- 3.9, DOI: 10.1021/acschemneuro.0c00405
P Kadu, S Pandey, S Neekhra, R Kumar, L Gadhe, R Srivastava, M Sastry, S K Maji (2020). Machine free PCR with triangular gold and silver nanoparticles. The Journal of Physical Chemistry Letters, 11, 24, 10489–10496. IF- 4.7, DOI: 10.1021/acs.jpclett.0c02708
R Jayarajan #, R Kumar #, J Gupta, G Dev, P Kadu, D Chatterjee, D Bahadur, D Maiti and S K Maji (2019). Fabrication of amyloid fibril-palladium nanocomposite: A sustainable catalyst for C–H activation and electrooxidation of ethanol (# Equally contributed author). Journal of Material Chemistry A, 7, 4486-4493, IF- 9.5 (* included in PhD dissertation). DOI: 10.1039/c8ta11134k
D Bhattacharyya, GM Mohite, J Krishnamoorthy, N Gayen, S Mehera, A Navalkar, SA Kotler, BN Ratha, A Ghosh, R Kumar, K Garai, AK Mandal, SK Maji, and A Bhunia (2019). Lipopolysaccharide from gut microbiota modulates α-Synuclein aggregation and alters its biological function. ACS Chemical Neuroscience,10,2229-2234. IF- 3.9, DOI: 10.1021/acschemneuro.8b00733
S Kirti, K Patel, S Das, P Shrimali, S Samanta, R Kumar, D Chatterjee, D Ghosh, A Kumar, P Tayalia and SK Maji (2019). Amyloid Fibrils with Positive Charge Enhance Retroviral Transduction in Mammalian Cells. ACS Biomaterials Science and Engineering, 5, 1, 126- 138. IF- 5.5, DOI: 10.1021/acsbiomaterials.8b00248
R Kumar, S Das, GM Mohite, SK Rout, S Halder, NN Jha, S Mehra, V Agarwal, and SK Maji (2018). Cytotoxic Oligomers and Fibrils Trapped in a Gel-like State of α-Synuclein Assemblies. Angewandte Chemie International edition, 57(19):5262–5266, IF-16.9 (* included in PhD dissertation). DOI: 10.1002/anie.201711854
GM Mohite, # R Kumar #, R Panigrahi, A Navalkar, N Singh, D Datta, S Mehra, S Ray, LG Gadhe, S Das, N Singh, D Chatterjee, A Kumar, and SK Maji (2018). Comparison of Kinetics, Toxicity, Oligomer Formation, and Membrane Binding Capacity of α-Synuclein Familial Mutations at the A53 Site, Including the Newly Discovered A53V Mutation (# equally contributed author), Biochemistry, 57(35):5183-5187. This article was selected for “Cover Page” of journal. IF-3, DOI: 10.1021/acs.biochem.8b00314
GM Mohite, A Navalkar, R Kumar, S Mehra, S Das, LG Gadhe, D Ghosh, B Alias, V Chandravanshi, A Ramakrishnan, S Mehra and SK Maji (2018). Familial α-Synuclein A53E Mutation Enhances Cell Death in Response to Environmental Toxins due to More Population of Oligomers. Biochemistry, 57(33):5014-5028. IF- 3, DOI: 10.1021/acs.biochem.8b00321
S Mehra, D Ghosh, R Kumar, M Mondal, LG Gadhe, S Das, A Anoop, NN Jha, RS Jacob, D Chatterjee, S Ray, N Singh, A Kumar, and SK Maji (2018). Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils. Journal of Biological Chemistry, 293(34): 12975-12991. This article was selected as “Cover Page” of journal. IF- 3.9, DOI: 10.1074/jbc.ra118.004267
S Das, MK Kumawat, S Ranganathan, R Kumar, J Adamcik, P Kadu, R Paadinhaateri, R Srivastava, R Mezzenga and SK Maji (2018). Cell alignment on graphene-amyloid composites. Advanced Materials Interfaces, 1800621. IF- 4.9, DOI: 10.1002/admi.201800621
D Bhattacharyya, R Kumar, S Mehra, Anirban Ghosh, SK Maji and A Bhunia (2018). Multitude NMR Studies of α-Synuclein Familial Mutants: Probing Their Differential Aggregation Propensities. Chemical Communications, 54:3605-3608. IF- 4.2, DOI: 10.1039/c7cc09597j
GM Mohite, S Dwivedi, S Das, R Kumar, S Paluri, S Mehra, N Ruhela, A Sakunthala, NN Jha, and SK Maji (2018). Parkinson’s Disease Associated α-Synuclein Familial Mutants Promote Dopaminergic Neuronal Death in Drosophila melanogaster. ACS Chemical Neuroscience, 9(11):2628-2638. IF- 3.9, DOI: 10.1021/acschemneuro.8b00107
NN Jha, S Ranganathan, R Kumar, S Mehra, R Panigrahi, A Navalkar, D Ghosh, A Kumar, R Padinhateeri and SK Maji (2018). Complexation of NAC derived peptide ligands with C terminus of α- synuclein accelerates its aggregation. Biochemistry, 57(5): 791-804. IF- 3, DOI: 10.1021/acs.biochem.7b01090
S Das, R Kumar, NN Jha, SK Maji (2017). Controlled exposure of bio-active growth factor in 3D amyloid hydrogel for stem cells differentiation. Advanced Healthcare Materials, 6(18):1700368. This article was selected for “Cover Page” of journal. IF- 9.6, DOI: 10.1002/adhm.201700368
NN Jha, R Kumar, R Panigrahi, A Navalkar, D Ghosh, S Sahay, M Mondal, A Kumar and SK Maji (2017). Comparison of α-synuclein fibril inhibition by four different amyloid inhibitors. ACS Chemical Neuroscience, 8(12): 2722-2733. IF- 3.9, DOI: 10.1021/acschemneuro.7b00261
S Ghosh, S Salot, S Sengupta, A Navalkar, D Ghosh, RS Jacob, S Das, R Kumar, NN Jha, S Sahay, S Mehra, GM Mohite, SK Ghosh, M Kombrabail, G Krishnamoorthy, P Chaudhari, and SK Maji (2017). p53 amyloid formation leading to its loss of function: Implications in cancer pathogenesis. Cell Death and Differentiation, 24(10):1784–1798. IF- 15.4, DOI: 10.1038/cdd.2017.105