Peer Reviewed publications:
R Kumar, S Gravett, V Jelic, J Lange, L Oftedal, A Ciullini, M B Bacınoğlu, C M Giulia De Luca, L Hamied, C Birck, F Blanc, P L Hoede, A W Lemstra, M C Gonzalez, D Aarsland, C E Teunissen, Oliver Bousiges, Fabio Moda, J Maple-Grødem, A Abelein, and D Ferreira. Diagnostic Performance of the Alpha-Synuclein Seed Amplification Assay for Dementia with Lewy Bodies: A comparison across four laboratories. Neurology, 2025, Impact factor ( IF) , 9.00, Accepted, 2025.
Zhen Jin#, William Pallisgaard Olsen#, Cecilia Mörman#, Rakesh Kumar#, Axel Leppert, Lotte Godthaab Nielsen, Jokin Yeregui Elosua, Axel Abelein, Michael Landreh, Stefan Knight, Jan Johansson, Daniel E. Otzen and Gefei Chen (2025). The protein CagA released by Helicobacter pylori is a potent and broad-spectrum amyloid inhibitor (# Equally contributed author). Science Advances, 11, eads7525, IF- 12.5, DOI: 10.1126/sciadv.ads7525
C Mörman, A Leppert, G Pizzirusso, Z Zheng, X SunKuma, R Kumar, H Biverstål, M Landreh, J Johansson, L Arroyo García, J Luo, G Chen and A Abelein (2025). Chaperone Mediated Regulation of Tau Phase Separation, Fibrillation and Toxicity. Journal of the American Chemical Society,147, 27, 23504–23518, IF- 15.7, DOI: 10.1021/jacs.5c01369
R Kumar, T L Marchand, L Adam, R Bobrovs, G Chen, J Fridmanis, N Kronqvist, H Biverstål, K Jaudzems, J Johansson, G Pintacuda and A Abelein (2024). Identification of aggregation hotspots on Aβ42 fibrils blocked by an anti-amyloid chaperone-like domain. Nature Communication 15, 965, IF- 15.7, https://doi.org/10.1038/s41467- 024-45192-4
L Adam, R Kumar, LE Arroyo-Garcia, WH Molenkamp, JS Nowak, H Klute, A Farzadfard, R Alkenayeh, J Nielsen, H Biverstål, DE Otzen, J Johansson, A Abelein (2024). Specific inhibition of α-synuclein oligomer generation and toxicity by the chaperone domain Bri2 BRICHOS. Protein Science. 33(8):e5091. IF 5.2, DOI: 10.1002/pro.5091.
R Kumar, LEA García, S Manchanda, L Adam, Giusy Pizzirusso, Henrik Biverstål, P Nilsson, Andrè Fisahn, J Johansson and A Abelein (2023). Molecular mechanisms of amyloid-β self-assembly seeded by in vivo derived fibrils and inhibitory effects of the BRICHOS chaperone. ACS Chemical Neuroscience, 14, 8, 1503–1511, IF- 3.9, DOI: 10.1021/acschemneuro.3c00044
C Peña-Bautista, R Kumar, M Baquero, C, Chafer-Pericas, A Abelein, D Ferreira (2023). Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis. Frontier Molecular Bioscience. 10:1193458. IF- 4, DOI: 10.3389/fmolb.2023.1193458
A Abelein, S Ciofi, C Mörman, R Kumar, A Giachetti, M Piccioli, and H Biverstål (2022). Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer’s Disease. Journal of the American Chemical Society Au, 2(11): 2571–2584, IF- 8.7, DOI: 10.1021/jacsau.2c00438
X Zhong, R Kumar, Y Wang, H Biverstål, C I Jegerschöld, P J B Koeck, J Johansson, A Abelein, and G Chen (2022). Amyloid Fibril Formation of Arctic Amyloid-β 1-42 Peptide is Efficiently Inhibited by the BRICHOS Domain. ACS Chemical Biology, 17, 8, 2201–2211. IF- 3.8, DOI: 10.1021/acschembio.2c00344
R Jiang, M Shimozawa, J Mayer, S Tambaro, R Kumar, A Abelein, B Winblad, N Bogdanovic, P Nilsson (2022). Autophagy Impairment in App Knock-in Alzheimer's Model Mice. Frontiers Aging Neuroscience, 14:878303. IF- 4.5, DOI: 10.3389/fnagi.2022.878303
P Kadu, L Gadhe, A Navalkar, K Patel, R Kumar, M Sastry and SK Maji (2022). Charge and hydrophobicity of amyloidogenic protein/peptide templates regulate the growth and morphology of gold nanoparticles. Nanoscale, 14, 15021-15033. IF - 5.1, DOI: 10.1039/d2nr01942f
M Brackhan, G Calza, K Lundgren, P Bascuñana, T Brüning, R Soliymani, R Kumar, A Abelein, M Baumann, M Lalowski, J Pahnke (2022). Isotope-labeled amyloid-β does not transmit to the brain in a prion- like manner after peripheral administration. EMBO Report, 5;23(7):e54405. IF- 6.2, DOI: 10.15252/embr.202154405
S Mehra, S Ahlawat, H Kumar, D Datta, A Navalkar, N Singh, K Patel, L Gadhe, P Kadu, R Kumar, NN Jha, A Sakunthala, AS Sawner, R Padinhateeri, JB Udgaonkar, V Agarwal, SK Maji (2022). α-Synuclein aggregation intermediates form fibril polymorphs with distinct prion-like properties. Journal of Molecular Biology, 167761. IF- 4.5, DOI: 10.1016/j.jmb.2022.167761
A Sakunthala, D Datta, A Navalkar, L Gadhe, P Kadu, K Patel, S Mehra, R Kumar, D Chatterjee, J Devi, K Sengupta, R Padinhateeri, SK Maji (2022). Direct Demonstration of Seed Size-Dependent α- Synuclein Amyloid Amplification. Journal of Physical Chemistry Letters, 13, 28, 6427–6438. IF- 4.7, DOI: 10.1021/acs.jpclett.2c01650
T Arndt, K Jaudzems, O Shilkova, J Francis, M Johansson, PR Laity, C Sahin, U Chatterjee, N Kronqvist, EB Ledesma, R Kumar, G Chen, R Strömberg, A Abelein, M Langton, M Landreh, A Barth, C Holland, J Johansson and A Rising (2022). Spidroin N-terminal domain forms amyloid-like fibril-based hydrogels and provides a protein immobilization platform. Nature Communications 13, Article number: 4695. IF- 15.7, DOI: 10.1038/s41467-022- 32093-7
N Pravin #, R Kumar #, S Tripathi, P Kumar, GM Mohite, A Navalkar, R Panigrahi, N Singh, LG Gadhe, S Manchanda, M Shimozawa, P Nilsson, J Johansson, A Kumar, SK Maji, M Shanmugam (2020). Benzimidazole based fluorophores for the detection of amyloid fibrils with higher sensitivity than Thioflavin-T. (# Equally contributed author), Journal of Neurochemistry, 156:1003–1019. IF- 4, DOI: 10.1111/jnc.15138
S Ray, N Singh, R Kumar, K Patel, S Pandey, D Datta, J Mahato, R Panigrahi, A Navalkar, S Mehra, L Gadhe, D Chatterjee, AS Sawner, S Maiti, S Bhatia, JA Gerez, A Chowdhury, A Kumar, R Padinhateeri, R Riek, G Krishnamoorthy, SK Maji (2020). Alpha-Synuclein aggregation nucleates through liquid-liquid phase separation. Nature Chemistry, 12, 705– 716. IF- 20.2, DOI: 10.1038/s41557-020-0465-9
H Biverstål, R Kumar, AK Schellhaus, M Sarr, NP Dantuma, A Abelein & J Johansson (2020). Functionalization of amyloid fibrils via the Bri2 BRICHOS domain. Nature Scientific Report, 10, 21765. IF- 3.9, DOI: 10.1038/s41598-020-78732-1
K Sharma, S Mehra, AS Sawner, PS Markam, R Panigrahi, A Navalkar, D Chatterjee, R Kumar, P Kadu, K Patel, S Ray, A Kumar, SK Maji (2020). Effect of disease-associated P123H and V70M mutations on beta-synuclein fibrillation. ACS chemical Neuroscience, 11, 18, 2836–2848. IF- 3.9, DOI: 10.1021/acschemneuro.0c00405
P Kadu, S Pandey, S Neekhra, R Kumar, L Gadhe, R Srivastava, M Sastry, S K Maji (2020). Machine free PCR with triangular gold and silver nanoparticles. The Journal of Physical Chemistry Letters, 11, 24, 10489–10496. IF- 4.7, DOI: 10.1021/acs.jpclett.0c02708
R Jayarajan #, R Kumar #, J Gupta, G Dev, P Kadu, D Chatterjee, D Bahadur, D Maiti and S K Maji (2019). Fabrication of amyloid fibril-palladium nanocomposite: A sustainable catalyst for C–H activation and electrooxidation of ethanol (# Equally contributed author). Journal of Material Chemistry A, 7, 4486-4493, IF- 9.5 (* included in PhD dissertation). DOI: 10.1039/c8ta11134k
D Bhattacharyya, GM Mohite, J Krishnamoorthy, N Gayen, S Mehera, A Navalkar, SA Kotler, BN Ratha, A Ghosh, R Kumar, K Garai, AK Mandal, SK Maji, and A Bhunia (2019). Lipopolysaccharide from gut microbiota modulates α-Synuclein aggregation and alters its biological function. ACS Chemical Neuroscience,10,2229-2234. IF- 3.9, DOI: 10.1021/acschemneuro.8b00733
S Kirti, K Patel, S Das, P Shrimali, S Samanta, R Kumar, D Chatterjee, D Ghosh, A Kumar, P Tayalia and SK Maji (2019). Amyloid Fibrils with Positive Charge Enhance Retroviral Transduction in Mammalian Cells. ACS Biomaterials Science and Engineering, 5, 1, 126- 138. IF- 5.5, DOI: 10.1021/acsbiomaterials.8b00248
R Kumar, S Das, GM Mohite, SK Rout, S Halder, NN Jha, S Mehra, V Agarwal, and SK Maji (2018). Cytotoxic Oligomers and Fibrils Trapped in a Gel-like State of α-Synuclein Assemblies. Angewandte Chemie International edition, 57(19):5262–5266, IF-16.9 (* included in PhD dissertation). DOI: 10.1002/anie.201711854
GM Mohite, # R Kumar #, R Panigrahi, A Navalkar, N Singh, D Datta, S Mehra, S Ray, LG Gadhe, S Das, N Singh, D Chatterjee, A Kumar, and SK Maji (2018). Comparison of Kinetics, Toxicity, Oligomer Formation, and Membrane Binding Capacity of α-Synuclein Familial Mutations at the A53 Site, Including the Newly Discovered A53V Mutation (# equally contributed author), Biochemistry, 57(35):5183-5187. This article was selected for “Cover Page” of journal. IF-3, DOI: 10.1021/acs.biochem.8b00314
GM Mohite, A Navalkar, R Kumar, S Mehra, S Das, LG Gadhe, D Ghosh, B Alias, V Chandravanshi, A Ramakrishnan, S Mehra and SK Maji (2018). Familial α-Synuclein A53E Mutation Enhances Cell Death in Response to Environmental Toxins due to More Population of Oligomers. Biochemistry, 57(33):5014-5028. IF- 3, DOI: 10.1021/acs.biochem.8b00321
S Mehra, D Ghosh, R Kumar, M Mondal, LG Gadhe, S Das, A Anoop, NN Jha, RS Jacob, D Chatterjee, S Ray, N Singh, A Kumar, and SK Maji (2018). Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils. Journal of Biological Chemistry, 293(34): 12975-12991. This article was selected as “Cover Page” of journal. IF- 3.9, DOI: 10.1074/jbc.ra118.004267
S Das, MK Kumawat, S Ranganathan, R Kumar, J Adamcik, P Kadu, R Paadinhaateri, R Srivastava, R Mezzenga and SK Maji (2018). Cell alignment on graphene-amyloid composites. Advanced Materials Interfaces, 1800621. IF- 4.9, DOI: 10.1002/admi.201800621
D Bhattacharyya, R Kumar, S Mehra, Anirban Ghosh, SK Maji and A Bhunia (2018). Multitude NMR Studies of α-Synuclein Familial Mutants: Probing Their Differential Aggregation Propensities. Chemical Communications, 54:3605-3608. IF- 4.2, DOI: 10.1039/c7cc09597j
GM Mohite, S Dwivedi, S Das, R Kumar, S Paluri, S Mehra, N Ruhela, A Sakunthala, NN Jha, and SK Maji (2018). Parkinson’s Disease Associated α-Synuclein Familial Mutants Promote Dopaminergic Neuronal Death in Drosophila melanogaster. ACS Chemical Neuroscience, 9(11):2628-2638. IF- 3.9, DOI: 10.1021/acschemneuro.8b00107
NN Jha, S Ranganathan, R Kumar, S Mehra, R Panigrahi, A Navalkar, D Ghosh, A Kumar, R Padinhateeri and SK Maji (2018). Complexation of NAC derived peptide ligands with C terminus of α- synuclein accelerates its aggregation. Biochemistry, 57(5): 791-804. IF- 3, DOI: 10.1021/acs.biochem.7b01090
S Das, R Kumar, NN Jha, SK Maji (2017). Controlled exposure of bio-active growth factor in 3D amyloid hydrogel for stem cells differentiation. Advanced Healthcare Materials, 6(18):1700368. This article was selected for “Cover Page” of journal. IF- 9.6, DOI: 10.1002/adhm.201700368
NN Jha, R Kumar, R Panigrahi, A Navalkar, D Ghosh, S Sahay, M Mondal, A Kumar and SK Maji (2017). Comparison of α-synuclein fibril inhibition by four different amyloid inhibitors. ACS Chemical Neuroscience, 8(12): 2722-2733. IF- 3.9, DOI: 10.1021/acschemneuro.7b00261
S Ghosh, S Salot, S Sengupta, A Navalkar, D Ghosh, RS Jacob, S Das, R Kumar, NN Jha, S Sahay, S Mehra, GM Mohite, SK Ghosh, M Kombrabail, G Krishnamoorthy, P Chaudhari, and SK Maji (2017). p53 amyloid formation leading to its loss of function: Implications in cancer pathogenesis. Cell Death and Differentiation, 24(10):1784–1798. IF- 15.4, DOI: 10.1038/cdd.2017.105