Our Lab investigate fundamental and translational research questions in neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Amyotrophic Lateral Sclerosis (ALS). Our work integrates protein biochemistry and protein engineering principles to address key molecular mechanisms underlying disease progression.

A major focus of our research is the inhibition of pathological protein aggregation, where we explore the roles of small molecules, molecular chaperones, and therapeutic compounds as potential modulators of disease-associated proteins.

We also have a strong interest in the discovery and validation of biomarkers from blood, plasma, and cerebrospinal fluid (CSF) to improve disease diagnosis and to better understand disease mechanisms in neurodegenerative disorders.

In addition, we aim to elucidate the role of amyloid formation in viral-associated diseases, including its potential contribution to cervical cancer, thereby extending our research beyond classical neurodegeneration into broader disease contexts.