Publications

Publications

# equal contribution * corresponding author

Richa Rikhy ORCID 0000-0002-4262-0238

• Bhavin Uttekar, Darshika Tomer and Richa Rikhy* (2024). Mitochondrial morphology dynamics and ROS regulate apical polarity and differentiation in Drosophila follicle cells; https://www.biorxiv.org/content/10.1101/2023.03.10.532033v1, Development (accepted for publication)

• Bipasha Dey#, Debasmita Mitra#, Tirthasree Das, Aparna Sherlekar, Ramya Balaji, Richa Rikhy* (2023). Polarity protein distribution on the metaphase furrow regulates hexagon dominated plasma membrane organization in syncytial Drosophila embryos. bioRxiv 770453; doi: https://doi.org/10.1101/770453, Genetics (in press) https://doi.org/10.1093/genetics/iyad184

• Stavroula Petridi#, Dnyanesh Duba#l, Richa Rikhy*, and Jelle van den Ameele* (2022). Mitochondrial respiration and dynamics of in vivo neural stem cells. Development, https://doi.org/10.1242/dev.200870 

• Debasmita Mitra, Amruta Swaminathan, Gayatri Mundhe and Richa Rikhy* (2022). Imaging and quantification of apical microvilli in the syncytial blastoderm of Drosophila embryos. Star Protocols, DOI: 10.1016/j.xpro.2022.10173.

• Sameer Thukral, Bivash Kaity, Debasmita Mitra, Bipasha Dey, Pampa Dey, Bhavin Uttekar, Mithun K. Mitra*, Amitabha Nandi* and Richa Rikhy* (2022). Pseudocleavage furrows restrict plasma membrane associated PH domain in syncytial Drosophila embryos. Biophysical Journal, https://doi.org/10.1016/j.bpj.2022.05.015. 

• Swati Sharma and Richa Rikhy* (2022). Measurement of contractile ring tension using two-photon laser ablation in Drosophila cellularization. Bio-protocol  doi:10.21769/BioProtoc.4362.

• Dnyanesh Dubal, Prachiti Moghe*, Rahul Kumar Verma*, Bhavin Uttekar and Richa Rikhy* (2022). Mitochondrial fusion regulates proliferation and differentiation in the type II neuroblast lineage in Drosophila. PLOS Genetics, https://doi.org/10.1371/journal.pgen.1010055,  https://biorxiv.org/cgi/content/short/2021.01.08.425832v1. *equal contribution

• Somya Madan#, Bhavin Uttekar#, Sayali Chowdhary# and Richa Rikhy* (2022). Mitochondria lead the way: mitochondrial dynamics and function in cellular movements in development and disease. Frontiers in Cell and Developmental Biology, .https://doi.org/10.3389/fcell.2021.781933.

• Sayali Chowdhary and Richa Rikhy* (2022) Labeling and tracking mitochondria with photoactivation in Drosophila embryos. Bio-protocol, Vol 12, Iss 3, March 05, 2022, doi: 10.21769/BioProtoc.4347.

• Swati Sharma and Richa Rikhy* (2021).  Spatiotemporal recruitment of RhoGTPase protein GRAF inhibits actomyosin ring constriction in Drosophila cellularization. eLife https://elifesciences.org/articles/63535

  • • Swati Sharma got selected for best paper in Lifesciences in India by Inspiring Science Award-TNQ technologies for 2021-2022 https://www.tnq.co.in/inspiring-science-award/2022.php

    • See the award ceremony video here https://www.youtube.com/watch?v=MLODrF55DyM 

• Sayali Chowdhary, Somya Madan, Darshika Tomer,  Manos Mavrakis and Richa Rikhy* (2020). Mitochondrial morphology and activity regulate furrow ingression and contractile ring dynamics in Drosophila cellularization. Molecular Biology of the Cell (https://www.molbiolcell.org/doi/abs/10.1091/mbc.E20-03-0177).

• Sameer Thukral, Bivash Kaity, Bipasha Dey, Swati Sharma, Amitabha Nandi, Mithun Mitra, Richa Rikhy* (2020). Cyto-architecture constrains the spread of photoactivated tubulin in the syncytial Drosophila embryo. bioRxiv 520031; doi: https://doi.org/10.1101/520031, International Journal of Developmental Biology 64: 265-277.

• Aparna Sherlekar, Gayatri Mundhe#, Prachi Richa#, Bipasha Dey, Swati Sharma and Richa Rikhy* (2020). F-BAR domain protein Syndapin regulates actomyosin dynamics during apical cap remodeling in syncytial Drosophila embryos. Journal of Cell Science, https://jcs.biologists.org/content/early/2020/04/21/jcs.235846, * equal contribution

• Bipasha Dey and Richa Rikhy* (2020). DE-cadherin and Myosin II balance regulates furrow length for onset of polygon shape in syncytial Drosophila embryos. Journal of Cell Science, https://jcs.biologists.org/content/early/2020/04/06/jcs.240168

  • • • Associated with First Person interview for Bipasha Dey at https://jcs.biologists.org/content/133/10/jcs247429

• Tomer D, Chippalkatti R, Mitra K and Rikhy R*. (2018) ERK regulates mitochondrial membrane potential in fission deficient Drosophila follicle cells during differentiation. Developmental Biology, Dev Biol. Feb 1;434(1):48-62. Selected for cover page.

• Chowdhary S, Tomer D, Dnyanesh D, Sambre D and Rikhy R*. (2017) Analysis of mitochondrial organization and function in the Drosophila blastoderm embryo. Nature Scientific Reports Jul 14;7(1):5502. doi: 10.1038/s41598-017-05679-1.  (Selected for Top 100 in Cell Biology)

• Sherlekar A and Rikhy R*. (2017) Syndapin bridges the membrane-cytoskeleton divide during furrow extension. Communicative and Integrative Biology 2017; 10(1): e1255832.

• Sherlekar A and Rikhy R*. (2016) Syndapin promotes pseudocleavage furrow formation by actin organization in the syncytial Drosophila embryo. Molecular Biology of the Cell Jul 1;27(13):2064-79. 

• Rikhy R*, Mavrakis M and Lippincott-Schwartz J*. (2015) Dynamin regulates metaphase furrow formation and plasma membrane compartmentalization in the syncytial Drosophila embryo. Biol Open Feb 6;4(3):301-11. 

• Rikhy R, Kumar V, Basole A and Sanyal S*. (2015) Remembering K.S. Krishnan (1946-2014). Journal of Neurogenetics Mar; 29(1):1-3.    

• Daniels BR, Rikhy R, Renz M, Dobrowsky TM and Lippincott-Schwartz J*. (2012) Multiscale diffusion in mitotic Drosophila syncytial blastoderm Proceedings of the National Academy of Sciences USA 2012 May 29; 109(22):8588-93.

• Sherlekar A, Rikhy R*. (2012) Drosophila embryo syncytial blastoderm cellular architecture and morphogen gradient dynamics: Is there a correlation? Frontiers in Biology, 7,1:73-82.

Before IISER, Pune

• Mitra K*, Rikhy R*, Lilly M, and Lippincott-Schwartz J. (2012). DRP1-dependent mitochondrial fission initiates follicle cell differentiation during Drosophila oogenesis. * equal contribution J Cell Biol. 197(4):487-97. 

• Kanodia JS, Rikhy R, Kim Y, Lund VK, Delotto R, Lippincott-Schwartz J, Schvartsman SY. 2009 Dynamics of the Dorsal Gradient. Proceedings of the National Academy of Sciences USA Dec 22;106(51):21707-12.

• Chua J, Rikhy R and Lippincott-Schwartz J. (2009) Dynamin’s function in apical constriction Proceedings of the National Academy of Sciences USA, Dec 8;106(49):20770-5.

• Mavrakis M, Rikhy R and Lippincott-Schwartz. (2009) Cells within a cell: insights into cellular architecture and polarization from the organization of the early fly embryo Communicative and integrated biology, Jul;2(4):313-4

• Mavrakis M, Rikhy R and Lippincott-Schwartz J. (2009) Plasma Membrane Polarity and compartmentalization are established prior to cellularization in the Fly Embryo Developmental Cell, 16(1):93-104.

• Mavrakis M, Rikhy R, Lilly M, Lippincott-Schwartz J. (2008) Fluorescence imaging techniques for studying Drosophila embryo development, Current protocols in Cell biology, Chapter 4: Unit 4.18. 

• Rikhy R, Kamat S, Ramagiri S, Sriram V, Krishnan KS. (2007) Mutations in Dynamin Related Protein result in gross changes in mitochondrial morphology and affect synaptic vesicle recycling at the Drosophila Neuromuscular Junction. Genes Brain and Behavior, 6:42-53.

• Suseendranathan K*, Sengupta K*, Rikhy R, D'Souza JS, Kokkanti M, Kulkarni MG, Kamdar R, Changede R, Sinha R, Subramanian L, Singh K, Rodrigues V, Rao BJ (2007) Expression pattern of Drosophila translin and behavioral analyses of the mutant. Eur J Cell Biol. 86:173-86. * equal contribution

• Majumdar A, Ramagiri SV and Rikhy R. (2006) Drosophila homologue of Eps15 is essential for synaptic vesicle recycling. Exp Cell Res. 312:2288-98. 

• Rikhy R, Krishnan KS (2003) A synaptic detour to cellular traffic Proc. Indian Natn. Sci. Acad. 69: 587-624.

• Rikhy R, Ramaswami M, Krishnan KS. (2003) A genetic modifier of shibire in Mitochondrial Adenine Nucleotide Translocase locus has a temperature sensitive paralytic phenotype, Genetics; 165:1243-53.

• Rikhy R*, Kumar V*, Mittal R, Krishnan KS. (2002) Endophilin is critically required for synapse formation and function in Drosophila melanogaster. J Neurosci. 22:7478-84. * equal contribution

• Krishnan KS, Rikhy R, Rao S, Shivalkar M, Mosko M, Narayan RK, Estes P, Ramaswami M. (2001) Nucleoside diphosphate kinase, a source of GTP, is required for dynamin-dependent synaptic vesicle recycling. Neuron 30: 197-210.

About the lab and general articles

• Richa Rikhy as a new editor in Journal of Cell Science.

• Making Cellular Art with Richa, Life of Science, Aashima Dogra

• Mitochondria: Where do they come from and where do they take us? Science Trends, Richa Rikhy

• 31 Fantastic Adventures in Science: Women Scientists in India, Penguin Books, Nandita Jayraj, Aashima Dogra

• Fly in Space by Aashima Dogra and Fahad Faizal at Story Weaver

• Mitochondria in fruit fly embryogenesis, round, dynamic and active by Sapna Chhabra, Research Matters