Publication

2026

Reproducibility of OCT Radiomics after Cataract Surgery: Effects of Media Opacity, Signal strength, and ROI selection.

Kim NH, Kim HM, Chung H, Lee H.

Korean J Ophthalmol. 2026 Feb 19. doi: 10.3341/kjo.2025.0149. Online ahead of print.

PMID: 41709581

2025

In vivo efficacy of NRL knockdown with cell-penetrating siRNA in retinal degeneration.

Lee H, Jang H, Chae JB, Lee HK, Son C, Park CW, Ha T, Yum M, Park S, Hong SW, Lee SY, Lyu J, Lee S, Lee DK, Chung H.

Sci Rep. 2025 Jul 26;15(1):27176. doi: 10.1038/s41598-025-07299-6.

PMID: 40715177

Prospective evaluation of soluble CD14 as a biomarker following five aflibercept treatments in diabetic macular edema.

Lee H, Lee M, Kim N, Kim N, Moon D, Son C, Chung H.

Sci Rep. 2025 May 16;15(1):17080. doi: 10.1038/s41598-025-93472-w.

PMID: 40379891

Deep-Learning Method for the Diagnosis and Classification of Orbital Blowout Fracture Based on Computed Tomography.

Kim S, Koh HK, Lee H, Shin HJ.

J Oral Maxillofac Surg. 2025 Aug;83(8):980-989. doi: 10.1016/j.joms.2025.04.010. Epub 2025 Apr 23.

PMID: 40349723

GENERATIVE DEEP LEARNING APPROACH TO PREDICT POSTTREATMENT OPTICAL COHERENCE TOMOGRAPHY IMAGES OF AGE-RELATED MACULAR DEGENERATION AFTER 12 MONTHS.

Lee H, Kim N, Kim NH, Chung H, Kim HC.

Retina. 2025 Jun 1;45(6):1184-1191. doi: 10.1097/IAE.0000000000004409.

PMID: 39841905

2024

Using Artificial Intelligence to Diagnose Lacrimal Passage Obstructions Based on Dacryocystography Images.

Kim S, Lee H, Roh HG, Shin HJ.

J Craniofac Surg. 2025 Mar-Apr 01;36(2):595-599. doi: 10.1097/SCS.0000000000010829. Epub 2024 Nov 6.

PMID: 39504416 

Correlation between subretinal tissue plasminogen activator and air injection rates with pressure in a retina mimicking model.

Kim NH, Lee M, Chung H, Kim HC, Lee H.

Sci Rep. 2024 Oct 31;14(1):26203. doi: 10.1038/s41598-024-77518-z.

PMID: 39482440 

Prediction of Post-Treatment Visual Acuity in Age-Related Macular Degeneration Patients With an Interpretable Machine Learning Method.

Kim N, Lee M, Chung H, Kim HC, Lee H.

Transl Vis Sci Technol. 2024 Sep 3;13(9):3. doi: 10.1167/tvst.13.9.3.

PMID: 39226064 

Initial Factors Associated with Resistance to Intravitreal Aflibercept Injection in Polypoidal Choroidal Vasculopathy

Dayoung Moon, Minsub Lee, Hyewon Chung, Hyungwoo Lee

J Korean Ophthalmol Soc. 2024;65(7):425-434.  

2023

Post-treatment Visual Acuity Prediction Using Deep Learning in Age-related Macular Degeneration

N Kim, HC Kim, H Chung, H Lee

Journal of the Korean Ophthalmological Society 64 (7), 582-590

Supramolecular Senolytics via Intracellular Oligomerization of Peptides in Response to Elevated Reactive Oxygen Species Levels in Aging Cells.

Kim S, Chae JB, Kim D, Park CW, Sim Y, Lee H, Park G, Lee J, Hong S, Jana B, Kim C, Chung H, Ryu JH.

J Am Chem Soc. 2023 Oct 11;145(40):21991-22008. doi: 10.1021/jacs.3c06898. Epub 2023 Sep 4.

PMID: 37664981

The Bcl-2/Bcl-xL Inhibitor ABT-263 Attenuates Retinal Degeneration by Selectively Inducing Apoptosis in Senescent Retinal Pigment Epithelial Cells.

Ryu W, Park CW, Kim J, Lee H, Chung H.

Mol Cells. 2023 Jul 31;46(7):420-429. doi: 10.14348/molcells.2023.2188. Epub 2023 May 24.

PMID: 37222160 

Risk of Retinopathy in Women with Pregnancy-induced Hypertension: A nationwide population-based cohort study of 9-year follow-up after delivery.

Lee H*, Yang SW*, Kim Y, Shin H, Seo YS, Jeong M, Choi S, Cho GJ, Hwang HS.

Am J Obstet Gynecol MFM. 2023 Apr 27:100985. doi: 10.1016/j.ajogmf.2023.100985. Online ahead of print.

*Co-first authors 

Association between glycemic status and age-related macular degeneration: A nationwide population-based cohort study.

Lee H, Han KD, Shin J.

Diabetes Metab. 2023 Mar 16;49(3):101442. doi: 10.1016/j.diabet.2023.101442. Online ahead of print.

QUANTIFIED ANASTOMOTIC AREAS OF NEOVASCULARIZATION AS FACTORS ASSOCIATED WITH FREQUENT RECURRENCE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

Lee H, Kim S, Kim MA, Chung H, Kim HC.

Retina. 2023 May 1;43(5):747-754. doi: 10.1097/IAE.0000000000003703.

PMID: 36729565

2022 (LAB year 1)

Accelerated aging phenotypes in the retinal pigment epithelium of Zmpste24-deficient mice.

Chae JB, Park CW, Lee HM, Choi LS, Park C, Kim J, Shin J, Hyeon J, Lee J, Lee H, Park HS, Nam CH, Chung H.

Biochem Biophys Res Commun. 2022 Dec 3;632:62-68. doi: 10.1016/j.bbrc.2022.09.061. Epub 2022 Sep 25.

Single-cell transcriptome of the mouse retinal pigment epithelium in response to a low-dose of doxorubicin.

Lee H, Lee HY, Chae JB, Park CW, Kim C, Ryu JH, Jang J, Kim N, Chung H.

Commun Biol. 2022 Jul 20;5(1):722. doi: 10.1038/s42003-022-03676-3.

Morphology of en face Haller vessel and macular neovascularization at baseline and 3 months as predictive factors in age-related macular degeneration.

Lee H, Kim S, Kim MA, Chung H, Kim HC.

Sci Rep. 2022 Jun 25;12(1):10821. doi: 10.1038/s41598-022-15139-0.

Effect of Intracameral Epinephrine and Indocyanine Green Use on Corneal Endothelium during Cataract Surgery

Myung Ae Kim, Youn Hye Jo, Hyungwoo Lee, Ki Cheul Shin

J Korean Ophthalmol Soc. 2022;63(2):142-149. 

• Pre LAB Period

2021 

Targeting senescent retinal pigment epithelial cells facilitates retinal regeneration in mouse models of age-related macular degeneration.

Chae JB, Jang H, Son C, Park CW, Choi H, Jin S, Lee HY, Lee H, Ryu JH, Kim N, Kim C, Chung H.

Geroscience. 2021 Dec;43(6):2809-2833. doi: 10.1007/s11357-021-00457-4. 

AUTOMATED QUANTIFICATION OF VITREOUS HYPERREFLECTIVE FOCI AND VITREOUS HAZE USING OPTICAL COHERENCE TOMOGRAPHY IN PATIENTS WITH UVEITIS.

Lee H, Kim S, Chung H, Kim HC.

Retina. 2021 Nov 1;41(11):2342-2350. doi: 10.1097/IAE.0000000000003190.

Choroidal Neovascularization and Haller Vessel Morphology Associated with Vision and Treatment Number after 1 Year in Age-related Macular Degeneration.

Kim S, Lee H, Chung H, Kim HC.

Korean J Ophthalmol. 2021 Oct;35(5):397-409. doi: 10.3341/kjo.2021.0085. 

Integrative analysis of the choroid by quantifying Haller vessel and choriocapillaris parameters in different drusen subtypes.

Lee H, Kim S, Kim MA, Jo YJ, Lee WH, Kim HC, Chung H.

Sci Rep. 2021 Jul 30;11(1):15509. doi: 10.1038/s41598-021-94627-1.

POST-TREATMENT PREDICTION OF OPTICAL COHERENCE TOMOGRAPHY USING A CONDITIONAL GENERATIVE ADVERSARIAL NETWORK IN AGE-RELATED MACULAR DEGENERATION.

Lee H, Kim S, Kim MA, Chung H, Kim HC.

Retina. 2021 Mar 1;41(3):572-580. doi: 10.1097/IAE.0000000000002898.

2020

Association between Exposure to Ambient Air Pollution and Age-Related Cataract: A Nationwide Population-Based Retrospective Cohort Study.

Shin J, Lee H, Kim H.

Int J Environ Res Public Health. 2020 Dec 10;17(24):9231. doi: 10.3390/ijerph17249231.

Characterization of microvascular tortuosity in retinal vein occlusion utilizing optical coherence tomography angiography.

Lee H, Kim MA, Kim HC, Chung H.

Sci Rep. 2020 Oct 20;10(1):17788. doi: 10.1038/s41598-020-74871-7.

Diabetic macular edema with pachychoroid features.

Kang K, Lee H, Jang M, Kim HC, Chung H.

BMC Ophthalmol. 2020 Oct 2;20(1):392. doi: 10.1186/s12886-020-01663-y.

ASSOCIATION OF TREATMENT RESPONSE WITH QUANTITATIVE CHANGES IN CHOROIDAL NEOVASCULARIZATION AND CHOROIDAL VESSEL IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

Lee H, Lee M, Kim MA, Chung H, Kim HC.

Retina. 2020 Sep;40(9):1704-1718. doi: 10.1097/IAE.0000000000002678.

Two-dimensional Quantitative Effects of Anti-vascular Endothelial Growth Factor and Dexamethasone Implants on Retinal Vein Occlusion.

Jang M, Lee H, Kim HC, Chung H.

J Korean Ophthalmol Soc. 2020;61(11):1279-1287.   Published online November 15, 2020  

2019

Association of imaging factors derived from convolutional neural network with visual outcomes in age-related macular degeneration and polypoidal choroidal vasculopathy.

Lee H, Jang M, Kim HC, Chung H.

Sci Rep. 2019 Dec 27;9(1):19857. doi: 10.1038/s41598-019-56420-z.

Three-dimensional analysis of morphologic changes and visual outcomes in diabetic macular edema.

Lee H, Kang KE, Chung H, Kim HC.

Jpn J Ophthalmol. 2019 May;63(3):234-242. doi: 10.1007/s10384-019-00657-8. 

2018

Changes in Stromal and Luminal Areas of the Choroid in Pachychoroid Diseases: Insights Into the Pathophysiology of Pachychoroid Diseases.

Lee M, Lee H, Kim HC, Chung H.

Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):4896-4908. doi: 10.1167/iovs.18-25018.

Automated Segmentation of Lesions Including Subretinal Hyperreflective Material in Neovascular Age-related Macular Degeneration.

Lee H, Kang KE, Chung H, Kim HC.

Am J Ophthalmol. 2018 Jul;191:64-75. doi: 10.1016/j.ajo.2018.04.007. 

QUANTIFICATION OF RETINAL VESSEL TORTUOSITY IN DIABETIC RETINOPATHY USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Lee H, Lee M, Chung H, Kim HC.

Retina. 2018 May;38(5):976-985. doi: 10.1097/IAE.0000000000001618.

• Selected for BRIC highly cited journal (>120 citations).

Prognostic Factors for Functional and Anatomic Outcomes in Patients with Diabetic Macular Edema Treated with Dexamethasone Implant.

Lee H, Kang KE, Chung H, Kim HC.

Korean J Ophthalmol. 2018 Apr;32(2):116-125. doi: 10.3341/kjo.2017.0041. 

Association Between Soluble CD14 in the Aqueous Humor and Hyperreflective Foci on Optical Coherence Tomography in Patients With Diabetic Macular Edema.

Lee H, Jang H, Choi YA, Kim HC, Chung H.

Invest Ophthalmol Vis Sci. 2018 Feb 1;59(2):715-721. doi: 10.1167/iovs.17-23042.

2017

Three-Dimensional Analysis of Morphologic Changes and Visual Outcomes in Neovascular Age-Related Macular Degeneration.

Lee H, Jo A, Kim HC.

Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1337-1345. doi: 10.1167/iovs.16-20637.

24-hour Ambulatory Blood Pressure in Normal Tension Glaucoma: Associations with Retinal Vessel Diameter and Visual Field Defect Progression 

Jo A, Lee H, Cho BJ.

J Korean Ophthalmol Soc 2017;58(11):1242-1247 

2016

BASELINE SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHIC HYPERREFLECTIVE FOCI AS A PREDICTOR OF VISUAL OUTCOME AND RECURRENCE FOR CENTRAL SEROUS CHORIORETINOPATHY.

Lee H, Lee J, Chung H, Kim HC.

Retina. 2016 Jul;36(7):1372-80. doi: 10.1097/IAE.0000000000000929.

CORRELATION BETWEEN OPTICAL COHERENCE TOMOGRAPHIC HYPERREFLECTIVE FOCI AND VISUAL OUTCOMES AFTER ANTI-VEGF TREATMENT IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION AND POLYPOIDAL CHOROIDAL VASCULOPATHY.

Lee H, Ji B, Chung H, Kim HC.

Retina. 2016 Mar;36(3):465-75. doi: 10.1097/IAE.0000000000000645.

~2015

Long-term effect of latanoprost on central corneal thickness in normal-tension glaucoma: five-year follow-up results.

Lee H, Cho BJ.

J Ocul Pharmacol Ther. 2015 Apr;31(3):152-5. doi: 10.1089/jop.2014.0109.

Correlation between optical coherence tomographic hyperreflective foci and visual outcomes after intravitreal bevacizumab for macular edema in branch retinal vein occlusion.

Kang JW, Lee H, Chung H, Kim HC.

Graefes Arch Clin Exp Ophthalmol. 2014 Sep;252(9):1413-21. doi: 10.1007/s00417-014-2595-5. 

Increased 26S proteasome non-ATPase regulatory subunit 1 in the aqueous humor of patients with age-related macular degeneration.

Lee H, Choi AJ, Kang GY, Park HS, Kim HC, Lim HJ, Chung H.

BMB Rep. 2014 May;47(5):292-7. doi: 10.5483/bmbrep.2014.47.5.193.

Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1.

Choi SJ, Chung SS, Rho EJ, Lee HW, Lee MH, Choi HS, Seol JH, Baek SH, Bang OS, Chung CH.

J Biol Chem. 2006 Oct 13;281(41):30669-77. doi: 10.1074/jbc.M604033200.