On going Research

1. Prevalence of carbapenem-resistant Gram-negative bacteria among the clinical isolates collected from Tamil Nadu, India.

2. Studies on antibiotic resistance vs tolerance vs persistence: isolation of persister cells from Pseudomonas aeruginosa to study their evolution.

3. Molecular characterization of hypervirulent colistin-resistant Klebsiella species and screening its putative virulence genes.

4. Mechanism of tigecycline-resistance through dormant cells.

5. Isolation of lytic phages for the treatment of MRSA infections and also to study their sublineage that results in heteroresistance resistome profile.

6. Identifying lytic phages as a therapeutic agent for aquaculture pathogenesis: Vibrio infection in shrimp and fish.

7. Molecular cloning and expression of endolysin gene targeting Vibrio species and application.

8. CRISPR-Cas technology: Mycobacterium smegmatis.

9. Isolation and characterization of bacteriophages infecting Acinetobacter baumannii and Pseudomonas aeruginosa.

10. Synergistic effect of bacteriophages and antibiotics: appearance of bacteriophage insensitive mutants (BIMs) and combination therapy.

11. Eradication of E. coli and K. pneumoniae biofilms using phage cocktails.