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This google site you are visiting mainly describes my previous research as a graduate student and a postdoc.

I worked with James Ferrell at Stanford University with a postdoc fellowship from the Damon Runyon Cancer Research Foundation. I obtained my PhD in the physics department at MIT, where I worked with Alexander van Oudenaarden, doing biophysics and systems biology. My research interests focus on understanding the dynamics of stochastic gene expression and signal transduction in single cells,  with an integration of experiment and theory. Please check my Research and Methods & Software web pages for more information.

Publication

5.     Q. Yang and J. E. Ferrell Jr.. The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch. Nat Cell Biol 15, 519 (2013).

4.      J. E. Ferrell Jr., T. Tsai, and Q. Yang. Modeling the Cell Cycle: Why Do Certain Circuits Oscillate? Cell 144, 874 (2011).

3.      Q. Yang*, B. F. Pando*, G. Dong, S. S. Golden, and A. van Oudenaarden. Circadian gating of the cell cycle revealed in single cyanobacterial cells. Science 327, 1522 (2010). Spotlighted in MIT News.

2.      G. Dong, Q. Yang, Q. Wang, Y. Kim, T. L. Wood, K. W. Osteryoung, A. van Oudenaarden, and S. S. Golden. Elevated ATPase activity of KaiC applies a circadian checkpoint on cell division in Synechococcus elongatus. Cell 140, 529 (2010). Featured in Cell Previews.

1.      B. B. Kaufmann*, Q. Yang*, J. T. Mettetal, and A. van Oudenaarden. Heritable stochastic switching revealed by single-cell genealogy. PLoS Biol 5, e239 (2007).

      * Equal contribution.