The 2024 Lab Learning Program and Summer Interns cohort and another fantastic summer!
Meet the group (left to right in group photo): James Jun (intern), Rala Abu Sulami (intern), Riya Jain (LLP), Rachel Kim (LLP), Kai Vanderhoof (LLP), Abir Modak (LLP), and Ayush Tripathi (LLP)
Congrats to the 2023 Lab Learning Program cohort for a great summer. Best for the research to come :)
Meet the group:
Shreyas Garimella, Elizabeth (Libby) Dai, Supraj Gunda, Chloe Velez, Sohum Trivedi, and Steven Amanat
Research
Burst Analysis Spectroscopy is a fluorescence technique developed in my lab to explore and resolve complex populations of macromolecules in free-solution including viruses and protein aggregates. Together with my collaborators at TAMU (Hays Rye), BAS has been used to investigate a variety of dynamic, non-equilibrium processes that are at the core of a wide range of biological processes (e.g. protein aggregation and dis-aggregation; vesicle assembly and disassembly; phage DNA loading). We have recently expanded the method to include multi-color particles (mcBAS).
Structured Light Scanning is also an active project where tumor growth can be tracked and characterized in more detail than ever before.
Microfluidics devices and techniques are widely applicable in both biochemistry and biophysics. My lab space includes a soft-materials lab shared with Bob Austin and accessible to the larger university community upon request.
Magnetic nanoparticles can be incredibly versatile components in directed self-assembling scaffolds and soft-robotics. Recently, students in my lab have done a range of projects from axon-guidance to novel magnetically controlled microbots.
Recognizing specific structures in complex, dynamics populations remains challenging even using modern techniques. We are exploring the use of Deep & Machine Learning techniques and simulation (e.g. Monte Carlo and Agent Based Modeling) to explore unsupervised classification and collective behavior.
Machine Learning projects (coming soon)
Zebrafish CNN
Burst analysis
Teaching , Outreach & Advising
Introductory physics can be subtle and beautiful ... and fun to learn. Information about some of the classes I have taught and developed in the past 10 years can be found here. I am especially interested in new methods in Introductory Physics for the Life Sciences (IPLS). Each summer I host several high school and early stage undergraduate students as well.
My lab is very active in high school outreach as well as undergraduate advising and research. Some of the programs I am actively involved in include:
Princeton's Laboratory Learning Program (LLP)
The molecular biophysics NSF summer REU program
Academic advisor for Butler College
Junior & Senior thesis advising
Department and lab documents, schedules, etc
About me: I am a biophysicist and faculty lecturer in the department of physics at Princeton University. My research focuses on using cross-disciplinary techniques to study a range of questions in the life sciences. My lab is also very active in research outreach and development of methods for non-traditional instruction of introductory physics.
CONTACT:
puchalla at princeton.edu
Set up a time to talk: https://calendly.com/puchalla/general-meeting