Publications

• Sadananda, D., Mallikarjunaswamy, A.M.M., Prashantha, C.N. et al. Recent development in chemosensor probes for the detection and imaging of zinc ions: a systematic review. Chem. Pap. (2022). https://doi.org/10.1007/s11696-022-02284-z

• Majji Rambabu, KR Dasegowda, CN Prasantha, Karthick Vasudevan, (2022). Structure based drug design of Influenza virus double mutant strains to identify potential neuraminidase inhibitors: A computational approach. Dickensian Journal, Vol 22, Issue 6, 1779-1793.

• Kiran Kumar Burranboina, K.M. Kumar, G.B. Manjunatha Reddy, R. Yogisharadhya, C.N. Prashantha, Awalagaway Dhulappa, (2022) GC-MS analysis, molecular Docking and pharmacokinetic studies of various bioactive compounds from methanolic leaf extracts of Leucas aspera (L) against anti - Capripox viral activity. Chemical Data Collections,Volume 39, 2022, 100873, ISSN 2405-8300,

• Lakshminarayana, L., Veeraraghavan, V., Gouthami, K. et al. Effect of Abutilon indicum (L) Extract on Adipogenesis, Lipolysis and Cholesterol Esterase in 3T3-L1 Adipocyte Cell Lines. Ind J Clin Biochem (2022). https://doi.org/10.1007/s12291-022-01022-2.

• Kuruvalli Gouthami, V Veeraraghavan, L Lavanya, C.N. Prashantha (2022). Molecular docking studies for Vitex negundo (L) leaf extract compounds against Wnt- signaling proteins towards the treatment of colon cancer. Chemical Data Collections, Volume 38, April 2022, 100829.

• Gouthami, K., Veeraraghavan, V. & Nagaraja, P. In-silico characterization of phytochemicals identified from Vitex negundo (L) extract as potential therapy for Wnt-signaling proteins. Egypt J Med Hum Genet 23, 3 (2022). https://doi.org/10.1186/s43042-022-00219-7.

• Lavanya L, Veeraraghavan V, Renuka S, Prashantha CN. Study of in vitro activity on glucose uptake of 3T3L-1 cells, RIN5f cells, and glycemic index stimulation inhibitory effect of Abutilon indicum (L.) extract. J Appl Biol Biotech. 2022;10(01):145-156.

• B. Kulkarni, K. Manjunatha, Muthipeedika Nibin Joy, Ayyiliath Meleveetil Sajith, C. N. Prashantha, Ranjith Pakkath & Mohammed B. Alshammari. Design, synthesis, and molecular docking studies of some 1-(5-(2-fluoro-5-(trifluoromethoxy) phenyl)-1,2,4-oxadiazol-3-yl) piperazine derivatives as potential anti-inflammatory agents. Mol Divers (2021).

• Damodaran, B., Prabhu, B., Vinoth Kumar, G., Prashantha, C. N., Pulakuntla, S. R., Sankolli, G. M., & Venkataraman, P. (2021). RNA Sequencing-based Transcriptomic profiles of HeLa, MCF-7 and A549 cancer cell lines treated with Calotropis gigantea leaf extracts. Gene Reports, 23, 101119.

• Prashantha, C. N., Gouthami, K., Lavanya, L., Bhavanam, S., Jakhar, A., Shakthiraju, R. G., Suraj, V., Sahana, K. V., Sujana, H. S., Guruprasad, N. M., & Ramachandra, R. (2021). Molecular screening of antimalarial, antiviral, anti-inflammatory and HIV protease inhibitors against spike glycoprotein of coronavirus. Journal of molecular graphics & modelling, 102, 107769.

• Nisha Rajasekhar, Ramesh N, Prashantha C.N. Identification, and In-silico Prediction of Hermetia illucens Larval Protein that Inhibits the Progression of Cervical Cancer. International Journal of Engineering and Advanced Technology (IJEAT), ISSN: 2249 – 8958, Volume-9 Issue-3, February 2020.

• Prashantha CN, Adhikesavan Hari Krishnan, V Veena, Lakshmi B, Shanmugavalli R, Sonia Theres Gubert, Tanya Shah, Oshin K, Togam Ringu & Sisir Nandi (2020). Atranorin, an antimicrobial metabolite from lichen Parmotrema rampoddense exhibited in vitro anti-breast cancer activity through interaction with Akt activity. Journal of Biomolecular Structure and Dynamics. Page 1-19.

• Prashantha C.N, Nisha Rajasekhar, Ramesh. N. Isolation and Characterization of Hermetia Illucens Larval Protein for the Assessment of Inhibitory Activity against MCF7 and HeLa cell Lines. International Journal of Innovative Technology and Exploring Engineering (IJITEE). 2020. Volume 9, Issue 3, Pages 3045-3050.

• B. Kiran Kumar, K. M. Kumar, G. B. Manjunatha Reddy, Sunil Abraham, R. Yogisharadhya, C. N. Prashantha. Molecular Modeling and Insilico Engineering of PapMV-CP towards Display and Development of Capripox Viral like Particles Based on Immunogenic P32 Envelop Protein is the Homologous of the Vaccinia-Viral H3L Gene: An Insilico Approach. International Journal of Peptide Research and Therapeutics, 2020, pp 1-13.

• Ahmad Zonoubi, Prashantha CN, D Visaga Perunal, Zahra Mafibaniasadi. In Silico Analysis Of Active Constituents Of Silymarin As Alpha-Glucosidase Enzyme Inhibitors In Type 2 Diabetes Mellitus. Asian Journal of Pharmaceutical and Clinical Research. 2019 12(9), 225-229.

• Damodaran B, Nagaraja P, Jain V, Manuja Viraj Wimalasiri M P, Sankolli G M, Kumar G V, Prabhu V. Phytochemical screening and evaluation of cytotoxic activity of Calotropis gigantea leaf extract on MCF7, HeLa, and A549 cancer cell lines. J Nat Sc Biol Med 2019; 10:131-8.

• Prashantha C, N. Transcriptome analysis to identify disease resistance genes through novel next generation sequencing applications for the predictive medicine. Journal of Applied Bioinformatics & Computational Biology. 2019 (8).

• Dhanya V. Menon, *Darshan Patel, Prashanth Nagaraja, Chaitanya G. Joshi. The Case of Efficient Animal Models for Regenerative Medicine: A Computational Investigation. Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences. 2019. 5(2), 282-294.

• Rajaganapathy Kaliyaperumal, Manjunatha Panduranga Mudugal, Prashantha Nagaraja, Nageena Taj. Exploration of Novel Sulpho Tyrosine Based Unnatural Amino Acid Ligand for Inhibition of Human Shp2; A Computational Approach. Journal of Drug Design and Medicinal Chemistry. Vol. 4, No. 3, 2018, pp. 22-34.

• Navaneethakrishnan Polachi, Boopathi Subramaniyan, Prashantha Nagaraja, Kannan Rangiah, Mathan Ganeshan. Extract from Butea monosperma inhibits β-catenin/Tcf signaling in SW480 human colon cancer cells. Gene Reports. 2018, 10, 79-89.

• Sukanya, V.K., Nagaraja, P., Manokaran, S., Hanumanthareddy, A. Reddy, M. and Surana, P. (2018) Microarray Meta-Analysis of BRCA1 Mutated Genes Involved in Breast Cancer. Open Access Library Journal, 5: e5000.

• C.N.Prashantha, Maheswari L Patil, Shivakumar B Madagi. Whole Exome Sequence Analysis to Predict Functional Biomarkers for Pancreatic Cancer. International Journal of Advanced Research in Computer Science, 2018, 9(3), 361-367.

• C.N.Prashantha, Maheswari L Patil, Shivakumar B Madagi. Enabling rapid and efficient selection of Next generation sequencing algorithms to align sequences to predict differentially expressed genes in cancer. Canadian Journal of Biotechnology, 2017, 1, 22.

• Reshma Jacob, Seema J Patel, Prashantha C N. Transcriptome Analysis of m-RNA Expression Profiling To Predict Potential Biomarkers Induced In Breast Cancer-BRCA1. Asian Journal of Pharmaceutical and Clinical Research, 2016, Vol. 9, no. 6, pp. 270-3.

• Kaviyarasi, N.S. and Prashatha, C.N. and Suryanarayana, V.V.S. In silico analysis of inhibitor and substrate binding site of serrapeptidase from serratia marcescens MTCC 8708. International Journal of Pharmacy and Pharmaceutical Sciences, 2016, 8 (4). pp. 123-128.

• Pooja S., Muttagi A.P., Patel S.J., Gurumurthy H., and Prashantha C.N., Whole transcriptome cerebral cortex gene analysis in Alzheimer’s diseases, Computational Molecular Biology, 2016, 6(2): 1-9.

• Shashank K.S., Mamatha H.R., and Prashantha C.N., Meta-Analysis of Gene Expression Data of Multiple Cancer Types To Predict Biomarkers and Drug Targets Interactions in Ovarian Cancer, Computational Molecular Biology, 2015, 5(5): 1-9.

• Divya, V., Anitha P. Muttagi, Seema J Patel, Gurumurthy, H. and Prashantha Nagaraja. Gene Expression Profile of Ovarian Cancer Dataset that helps to Predict Potential Biomarkers. International Journal of Current Research in Life Sciences. 2015, Vol.4, No.08, pp.321-327.

• Anuradha, Shilpa N, Shambu M G, Anitha P.M, Tanusree Bhattacharya, Prashantha Nagaraja, Molecular Characterization of Salmonella SP1 Component Proteins Involved in Pathogenicity and is Used for Potential Drug Targets.American journal of Pharmacy and Health Research, 2015, 3(4).

• P.S. Pradeep, T.O. Shrungesh Kumar, C.N. Prashantha, K.M. Mahadevan. Synthesis and Molecular Docking study of 2-Aryl/Heteroaryl quinoline - 4-Carboxylic Acids for Antimalarial, Antituberculosos and Anticancer Activities. International Journal of Chemical and Physical Sciences, 2015, 4(4), 74-92.

• P.S. Pradeep, T.O. Shrungesh Kumar, C.N. Prashantha, K.M. Mahadevan. Synthesis, in-vitro Antibacterial Toxicity and Molecular Docking Anticancer Activity of Novel N-[(2-Chloroquinolin-3-yl) methylidene]-2-aniline Schiff bases. International Journal of Current Pharmaceutical Research, 2015, Vol 7, Issue 3, 37-46.

• Navaneethakrishnan Polachi, Prashantha Nagaraja, Boopathi Subramaniyan, Ganeshan Mathan. Antiproliferative Activity of N-Butanol Floral Extract from Butea Monosperma against HCT 116 Colon Cancer Cells; Drug Likeness Properties and In Silico Evaluation of Their Active Compounds toward Glycogen Synthase Kinase-3β/Axin and β -Catenin/T-Cell Factor-4 Protein Complex. Asian Journal of Pharmacy and Clinical Research, 2015, Vol 8, Issue 1, 134-141.

• Jagadeesh N. M, K.M. Mahadevan, H Jayadevappa, H. N Harishkumar, Rajesha G, Prashantha Nagaraja. Synthesis and in vitro cytotoxicity study of 3-(1H-indol-3-yl)-1, 3-diphenylpropan-1-ones. Medicinal Chemistry Research, 2014, Vol 23, Iss 6, pp 2880–2889.

• Pradeep P S, Kiran Kumar, H Chandrashekarappa, Jagadeesh N M, Prashantha Nagaraja, K M Mahadevan. Toxicity and Molecular Docking Studies of Tetrahydroquinoline against Microbial, Cancer, Retinoic Acid Receptor, Inflammatory, Cholesterol Ester Transferases and Parasitic Protein Receptors. International Journal of Pharmacy and Pharmaceutical Sciences, 2014, Vol 7, Issue 2, 448-459.

• NM Jagadeesh, KM Mahadevan, MN Kumara, C N Prashantha. Synthesis and molecular docking study of N-alkyl/aryl-2-aryl indol-3-yl glyoxylamides as novel anticancer agents. International Journal of Pharmacy and Pharmaceutical Science, 2014, Volume 6, Issue 2, Pages 921-926.

• Navaneethakrishnan P, Prashantha C N, Boopathi S, Sabitha R, Mathan G. (2013) In Silico Design of Butea monosperma Floral Derived Compounds and Its Inhibitory Effect on β-Catenin, GSK-3β and APC Complex Proteins in Colorectal Cancer. International Journal of Drug Discovery, 2013, Volume 5, Issue 1, pp.-191-197.

• CN Prashantha, Arti Patil, Shanmuga Priya. Designing of Anti Dengue Drug Molecule against Insilico Modeled Target DC-Sign (CD-209). International Journal of Advanced Computer Research, 2013, 3(3), 215-223.

• Prashantha Nagaraja, Kavya Parashivamurthy, Nandini Sidnal, Siddappa Mali, Dakshyani Nagaraja, and Sivarami Reddy. Analysis of gene expression on ngn3 gene signaling pathway in endocrine pancreatic cancer. Bioinformation, 2013, 9(14), 739–747.

• R Priscilla, Prashantha CN, S Swamynathan, Analysis of Gene expression data using MATLAB Software.International Journal of Artificial Intelligence and Computational Research 2010, 1(1), 51-56.

Conference Publications

• Prashantha Nagaraja, Arighni Guhathakurta, Shweta Sukla Baidya and Pujitha Krishnasamudram. Virtual Screening of Bio-active Compounds as an Inhibitor of c-FLIP Protein for Cancer Treatment. Conference on Drug Design and Discovery Technologies, 2019, p21-24 Royal Society of Chemistry.

• Prashantha Nagaraja, Sonika Rai, Alivia Saha, Ragini V Murthy, Ramachandra R. Differentially expressed neurogenin-3 gene in neuronal cell development of pancreatic cell. National Conference on Computational World in Life Sciences, Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences, 2019, 5(2), 282-294.

• Kiran Raj T Akash Dnyanoba Adude, Rahul Dnyanoda Chandawar, Gajanan Balaji Gaikwad, Prashantha Nagaraja. The identification and validation of differentially expressed genes of both mouth buccal cavity and nasal cavity epithelial tissues of lung cancer. National Conference on Computational World in Life Sciences, Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences, 2019, 5(2), 208-218.

• R. Ramachandra Swetha Sukla, Padmaja, Arighni, Prashantha C N, Guruprasad NM. Computational approaches and molecular docking of target natural chemicals for target as glutathione-stransferase. National Conference on Computational World in Life Sciences, Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences, 2019, 5(2), 200-207.

• Nisha Rajasekhar, Asiya Rozinder, D.B.M. Virupakshaiah, Prashantha C.N. Peptidomimetics: structural and pharmacological identification of novel peptide of target chymase enzyme activity to predict asthma treatment. National Conference on Computational World in Life Sciences, Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences, 2019, 5(2), 185-199.

• Prashantha C.N, Gouthami K, Veeraraghavan V, Vani Puttaraju, Ramachandra R. Pharmacogenomics approach as personalized medicine for type 2 diabetes mellitus. National Conference on Computational World in Life Sciences, Research Journal of Life Sciences, Bioinformatics, Pharmaceutical and Chemical Sciences, 2019, 5(2), 19-37.