Publications

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PUBLICATIONS

1. Bhalode, P, Najmi, S., and Vlachos, D. (2024) "Computation-Guided Removal of 6PPD from End-of-Life Waste Tires." ACS Sustainable Resource Management . 1 (10), 2276-2283.

2. Najmi, S., Bhalode, P., Baker-Fales, M., Vance, B.C., Selvam, E., Yu, K., Zheng, W. and Vlachos, D.G., 2024. End-of-life tire decontamination from 6PPD and upcycling. Nature Chemical Engineering, pp.1-11.

3. Andini, E., Bhalode, P., Gantert, E., Sadula, S. and Vlachos, D.G., (2024) Chemical recycling of mixed textile waste. Science Advances, 10(27), p.eado6827.

4. Bhalode, P., Razavi, S.M., Tian, H., Roman-Ospino, A., Scicolone, J., Callegari, G., Dubey, A., Koolivand, A., Krull, S., O'Connor, T. and Muzzio, F.J., 2024. Statistical data treatment for residence time distribution studies in pharmaceutical manufacturing. International Journal of Pharmaceutics, 657, p.124133.

5. Bhalode, P., Razavi, S. M., Roman-Ospino, A., Scicolone, J., Callegari, G., Tian, G., Koolivand, A., Krull, S., Ierapetritou, M. G., and Muzzio, F. J. (2023) Optimal quantification of residence time distribution profiles from a quality assurance perspective. International Journal of Pharmaceutics 122653. 

6. Bhalode, P., Tian, H., Gupta, S., Razavi S. M., Roman-Ospino, A., Talebian S., Singh R., Scicolone J., Muzzio F. J., & Ierapetritou, M. (2021) Using Residence time distribution in pharmaceutical solid dose manufacturing – a critical review. International Journal of Pharmaceutics 121248.

7. Bhalode, P. & Ierapetritou, M. (2021) Hybrid multi-zonal compartment modeling for continuous powder blending processes. International Journal of Pharmaceutics 602, 120643.

8. Bhalode, P. & Ierapetritou, M. (2020) A review of existing mixing indices in solid-based continuous blending operations. Powder Technology 373, 195–209.

9. Bhalode, P. & Ierapetritou, M. (2020) Discrete element modeling for continuous powder feeding operation: Calibration and system analysis. International Journal of Pharmaceutics 585, 119427.

10. Chen Y., Kotamarthy L., Dan A., Sampat C., Bhalode P., Singh R., Glasser B. J., Ramachandran R., & Ierapetritou M. G. (2023) Optimization of key energy and performance metrics for drug product manufacturing. International Journal of Pharmaceutics. 631, 122487.

11. Razavi, S.M., Román-Ospino, A.D., Bhalode, P., Scicolone, J., Callegari, G., Dubey, A., Koolivand, A., Krull, S., Tian, G., Xu, X. and O'Connor, T., (2023). Selection of an appropriate tracer to measure the residence time distribution (RTD) of continuous powder blending operations. Powder Technology, 429, 118864.

12. Baker-Fales, M., Chen, T.-Y., Bhalode, P., Wang, Z. & Vlachos, D. G. (2023). Microwave enhancement of extractions and reactions in Liquid-Liquid biphasic systems. Chemical Engineering Journal, 146552.

13. Tian, H., Bhalode, P., Razavi, S. M., Koolivand, A., Muzzio, F. J., & Ierapetritou, M. G. (2022) Characterization and Propagation of RTD Uncertainty for Continuous Powder Blending Processes. International Journal of Pharmaceutics, 122326.

14. Sampat, C., Kotamarthy, L., Bhalode, P., Chen, Y., Dan, A., Parvani, S., Dholakia Z, Singh R, Glasser BJ, Ierapetritou M, & Ramachandran, R. (2022). Enabling energy‐efficient manufacturing of pharmaceutical solid oral dosage forms via integrated techno‐economic analysis and advanced process modeling. Journal of Advanced Manufacturing and Processing, 4(4), e10136.

15. Chen, Y., Yang, O., Sampat, C., Bhalode, P., Ramachandran, R., & Ierapetritou, M. (2020). Digital twins in pharmaceutical and biopharmaceutical manufacturing: a literature review. Processes, 8(9), 1088.

MANUSCRIPTS IN PREPARATION (available on request)

1.     Bhalode, P., Najmi, S., Vlachos, D., (2023). Computation-driven methodology for solvent-based removal of harmful additive 6PPD from waste tires.

2.     Bhalode, P., Razavi, S. M., Roman-Ospino, A., Scicolone, J., Callegari G., Dubey, A., Koolivand, A., Krull, S., O’Connor, T., Muzzio, F. J., Ierapetritou, M. G., (2023). Statistical data pre-treatment for residence time distribution studies in pharmaceutical manufacturing.

3.     Najmi, S., Bhalode, P., Vlachos, D., (2023). Microwave assisted extraction of additive from waste tires and upcycling.

BOOK CHAPTER

1.     Chen, Y., Ierapetritou, M. and Bhalode, P., 2023. Process Systems Engineering Tools toward Digital Twins of Pharmaceutical Continuous Manufacturing Processes. In Continuous Pharmaceutical Processing and Process Analytical Technology (pp. 449-475). CRC Press.