Volume of distribution = 123 L (78.1%)

Within 2.5 hours of administration, the drug is distributed to gastrointestinal tract, liver, lungs, kidneys, heart wall, bone marrow, and salivary glands.

60% to 70% bound to human plasma proteins

Elimination half-life = 41.6 hours (68.8%)

Clearance (CL) = 2.04 L/h (31.5%)

Excretion = primarily eliminated renally