There are three domains of life on Earth: Bacteria, Archaea, and Eukaryotes
An evolutionary algorithmic phase transition 2.6 billion years ago may have sparked the emergence of eukaryotic cells (Phys.org 17Apr2025)
└Muro et al. (2025) The emergence of eukaryotes as an evolutionary algorithmic phase transition
Origin of life: How a special group of single-celled organisms laid the foundation for complex cells (Phys.org 21Mar2025)
└Wollweber et al. (2025) Microtubules in Asgard archaea
A Test for Life Versus Non-Life (NY Times 31Jul2024)
Ancient microbes offer clues to how complex life evolved (Phys.org 16Jul2024)
How did multicellularity evolve? (Niklas, 2014)
Microbes in Central Park Soil are very diverse (Ramirez et al., 2014)
Virus origins suggest they are alive (Nasir & Caetano-Anollés, 2015)
Organisms without an organized nucleus or organelles, e.g. Bacteria & Archaea
Dominant form of life on earth
Heterotrophic and autotrophic forms
Aerobic (O2-rich) and anaerobic (O2-free) environments
The oldest living organisms on Earth (at least 3.5 billion year old)
There are two (2) distint groups of prokaryotes on Earth: Bacteria and Archaea
Prokaryotic, unicellular & colonial
Possess DNA, but not membrane-bound organelles
Prokaryotic, unicellular
Possess DNA, but not membrane-bound organelles
Possess enzymes and transcription factors more similar to eukaryotes
n.b. Some evidence supporting the endiosymbiotic theory indicates that origin of eukaryotes came about through an archaean host, which engulfed a bacterium. This bacterium became the first organelle, such as the mitochondria
Paleoarchean (maybe Eoarchean or late Hadean) - present
Above: Categories of life; this is an organizational image, not an evolutionary tree
Below: A cladogram of the domains of life
Organisms possess organelles such as a nucleus
e.g. "protists", plants, fungi, and animals
Eukaryotes probably evolved around 2.0 billion years ago (Paleoproterozoic)
Both microscopic and macroscopic forms exist on Earth
Autotrophs (e.g. plants and photosynthetic algae) & heterotrophs (e.g. fungi / animals)
Eukaryotes are dependent on an aerobic (oxygen-rich) environment
Four major groups of eukaryotes:
Archaeaplasta (Plants)
Unikonts (Fungi & Slimemolds)
Chromalveolates (Various algae groups)
Excavates (Various unicellular protists)
Paleoproterozoic - present
Above: Biomass of organisms on Earth as represented by the amount of carbon in each group
n.b. Plants account for 83% of all carbon found in Earth's organisms (Bar-on, Phillips, and Milo 2018)
Genetic entities that are in a "grey zone" between living and non-living states
A virus does not replicate or function independently, so by the biological definition, a virus cannot be categorized as a living organism.
From a genetic and evolutionary point of view, a living organism is defined by its ability to reproduce. From this view, a virus is alive since it can produce similar offspring.
Possess a single strand of genetic information inside a protein capsule
Require a host to reproduce
Lack most of the internal structure and machinery, such as biosynthetic processes
Viruses are not constructed as cells
Above: A representation of what the COVID-19 virus would look like
How do the three domains differ and how are they similar?
What are examples of each domain?
What is multicellularity? What is colonial?
What makes a virus living or non-living