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"New, Natural, and Progressive Finding"
For the future!
Jeong Hee Hong
Jeong Hee Hong
Professor, Ph.D.
Department of Physiology,
Professor, Ph.D.
Department of Physiology,
College of Medicine, Gachon University
College of Medicine, Gachon University
[Address] Lee Gil Ya Cancer and Diabetes Institute.
155 Gaetbeolro, Yeonsu-gu, Incheon, Korea 21999
[Office] +82-32-899-6682
[E-mail] minicleo@gachon.ac.kr
Publications
Publications
Lee Eun Sun, Hyeong Jae Kim, Dongun Lee, Jung Yun Kang, Dong Min Shin, and Jeong Hee Hong. Rheumatoid arthritis severity is mediated by a crosstalk between synoviocytes and mature osteoclasts through the calcium and cytokine feedback loop. Exp Mol Med. 2025 Feb 3. doi: 10.1038/s12276-025-01401-8. Online ahead of print.
Lee E, Yang D, Hong JH. Prominent Naturally Derived Oxidative-Stress-Targeting Drugs and Their Applications in Cancer Treatment. Antioxidants (Basel). 2025 Jan 3;14(1):49. doi: 10.3390/antiox14010049.
Kim HJ and Hong JH. Multiplicative effects of naturally derived essential oils and ac-tive components on skin tissue and skin cancers. International Journal of molecular sciences. 2024. May 15;25(10):5397. doi: 10.3390/ijms25105397.
Kim HJ and Hong JH. Trafficking of carbonic anhydrase 12 and bicarbonate transporters by histamine stimulation mediates intracellular acidic scenario in lung cancer cells. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2247181. doi: 10.1080/14756366.2023.2247181.
Lee DU, Shin DM, and Hong JH. Modulation of lysosomal Cl- mediates migration and apoptosis through the TRPML1 as a lysosomal Cl- sensor. Cells. 2023, 2023 Jul 12;12(14):1835. doi: 10.3390/cells12141835.
Kim HJ, Lee PCW, and Hong JH. Overview of cellular homeostasis-associated nuclear envelope lamins and associated input signals, Frontiers in cell and developmental biology. 2023 May 12;11:1173514. doi: 10.3389/fcell.2023.1173514.
Ji M, Son KH, Hong JH. Addition of oh8dG to cardioplegia attenuated myocardial oxidative injury through the inhibition of sodium bicarbonate cotransporter activity. Antioxidants (Basel). 2022 Aug 24;11(9):1641. doi: 10.3390/antiox11091641.
Lee DU, Lee PCW, Hong JH*, Shin DM*. Estrogen treatment reduced oxalate transporting activity and enhanced migration through the involvement of SLC26A6 in lung cancer cells. Toxicology in vitro, 2022 Apr 29, 82:105373. *Co-correspondence.
Kim HJ, Lee PCW, and Hong JH, Chloride Channels and Transporters: Roles beyond Classical Cellular Homeostatic pH or Ion Balance in Cancers. Cancers. 2022 Feb 9;14(4):856.
Ji M, Ryu HJ, Baek HM, Shin DM, Hong JH. Dynamic synovial fibroblasts are modulated by NBCn1 as a potential target for rheumatoid arthritis. Experimental & Molecular Medicine. 2022 Apr;54(4):503-517.
Ji M, Ryu HJ, Hong JH, Synovial Fluid of Patient With Rheumatoid Arthritis Enhanced Osmotic Sensitivity Through the Cytotoxic Edema Module in Synoviocytes. Frontiers in cell and developmental biology. 2021 Aug 31;9: 700879.
~~~ and others
~~~ and others
Ji M, In Lee S, Lee SA, Son KH, Hong JH.
Ji M, In Lee S, Lee SA, Son KH, Hong JH.
Enhanced activity by NKCC1 and Slc26a6 mediates acidic pH and Cl–movementaftercardioplegia-inducedarrestofdb/dbdiabeticheart.Mediators of Inflammation 2019 Sep 8;2019:7583760.
Enhanced activity by NKCC1 and Slc26a6 mediates acidic pH and Cl–movementaftercardioplegia-inducedarrestofdb/dbdiabeticheart.Mediators of Inflammation 2019 Sep 8;2019:7583760.
Hwang S, Shin DM, Hong JH.
Hwang S, Shin DM, Hong JH.
Drug Repurposing as an Antitumor Agent: Disulfiram-Mediated Carbonic Anhydrase 12 and Anion Exchanger 2 Modulation to Inhibit Cancer Cell Migration.Molecules 2019 Sep 19;24(18). pii: E3409.
Drug Repurposing as an Antitumor Agent: Disulfiram-Mediated Carbonic Anhydrase 12 and Anion Exchanger 2 Modulation to Inhibit Cancer Cell Migration.Molecules 2019 Sep 19;24(18). pii: E3409.
Lee DU, Park JY, Kwon S, Park JY, Kim YH, Khang D, Hong JH.
Lee DU, Park JY, Kwon S, Park JY, Kim YH, Khang D, Hong JH.
Apoptotic lysosomal proton sponge effect in tumor tissue by cationic gold nanorods. Nanoscale 2019 Oct 11.
Apoptotic lysosomal proton sponge effect in tumor tissue by cationic gold nanorods. Nanoscale 2019 Oct 11.
Lee DU, Hong JH.
Lee DU, Hong JH.
The Fundamental Role of Bicarbonate Transporters and Associated Carbonic Anhydrase Enzymes in Maintaining Ion and pH Homeostasis in Non-Secretory Organs. International Journal of molecular sciences. 2020 Jan 4;21(1).
The Fundamental Role of Bicarbonate Transporters and Associated Carbonic Anhydrase Enzymes in Maintaining Ion and pH Homeostasis in Non-Secretory Organs. International Journal of molecular sciences. 2020 Jan 4;21(1).
Lee DU, Hong JH.
Lee DU, Hong JH.
Nanoparticle-Mediated Therapeutic Application for Modulation of Lysosomal Ion Channels and Functions. Pharmaceutics. 2020. 12, 217; doi:10.3390 (Mar 02)
Nanoparticle-Mediated Therapeutic Application for Modulation of Lysosomal Ion Channels and Functions. Pharmaceutics. 2020. 12, 217; doi:10.3390 (Mar 02)
Kang JY, Kang N, Yang YM, Hong JH, Shin DM.
Kang JY, Kang N, Yang YM, Hong JH, Shin DM.
The Role of Ca2+-NFATc1 Signaling and Its Modulation on Osteoclastogenesis. International Journal of molecular sciences. 2020 May 21;21(10):3646.
The Role of Ca2+-NFATc1 Signaling and Its Modulation on Osteoclastogenesis. International Journal of molecular sciences. 2020 May 21;21(10):3646.
Son ES, Park JW, Kim YJ, Jeong SH, Hong JH, Kim SH, Kyung SY.
Son ES, Park JW, Kim YJ, Jeong SH, Hong JH, Kim SH, Kyung SY.
Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke extract. Toxicol In Vitro. 2020 Sep;67:104883.
Effects of antioxidants on oxidative stress and inflammatory responses of human bronchial epithelial cells exposed to particulate matter and cigarette smoke extract. Toxicol In Vitro. 2020 Sep;67:104883.
Hwang S, Shin DM, Hong JH.
Hwang S, Shin DM, Hong JH.
Protective Role of IRBIT on Sodium Bicarbonate Cotransporter-n1 for Migratory Cancer Cells, Pharmaceutics. 2020 Aug 27;12(9):E816.
Protective Role of IRBIT on Sodium Bicarbonate Cotransporter-n1 for Migratory Cancer Cells, Pharmaceutics. 2020 Aug 27;12(9):E816.
Ji M, Ahn CB, Son KH, Hong JH.
Ji M, Ahn CB, Son KH, Hong JH.
Cellular channelopathy mediated by hypergravity: IL-6-mediated Nkcc1 activation and enhanced Trpm2 expression in rat atrium. Cell & Tissue Research 2020 Nov 7. doi: 10.1007/s00441-020-03299-2.
Cellular channelopathy mediated by hypergravity: IL-6-mediated Nkcc1 activation and enhanced Trpm2 expression in rat atrium. Cell & Tissue Research 2020 Nov 7. doi: 10.1007/s00441-020-03299-2.
Hwang S, Shin DM, Hong JH.
Hwang S, Shin DM, Hong JH.
Intracellular Ca2+-Mediated AE2 Is Involved in the Vectorial Movement of HaCaT Keratinocyte. International Journal of molecular sciences. 2020 Nov 10;21(22):E8429.
Intracellular Ca2+-Mediated AE2 Is Involved in the Vectorial Movement of HaCaT Keratinocyte. International Journal of molecular sciences. 2020 Nov 10;21(22):E8429.
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