Publications

Hye Ung Jeong, Changmin Oh, Hyo-Eon Jin,* and Jong-Wha Jung* “FDA approved peptide drugs in 2023” Yakhak Hoeji 2024, 68(2):79-83. (2024/05/01)

Soo Hyun Kim, Hyun Jung Kim, Jong-Wha Jung, Sooyoung Chung*, and Gi Hoon Son* “Transcriptomic data of human adrenocortical NCI-H295R cells treated with cortisol biosynthesis inhibitors” Data in Brief 2024, 52, 109948. (2024/02/01)

Hana Cho, Ahee Yun, Joohee Kim, Eunjeong Park, Jong-Wha Jung, Sooyoung Chung*, and Gi Hoon Son* “Functional characterization of circadian nuclear receptors REV-ERBαand REV-ERBβ in human osteosarcoma cell cultures” Int. J. Mol. Sci. 2024, 25(2), 770-783. (2024/01/07)

Changmin Oh, Ji Hyeon Im, Munhyung Bae, and Jong-Wha Jung* “Asymmetric synthesis of four stereoisomers of 2,2-dimethyl-3-hydroxy-4-(1’-angeloyloxy)-6-acetylchromane from Ageratina grandifolia and plausible absolute stereochemistry of the natural product” ACS Omega 2023, 8(4), 37384-37390. (2023/09/26)

Soo Hyun Kim, Gi Hoon Son, Joo Young Seok, Sung Kook Chun, Hwayoung Yun, Jaebong Jang, Young-Ger Suh, Kyungjin Kim, Jong-Wha Jung,* and Sooyoung Chung* “Identification of a novel class of cortisol biosynthesis inhibitors and its implications in a therapeutic strategy for hypercortisolism” Life Sciences 2023, 325, 121744. (2023/04/29)

Ujjwala Karmacharya, and Jong-Wha Jung* “Small molecule inhibitors for Unc-51 like autophagy activating kinase targeting autophagy in cancer” Int. J. Mol. Sci. 2023, 24(2), 953-966. (2023/01/04)

Seoyoung Jo, Bohun Kang, and Jong-Wha Jung* “Microwave-assisted Cu-catalyzed diaryletherification for facile synthesis of bioactive prenylated diresorcinols” Molecules 2022, 28(1), 62-70. (2022/12/21)

Aneta Grycová, Hansol Joo, Vítězslav Maier, Peter Illés, Barbora Vyhlídalová, Karolína Poulíková, Lucia Sládeková, Petr Nádvorník, Radim Vrzal, Lenka Zemánková, Petra Pečinková, Martin Poruba, Iveta Zapletalová, Rostislav Večeřa, Pavel Anzenbacher, Jiří Ehrmann, Peter Ondra, Jong-Wha Jung, Sridhar Mani, and Zdeněk Dvořák "Targeting the aryl hydrocarbon receptor with microbial metabolite mimics alleviates experimental colitis in mouse" J. Med. Chem. 65(9), 6859-6868. (2022/5/12)

Gyubi Kim, Hansol Joo, and Jong-Wha Jung* “Recent Advances in Development of Glutaminase Inhibitors as Anticancer Agents” Yakhak Hoeji 2021, 65(5), 335-404. (2021/11/01)

Yong Uk Jeong, Hyo-Eon Jin, Hye Young Lim, Goyeong Choi, Hansol Joo, Bohun Kang, Ga-Hyun Lee, Kwang-Hyeon Liu, Han-Joo Maeng, Sooyoung Chung, Gi Hoon Son,* and Jong-Wha Jung* “Development of Non-Ethoxypropanoic Acid Type Cryptochrome Inhibitors with Circadian Molecular Clock-Enhancing Activity by Bioisosteric Replacement” Pharmaceuticals 2021, 14, 496. (2021/05/24) 

Yu-Gyeong Kim, Yunsu Lee, Joo Hee Kim, Sun-Young Chang, Jong-Wha Jung, and Woo-Jae Chung,* and Hyo-Eon Jin* “Self-Assembled Multi-Epitope Peptide Amphiphiles Enhance the Immune Response against Enterovirus 71” Nanomaterials 2020, 10(00), 2342. (2020/11/25)

Yu-Gyeong Kim, Yunsu Lee, Jong-Wha Jung, and Hyo-Eon Jin* “Epitope peptide amphiphile-based nanofiber as an effective vaccine for viral infectious disease” Journal of Nanoscience and Nanotechnology 2020, 20(9), 5329-5332. (2020/09/01)

Goyeong Choi, Seoyoung Jo, Juyeon Mun, Yonguk Jeong, Seok-Ho Kim, and Jong-Wha Jung* “Unexpected rearrangement of N-allyl-2-phenyl-4,5-dihydrooxazole-4-carboxamides to construct aza-quaternary carbon centers” Molecules 2019, 24(24), 4495-4507. (2019/12/08) 

Jiyoon Seok, Soo‑Hyun Yoon, Sun‑Hee Lee, Jong-Wha Jung, and You Mie Lee* “The oncometabolite d‑2‑hydroxyglutarate induces angiogenic activity through the vascular endothelial growth factor receptor 2 signaling pathway” Int. J. Oncol. 2019, 54(2), 753-763. (2019/02/01)

Hyo Kyeong Cha, Sooyoung Chung, Hye Young Lim, Jong-Wha Jung, and Gi Hoon Son* “Small molecule modulators of the circadian molecular clock with implications for neuropsychiatric diseases” Front. Mol. Neurosci. 2019, 11:496. (2019/01/21) 

Yue Yuan, Jong-Wha Jung, Seung-Yong Seo* “Enantioselective synthesis and absolute configuration determination of hydroxywilfordic acid in sesquiterpene pyridine alkaloids” Org. Biomol. Chem. 2019, 17, 44-48. (2019/01/07) 

Minjun Kim, Jaebong Jang, Goyoung Choi, Sungkyun Chung, Changjin Lim, Joonseong Hur, Hyun Su Kim, Younghwa Na, Woo Sung Son, Young-Ger Suh, Jong-Wha Jung,* and Seok-Ho Kim* “Conversion of Medium-Sized Lactams to a-Vinyl or a-Acetylenyl Azacycles via N,O-Acetal TMS Ethers” Molecules 2018, 23(11), 3023-. (2018/09/20) 

Jong-Wha Jung, Nam-Jung Kim, Hwayoung Yun,* and Young Taek Han* “Recent Advances in Synthesis of 4-Arylcoumarins” Molecules 2018, 23(10), 2417-. (2018/09/20)

Jaebong Jang, Sooyoung Chung, Youjeong Choi, Hye Young Lim, Yeongeon Son, Sung Kook Chun, Gi Hoon Son, Kyungjin Kim, Young-Ger Suh*, and Jong-Wha Jung* “The cryptochrome inhibitor KS15 enhances E-box-mediated transcription by disrupting the feedback action of a circadian transcription-repressor complex” Life Sciences 2018, 200, 49-55. (2018/05/01) 

Chansik Yang, Sugyeong Kwon, Se-Jong Kim, Minseon Jeong, Ji-young Park, Dongeun Park, Soon Jun Hong, Jong-Wha Jung*, and Chungho Kim* “Identification of Indothiazinone as a Natural Antiplatelet Agent” Chem. Biol. Drug Des. 2017, 90(5), 873-882. (2017/11/01) 

Jong-Wha Jung, Seok-Ho Kim,* and Young-Ger Suh* “Advances in the Aza-Claisen Rearrangement-Induced Ring Expansion Strategy” Asian J. Org. Chem. 2017, 6(9), 1117-1129. (2017/09/01) 

Young-Taek Han, Jong-Wha Jung, and Nam-Jung Kim* “Recent Advances in the Synthesis of Biologically Active Cinnoline, Phthalazine and Quinoxaline Derivatives” Curr. Org. Chem. 2017, 21(14), 1265-1291.(2017/06) 

Miseon Ryu, Minjun Kim, Minseon Jeong, Jaebong Jang, Minyoung Lee, Hyo-Eon Jin* and Jong-Wha Jung* “Studies on the Alkylation of Phenolate in an Organofluorine Solvent and Its Application to the Synthesis of Myrsinoic Acid A and E” Syn. Commun. 2017, 47(8), 818-824. (2017/02/01) 

I-Rang Lim, Hyung Joon Joo, Minseon Jeong, Jong-Ho Kim, Seung-Cheol Choi, Chungho Kim, Jong-Wha Jung and Soon Jun Hong* “Talin modulation by a synthetic N-acylurea derivative reduces angiogenesis in human endothelial cells” Int. J. Mol. Sci. 2017, 18(1), 221-234; doi:10.3390/ijms18010221. (2017/01/22) 

Eun-Ju Yang, Minjun Kim, Ji Eun Woo, Taeho Lee, Jong-Wha Jung*, and Kyung-Sik Song* “The comparison of neuroprotective effects of isoliquiritigenin and its Phase I metabolite against glutamate-induced HT22 cell death” Bioorg. Med. Chem. Lett. 2016, 26(23), 5639-5643. (2016/12/01). 

Miyeon Cho, Seok Won Jung, Soomin Lee, Kuwon Son, Gyu Hwan Park, Jong-Wha Jung, Yu Su Shin, Taegun Seo, Hyosun Cho, and Hyojeong Kang “Genipin Enhances Kaposi’s sarcoma-associated herpesvirus Genome Maintenance” PLOS ONE 2016, 11(10):e0163693, doi:10.1371/journal.pone.0163693. (2016/10/13). 

Seok-Ho Kim, Won-Il Lee, Seon-Mi Kim, Jae-Kyung Jung, Jaebong Jang, Jaehoon Sim, Jong-Wha Jung*, and Young-Ger Suh* “Studies on the Aza-Claisen Rearrangement of 7 to 9-Membered Vinylazacycles” Heterocycles  2016, 92(5), 886-899. (2016/04/27) 

Geun Hye Hwang, Jung Min Ryu, Yu Jin Jeon, Joon hyeok Choi, Ho Jae Han, You-Mie Lee, Sangkyu Lee, Jong-Sup Bae, Jong-Wha Jung, Woochul Chang, Lark Kyun Kim, Jun-Goo Jee*, and Min Young Lee* “The role of thioredoxin reductase and glutathione reductase in plumbagin-induced, reactive oxygen species-mediated apoptosis in cancer cell lines” Eur. J. Pharmacol.  2015, 765, 384-393. (2015/10/15) 

Sarah K. Edwards, Toshikazu Ono, Shenliang Wang, Wei Jiang, Raphael Franzini, Jong-Wha Jung, Ke Min Chan, and Eric T. Kool* “Fluorogenic Real-time Reporters of the Repair of Oxidative DNA Damage” ChemBioChem 2015, 16(11), 1637-1646. (2015/06/12) 

Sugyeong Kwon, Youngtaek Han,* and Jong-Wha Jung* “Studies on the Synthesis of Indothiazinone and Its Derivatives via Direct 3-Acylation of Indole” Syn. Commun. 2015, 45, 1662-1668. (2015/04/15) 

Robert C. Spitale,  Ryan A. Flynn,  Qiangfeng Cliff Zhang,  Pete Crisalli,  Byron Lee,  Jong-Wha Jung,  Hannes Y. Kuchelmeister, Pedro J. Batista,  Eduardo A. Torre,  Eric T. Kool* and  Howard Y. Chang* “Structural imprints in vivo decode RNA regulatory mechanisms” Nature 2015, 519, 486-490. (2015/03/18) 

Sung Kook Chun, Jaebong Jang, Sooyoung Chung, Hwayoung Yun, Nam-Jung Kim, Jong-Wha Jung, Gi Hoon Son, Young-Ger Suh,* and Kyungjin Kim* “Identification and Validation of Cryptochrome Inhibitors That Modulate the Molecular Circadian Clock” ACS Chem. Biol. 2014, 9(3), 703–710. (2014/03/21) 

Won-Il Lee, Jong-Wha Jung, Jaebong Jang, Hwayoung Yun, and Young-Ger Suh* “Synthesis of 5,6-dihydrophenanthridines via N,O-acetal TMS ethers” Tetrahedron Lett.  2013, 54(38), 5167-5171. (2013/09/18) 

Won-Il Lee, Jong-Wha Jung, Jaehoon Sim, Hongchan An, and Young-Ger Suh* “Microwave-assisted synthesis of 3-substituted indoles via intramolecular arene–alkene coupling of o-iodoanilino enamines” Tetrahedron  2013, 69(35), 7211-7219. (2013/09/02) 

Jong-Wha Jung, Sarah K. Edwards, and Eric T. Kool* “Selective Fluorogenic Chemosensors for Distinct Classes of Nucleases” ChemBioChem  2013, 14(4), 440-444. (2013/03/04) 

Nam-Jung Kim, Fu-Nan Li, Jin Hee Lee, Seul-gi Park, Kyeojin Kim, Changjin Lim, Young Taek Han, Hwayoung Yun, Jong-Wha Jung, Hyeung-geun Park, Hee-Doo Kim, Byoung Young Woo, Song Seok Shin, Sun-Young Kim, Jin Kyu Choi, Yeon-Su Jeong, Yanghui Park, Young-Ho Park, Dae-Duk Kim, Sun Choi, and Young-Ger Suh* “Heterocycle-linked Phenylbenzyl Amides as Novel TRPV1 Antagonists and Their TRPV1 Binding Modes: Constraint-Induced Enhancement of In Vitro and In Vivo Activities” Chem. Asian J.  2013, 8(2), 400-409. (2013/02/01)

Jaejoon Sim, Hwayoung Yun, Jong-Wha Jung, Sujin Lee, Nam-Jung Kim and Young-Ger Suh* “Chiral auxiliary-assisted chiral transfer via microwave-accelerated aza-Claisen rearrangement: a short synthesis of (+)-1-hydroxyquinolizidinone” Tetrahedron Lett. 2012, 53(36), 4813-4815. (2012/09/05) 

Jaebong Jang, Jong-Wha Jung, Jaeseung Ahn, Jaehoon Sim, Dong-Jo Chang, Dae-Duk Kim and Young-Ger Suh* “Asymmetric formal synthesis of schulzeines A and C” Org. Biomol. Chem. 2012, 10(27), 561-568. (2012/07/21) 

Sujin Lee, Sony Marharjan, Jong-Wha Jung, Nam-Jung Kim, Kyeojin Kim, Young Taek Han, Changjin Lim, Hyun-Jung Choi, Young-Geun Kwon, and Young-Ger Suh* “Novel Human Umbilical Vein Endothelial Cells (HUVEC)-Apoptosis Inhibitory Phytosterol Analogues: Insight into Their Structure- Activity Relationships” Arch. Pharm. Res. 2012, 35(3), 455-460. (2012/03/01) 

Young-Ger Suh*, Yong-Sil Lee, Seok-Ho Kim, Jae-Kyung Jung, Hwayoung Yun, Jaebong Jang, Nam-Jung Kim and Jong-Wha Jung* “A Stereocontrolled Access to Functionalized Macrolactams via Aza-Claisen Rearrangement” Org. Biomol. Chem. 2012, 10(3), 561-568. (2012/01/21) 

Young-Ger Suh*, Jaebong Jang, Hwayoung Yun, Sae Mi Han, Dongyun Shin, Jae-Kyung Jung and Jong-Wha Jung* “Expedient Synthesis of Chiral Homoallylamines via N,O-Acetal TMS Ethers and Its Application” Org. Lett. 2011, 13(21), 5920-5923. (2011/11/04) 

Young Taek Han, Nam-Jung Kim, Jong-Wha Jung, Hwayoung Yun, Sujin Lee, and Young-Ger Suh* “A Versatile Synthetic Approach to Grandisol Monoterpene Pheromone” Arch. Pharm. Res. 2011, 34(9), 1437-1442. (2011/09/01) This work was selected by editors in Arch. Pharm. Res. 2011, 34, 1399-1402. 

Hongchan An, Nam-Jung Kim, Jong-Wha Jung, Hannah Jang, Jong-Wan Park and Young-Ger Suh* “Design, Synthesis and Insight into the Structure-Activity Relationship of 1,3-Disubstituted Indazoles as Novel HIF-1 Inhibitors” Bioorg. Med. Chem. Lett. 2011, 21(21), 6297-6300. (2011/11/01)

Nam-Jung Kim, Hyunyoung Moon, Taesun Park, Hwayoung Yun, Jong-Wha Jung, Dong-Jo Chang, Dae-Duk Kim, and Young-Ger Suh* “Concise and Enantioselective Total Synthesis of 15-Deoxy-D12,14-Prostaglandin J2” J. Org. Chem. 2010, 75(21), 7458-7460. (2010/11/05) 

Jong-Wha Jung, Jaebong Jang, Seung-Yong Seo, Jae-Kyung Jung, and Young-Ger Suh* “Total synthesis of rodgersinol: a survey of the Cu(II)-mediated coupling of ortho-substituted phenols” Tetrahedron 2010, 66(34), 6826-6831. (2010/08/21) 

Yong-Sil Lee, Jong-Wha Jung, Seok-Ho Kim, Jae-Kyung Jung, Seung-Mann Paek, Nam-Jung Kim, Dong-Jo Chang, Jeeyeon Lee, and Young-Ger Suh* “First Total Synthesis and Structural Confirmation of Fluvirucinine A2 via an Iterative Ring Expansion Strategy” Org. Lett. 2010, 12(9), 2040-2043. (2010/05/07)

Young Taek Han, Seung-Mann Paek, Sujin Lee, Jong-Wha Jung, Jae-Kyung Jung, Seung-Yong Seo, Jeeyeon Lee, and Young-Ger Suh* “Thermodynamic equilibration in Pd(0)-catalyzed interconversion of highly constrained [2.1.2] bicyclic lactones: its mechanistic investigation” Tetrahedron Lett. 2010, 51(20), 2697-2699. (2010/05/19) 

Seung-Mann Paek, Nam-Jung Kim, Dongyun Shin, Jae-Kyung Jung, Jong-Wha Jung, Dong-Jo Chang, Hyunyoung Moon and Young-Ger Suh* “A Concise Total Synthesis of (+)-Tetrabenazine and (+)-a-Dihydrotetrabenazine” Chem.-Eur. J. 2010, 16(15), 4623 – 4628. (2010/03/16) 

Fu-Nan Li, Nam-Jung Kim, Dong-Jo Chang, Jaebong Jang, Hannah Jang, Jong-Wha Jung, Kyung-Hoon Min, Yeon-Su Jeong, Sun-Young Kim, Young-Ho Park, Hee-Doo Kim, Hyeung-Geun Park, Young-Ger Suh* “Synthesis and structural optimization of multiple H-bonding region of diarylalkyl (thio)amides as novel TRPV1 antagonist” Bioorg. Med. Chem. 2009, 17(24), 8149. (2009/12/15) 

Dong-Jo Chang, Eun-Young Yoon, Geon-Bong Lee, Soon-Ok Kim, Wan-Joo Kim, Young-Myeong Kim, Jong-Wha Jung, Hongchan Ahn and Young-Ger Suh* “Design, Synthesis and Identification of Novel Colchicine-Derived Immunosuppressant” Bioorg. Med. Chem. Lett. 2009, 10(15), 4416-4420. (2009/08/01) 

Hwayoung Yun, Seung-Mann Paek, Jong-Wha Jung, Nam-Jung Kim, Seok-Ho Kim and Young-Ger Suh* “First total syntheses of (-)-macrosphelides J and K and elucidation of their absolute configuration” Chem. Commun. 2009, 14(18), 2463-2465.(Issue Cover) (2009/05/14) 

Seung-Mann Paek, Hwayoung Yun, Nam-Jung Kim, Jong-Wha Jung, Dong-Jo Chang, Sujin Lee, Jakyung Yoo, Hyun-Ju Park and Young-Ger Suh* “Concise Syntheses of (+)-Macrosphelides A and B: Studies on the Macro-Ring Closure Strategy” J. Org. Chem. 2009, 74(2), 554-561. (2009/01/16) 

Young-Ger Suh*, Nam-Jung Kim, Bon-Woong Koo, Kwang-Ok Lee, Sung-Hyun Moon, Dong-Hyung Shin, Jong-Wha Jung, Seung-Mann Paek, Dong-Jo Chang, Funan Li, Hyun-Jin Kang, Tuong Vy Thi Le, Yu Na Chae, Chang Yell Shin, Mi-Kyung Kim, Joong In Lim, Jae-Sang Ryu and Hyun-Ju Park* “Design, Synthesis, and Biological Evaluation of Novel Constrained meta-Substituted Phenyl Propanoic Acids as Peroxisome Proliferator-Activated Receptor α and γ Dual Agonists” J. Med. Chem. 2008, 51(20), 6318-6333. (2008/10/23) 

Seung-Yong Seo, Jong-Wha Jung, Jae-Kyung Jung, Nam-Jung Kim, Young-Won Chin, Jinwoong Kim and Young-Ger Suh* “Concise Synthesis of Rodgersinol and Determination of the C-10 Absolute Configuration” J. Org. Chem. 2007, 72(2), 666-668. (2007/01/19) 

Seung-Mann Paek, Seung-Yong Seo, Seok-Ho Kim, Jong-Wha Jung, Yong-Sil Lee, Jae-Kyung Jung and Young-Ger Suh* “Concise Syntheses of (+)-Macrosphelides A and B” Org. Lett., 2005, 7(15), 3159-3162. (2005/07/21) 

Jong-Wha Jung, Dong-Yun Shin, Seung-Yong Seo, Seok-Ho Kim, Seung-Mann Paek, Jae-Kyung Jung and Young-Ger Suh* “A new entry to functionalized cycloalkylamines: diastereoselective intramolecular amidoalkylation of N,O-acetal TMS ether possessing allylsilane” Tetrahedron Lett. 2005, 46(4), 573-575. (2005/01/24)