6th Workshop and Symposium
Physics and Computation
in Immunology
in Immunology
28 – 30 September, 2026 | Yale University
28 – 30 September, 2026 | Yale University
This is an exciting time for immunology. Researchers strive to answer increasingly complex questions ranging from genetic, molecular, and cellular scales to human hosts and populations of humans and pathogens. Immune dynamics is equally challenging: fast processes of infection dynamics and affinity maturation generate long-term memory and evolutionary patterns of pathogens. Concepts rooted in physics and computational models play a key role in overcoming these challenges. Therefore, we aim to bring together scientists from different fields open to quantitative, cross-scale approaches in immunology.
Cellular scale: molecular and cellular biology of immune response.
Organismic scale: generation and maturation of immune repertoires, immune-pathogen evolution within hosts.
Population scale: global dynamics of pathogen-immune co-evolution, links to epidemiology.
This is the 6th in a series of meetings designed to build a coherent scientific community in quantitative immunology and adjacent fields. Previous meetings took place in Cargese (2022), Cologne (2020), Paris (2018), and Boston (2019, 2017).
The meeting will start in the afternoon of Monday the 28th with a tutorial session directed at young researchers and those who wish to enter the field. There will be thematic sessions on Tuesday and on Wednesday, and a poster session on Tuesday evening. We will close with a general discussion on Wednesday afternoon. The detailed program will be communicated to registered participants.
Location: The event will be held at 100 College st, New Haven. Tutorials and seminars will be on the 11th floor, and the poster session will be on the ground floor.
Monday, Sep 28 – tutorials
14:00 – 14:20 Armita Nourmohammad & John Tsang
Physics and Computation in Immunology: challenges and opportunities
14:30 – 15:30 Arup Chakraborty
The humoral immune system (molecular and cellular level)
15:30 – 16:00 coffee break
16:00 – 17:00 Aleksandra Walczak
Immune repertoires and memory responses (host level)
17:00 – 18:00 Michael Lässig
Immune-pathogen coevolution (population level)
Tuesday, Sep 29
9:00 – 9:10 Introduction and welcome
9:10 – 9:50 Ruslan Medzhitov
On learning and memory in the immune system
9:50 – 10:30 Hari Wong
Redefining self versus non-self discrimination
10:30 – 10:50 coffee break
10:50 – 11:30 Alon Oyler-Yaniv
A spatial solution to a temporal paradox: How cells collaborate to resist viral infection
11:30 – 12:10 Elizabeth Jerison
Probing the dynamics of inflammatory response
12:10 – 12:50 Andrew Wang
Biological strategies for mitigating time delay in negative feedback loops
12:50 – 14:20 lunch and discusion
14:20 - 15:00 John P. Barton
Forecasting viral evolution with genomic surveillance data
15:00 – 15:40 Narendra M. Dixit
Modeling antibody affinity maturation with multivalent antigens
15:40 – 16:00 coffee break
16:00 – 16:40 Noah Palm
Mapping uncharted landscapes of host-microbiota communication
16:40 – 17:20 Nicolas Chevrier
Decode and Recode Immunity
17:30 – 19:30 poster session + light snack and drinks
Wednesday, Sep 30
9:10 - 9:50 Hao Kueh
T cell signal sensing and integration
9:50 - 10:30 Ang Cui
Dictionary of immune responses to cytokines and chemokines at single-cell resolution
10:30 - 10:50 coffee break
10:50 - 11:30 Ned Wingreen
Collective dynamics in B cell affinity maturation
11:30 - 12:10 William DeWitt
Inference and design of evolutionary mechanisms in antibody response
12:10 - 12:50 Cole Tharp
Biophysical trade-offs in antibody evolution are resolved by conformation-mediated epistasis
12:50 - 14:20 lunch and discusion
14:20 - 15:00 Marta Łuksza
Predicting tumor evolution to design vaccines
15:00 - 15:40 Jamie Blundell
Massively parallel single-cell antigen mapping: from viral fingerprints to neoantigen discovery
15:40 - 16:20 Benjamin Greenbaum
Why is Innate Immunity important in Cancer Evolution?
16:20 - 16:30 Final remarks and poster awards
MIT
University of Cologne
Yale University
Yale University
ENS Paris
U of Pittsburgh
U of Chicago
Harvard University
U of Washington
Indian Institute of Science
Memorial Sloan Kettering Cancer Center
U of Chicago
Yale University
Memorial Sloan Kettering Cancer Center
Yale University
Harvard University
Yale University
UC San Francisco
Yale University
Princeton University
MIT
The meeting is limited to around 120 participants. Registration is free of charge.
The registration deadline is September 6
Please provide details on your poster submission by September 16.
Poster format: A0 – 841mm x 1189mm (W x H)
A detailed schedule will be communicated to registered participants after acceptance.
Coffee breaks and lunches on Tue and Wed are included.
If you need a letter of acceptance for visa purposes, please let us know.
By registering, you agree to our Code of Conduct.
Participants should arrange accommodation for themselves. Some of the hotels at convenient locations in New Heaven are:
By Train: New Haven is served by both Metro North (511 from New York; 800-690-5114) and Amtrak (800-USA-RAIL). Taxi or a ride-share will bring you the short distance to the conference location or to your hotel.
By Air: Tweed-New Haven airport, serviced by Avelo, is the closest to campus. Bradley International Airport is just north of Hartford.
The three New York airports offer the widest range of airlines and flights, as well as more advantageous fares.
JFK is about two hours away from New Haven. Public transportation via Airtrain and Subway can take you to midtown Manhattan in 50 minutes; from there you can take Metro North or Amtrak to New Haven.
La Guardia is slightly closer to New Haven and public transportation into Manhattan is by bus and subway.
Newark Liberty International has the advantage of an Amtrak station on the main line to New Haven.
Please be aware that customs processing can take up to (2) hours in major airports. Keep this in mind as you are scheduling travel plans.
By Car/Ride-Share: If you choose to travel by car, parking will be available at the hotel. There are also several garages in New Haven listed here: https://parknewhaven.com/parking/
Yale Shuttle: The Yale Shuttle operates a full campus service within New Haven with live tracking at https://yaleshuttle.doublemap.com/map/
Airport Shuttle: GO Airport Shuttle Connecticut provides a shared-ride service and private limousine service between John F. Kennedy International (JFK) and La Guardia Airport (LGA) and Yale University Reservations are required to book and can be made here: https://2theairport.com/reservations/?portal=YALE
Questions? Please reach out to us!