Peer reviewer & preLights

• eLife, eLife Sciences Publications, Ltd

• Nature Communications, Nature Publishing group

• Journal of Cachexia, Sarcopenia and Muscle, John Wiley & Sons

• Open Biology, The Royal Society Publishing

• Protein & Cell, Springer and Higher Education Press

• Current Opinion in Pharmacology, Elsevier, Appointed as a Reviewer by Dr. Gustavo Duque

• Cellular Signalling, Elsevier, Appointed as a Reviewer by Co-Editor Dr. Andrea Babelova

• Journal of Cell Communication and Signaling, Springer Nature, Switzerland

• Biology, MDPI, Basel, Switzerland

• Biomolecules, MDPI, Basel, Switzerland

• Experimental Gerontology, Elsevier, Netherlands

• The FASEB journal, Federation of American Societies for Experimental Biology, John Wiley & Sons

• Journal of Molecular and Cellular Cardiology (appointed as Junior Reviewer by Editor Dr. Jennifer Davis)

• Frontiers in Cardiovascular Medicine, Swiss Federal Institute of Technology in Lausanne (EPFL), Switzerland.

• Cells, MDPI, Basel, Switzerland 

• Clinical Science (Portland Press), The Biochemical Society, London, UKs

• International Journal of Molecular Sciences, MDPI, Basel, Switzerland

• Genes, MDPI, Basel, Switzerland 

• Biomedicines, MDPI, Basel, Switzerland 

• Annals of Translational Medicine

• Medical Science Monitor

• Early Career Reviewer* at Journal of Biological Chemistry (JBC), American Society for Biochemistry and Molecular Biology, appointed as Early Career Reviewer *Learn more about ECR at JBC

Being a PreLighter

I’m part of the carefully selected group of early-career researchers called PreLights community from The Company of Biologists, UK. Visit my profile: https://prelights.biologists.com/profiles/osvaldo-contreras/.

My Highlights:

1. https://prelights.biologists.com/highlights/a-transcriptional-switch-governing-fibroblast-plasticity-underlies-reversibility-of-chronic-heart-disease/

Here, we discussed why mammalian cardiac regeneration and repair do not occur in adults and account for new potential ways of improving heart failure and fibrosis. By Osvaldo Contreras & Alex Ward.

2. https://prelights.biologists.com/highlights/human-skeletal-muscle-cd90-fibro-adipogenic-progenitors-are-associated-with-muscle-degeneration-in-type-2-diabetic-patients/

Here, we highlighted the unknown role of skeletal muscle FAP cells in degenerative settings, including disease, obesity and type 2 diabetes. By Osvaldo Contreras & Nicolás Collao.

3. https://prelights.biologists.com/highlights/bromodomain-inhibition-blocks-inflammation-induced-cardiac-dysfunction-and-sars-cov2-infection-in-pre-clinical-models/

Here, we summarized the last finding of the damaging effects of SARS-CoV2 in the heart and explain the last wonderful article published in BiorXiv from James Hudson Lab at the QIMR Berghofer Medical Research Institute. By Alex Ward & Osvaldo Contreras

4. Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development

In this Prelight, we summarized why and how D'Amato and Krysty Red-Horse Labs used scRNA-seq combined with endothelial cell lineage-tracing to explore for the first time the dual origins of coronary blood vessels during mouse and human development. By Yen Tran & Osvaldo Contreras

5. Multiscale light-sheet organoid imaging framework

In this exciting new preprint, Liberali and colleagues leverage their extensive organoid-imaging knowledge [3] to present LSTree (an acronym for Light-Sheet Tree), a light-sheet imaging framework to analyze and digitally visualize organoids. LST goes from image pre-processing, cell lineage tracking, and segmentation to analytical tools to extract morphological and microscopy features. The authors used this light-sheet microscopy-based imaging framework to analyze and reconstruct, at an unprecedented spatiotemporal resolution, the cell growing dynamics and cell lineage relationships during intestinal organoid development.