Publications

Golconda, P., Andrade-Medina, M., Matrenec, R., McLachlan, A., and Oberstein, A. (2024). The Epithelial-to-Mesenchymal Transition Supports HCMV Infection and Biosynthesis in Mammary Epithelial Cells Through Two Distinct Mechanisms. Preprint at bioRxiv, https://doi.org/10.1101/2024.08.12.607657 https://doi.org/10.1101/2024.08.12.607657.

Andrade-Medina, M., Greco, T.M., Cristea, I.M., and Oberstein, A. (2024). ARPE-19 Epithelial Cells Fail To Initiate Type-I Interferon Signaling in Response to Human Cytomegalovirus Infection. Preprint at bioRxiv, https://doi.org/10.1101/2024.08.01.606090 https://doi.org/10.1101/2024.08.01.606090.

Golconda, P., Andrade-Medina, M., and Oberstein, A. (2024). Subconfluent ARPE-19 Cells Display Mesenchymal Cell-State Characteristics and Behave like Fibroblasts, Rather Than Epithelial Cells, in Experimental HCMV Infection Studies. Viruses 16, 49. https://doi.org/10.3390/v16010049.

Park, J., Gill, K.S., Aghajani, A.A., Heredia, J.D., Choi, H., Oberstein, A., and Procko, E. (2020). Engineered receptors for human cytomegalovirus that are orthogonal to normal human biology. PLOS Pathogens 16, e1008647.

Nogalski, M.T., Solovyov, A., Kulkarni, A.S., Desai, N., Oberstein, A., Levine, A.J., Ting, D.T., Shenk, T., and Greenbaum, B.D. (2019). A tumor-specific endogenous repetitive element is induced by herpesviruses. Nat Commun 10, 1–13.

Wu, K., Oberstein, A., Wang, W., and Shenk, T. (2018). Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts. PNAS 115, E9889–E9898.

Oberstein, A., and Shenk, T. (2017). Cellular responses to human cytomegalovirus infection: Induction of a mesenchymal-to-epithelial transition (MET) phenotype. PNAS 201710799.

Oberstein, A., Perlman, D.H., Shenk, T., and Terry, L.J. (2015). Human cytomegalovirus pUL97 kinase induces global changes in the infected cell phosphoproteome. Proteomics 15, 2006–2022.

Mathias, R.A., Greco, T.M., Oberstein, A., Budayeva, H.G., Chakrabarti, R., Rowland, E.A., Kang, Y., Shenk, T., and Cristea, I.M. (2014). Sirtuin 4 Is a Lipoamidase Regulating Pyruvate Dehydrogenase Complex Activity. Cell 159, 1615–1625.

Oberstein, A., Jeffrey, P.D., and Shi, Y. (2007). Crystal Structure of the Bcl-XL-Beclin 1 Peptide Complex: Beclin 1 is a novel BH3-Only protein. Journal of Biological Chemistry 282, 13123–13132.

Wu, Z., Yan, N., Feng, L., Oberstein, A., Yan, H., Baker, R.P., Gu, L., Jeffrey, P.D., Urban, S., and Shi, Y. (2006). Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nature Structural & Molecular Biology 13, 1084–1091.

Oberstein, A., Pare, A., Kaplan, L., and Small, S. (2005). Site-specific transgenesis by Cre-mediated recombination in Drosophila. Nature Methods 2, 583–585.

Ochoa-Espinosa, A., Yucel, G., Kaplan, L., Pare, A., Pura, N., Oberstein, A., Papatsenko, D., and Small, S. (2005). The role of binding site cluster strength in Bicoid-dependent patterning in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 102, 4960–4965.

Andrioli, L.P., Oberstein, A.L., Corado, M.S.G., Yu, D., and Small, S. (2004). Groucho-dependent repression by Sloppy-paired 1 differentially positions anterior pair-rule stripes in the Drosophila embryo. Developmental Biology 276, 541–551.

Andrioli, L.P.M., Vasisht, V., Theodosopoulou, E., Oberstein, A., and Small, S. (2002). Anterior repression of a Drosophila stripe enhancer requires three position-specific mechanisms. Development 129, 4931–4940.