Embedded Files
國立陽明交通大學, 生物醫學工程學院, 生物醫學影像暨放射學系
National Yang Ming Chiao Tung University, College of Biomedical Science and Engineering, Department of Biomedicine Imaging and Radiological Sciences (NYCU, BIRS)
Principal Investigator: Yu-Chan Chang (張御展), Ph.D.
Principal Investigator: Yu-Chan Chang (張御展), Ph.D.
Current Positions
Department of Biomedical Imaging and Radiological Science (BIRS),
National Yang Ming Chiao Tung University
Associate Professor, Appointed: Aug, 2024-present
Work Experience
Postdoctoral fellow
July. 2017 to July. 2020
Genomics Research Center, Academia Sinica, Taipei, Taiwan
Institute of Pathology and Parasitology,
National Defense Medical Center
Adjunct Assistant Professor, Appointed: Aug, 2021-July. 2024
Department of Biomedical Imaging and Radiological Science (BIRS),
National Yang Ming Chiao Tung University
Assistant Professor, Appointed: Aug, 2020- July. 2024
CONTACT INFORMATION
yuchanchang@nycu.edu.tw
國立陽明交通大學,陽明校區實驗大樓4樓B308室
Address: Biomedical Engineering Building 442, No.155, Sec.2, Linong Street, Taipei, 112, Taiwan
Tel: +886-2-2826-7064 (NYCU)
Research areas:
Cancer Metabolism, Radiobiology, Cellular Imaging, Oncology
Expertise and Research Interests
"Our basic science research investigates how adaptive metabolism reprograms cancer transcripts/proteomes during metastasis/resistance. Clinical research focuses on identifying the mechanisms responsible for various common cancers such as lung cancer, breast cancer, brain cancer, gastrointestinal tract, Histomorphology and molecular pathogenesis of liver and pancreaticobiliary diseases. This laboratory also provides translational pathology research support to our department and other NYCU and TVGH researchers."
News
01.27.2021 張御展老師榮獲”科技部補助大專院校延攬特殊優秀人才補助”
10.26.2022 張御展老師實驗室論文榮獲”國立陽明交通大學校內111年第一季重要期刊論文”
11.01.2022 大專生_何兆璟榮獲”白金科技優秀學士生獎” (110下)
12.08.2022 張御展老師榮獲 ”財團法人沈力揚教授醫學教育獎學紀念基因會補助”
02.23.2023 大專生_何兆璟榮獲”白金科技優秀學生獎” (111上)
03.09.2023 碩士生_林柏玄研究論文榮獲”37th 生會年會大會演講”
碩士生_蔡惠宇研究論文榮獲”37th 生會年會海報展示”
03.23.2023 碩士生_林柏玄榮獲 “優秀學生獎
04.27.2023 碩士生_林柏玄榮獲”白金科技優秀碩士生獎” (111下)
05.09.2023 碩士生_林柏玄研究論文榮獲第二屆Merck年輕人科學競賽壁報組複選 (癌症領域)
碩士生_蔡惠宇研究論文榮獲第二屆Merck年輕人科學競賽壁報組複選(生物領域)
05.10.2023 張御展老師榮獲 ”111學年度學院英語授課教學獎”
05.29.2023 碩士生_林柏玄研究論文榮獲第二屆Merck年輕人科學競賽壁報組複選。生物領域_癌症研究組_新星獎
https://www.merckgroup.com/tw-zh/news/merck-announces-the-2nd-merck-young-scientist-award-winners.html
06.06.2023 碩士生_林柏玄研究論文榮獲111學年度學術論文研討會_優等
08.25.2023 張御展老師榮獲 ”第十九屆榮總台灣聯合大學合作研究成果發表會壁報組競賽臨床醫學組I第三名”
12.14.2023 張御展老師於新竹竹北高中進行學群學系講座, 題目:有圖有真相:工作細胞.
12.28.2023 張御展老師榮獲"111年度第二梯次教研人員國際化優良成果獎勵"
01.04.2024 張御展老師擔任醫學院重要論文專題演講_評論者, 講評題目: Radiologic Patterns Determine the Outcomes of Initial and Subsequent Transarterial Chemoembolization in Intermediate-Stage Hepatocellular Carcinoma (臨醫所_黃怡翔 教授)
01.15.2024-03.29-2024 IIPP學生Thomas/Jade 加入實驗室.
03.23-24.2024 第38屆生醫年會 分子影像學會 郭翰錫 海報組第一名
葉佳穎 口頭組佳作
05.07.2024 碩士生_葉佳穎研究論文榮獲第三屆Merck年輕人科學競賽壁報組複選 (癌症研究組)
碩士生_郭翰錫研究論文榮獲第三屆Merck年輕人科學競賽壁報組複選 (神經與免疫醫學組)
05.20.2024-06.25.2024 IIPP學生Veronica 加入實驗室.
06.07.2024 碩士生_葉佳穎研究論文榮獲112學年度學術論文研討會_優等
碩士生_郭翰錫研究論文榮獲111學年度學術論文研討會_佳作
08.01.2024 碩士生_郭翰錫考取國立陽明交通大學 生物醫學影像暨放射科學系 博士班錄取
09.01.2024 博士生_郭翰錫獲得_國科會博士生研究獎學金補助
10.11.2024 張御展老師於台中私立曉明女中進行學群學系講座, 題目:有圖有真相:工作細胞.
11.20.2024 張御展老師參與高中端諮詢交流會議-學習歷程資料對接大學人才培力要求
11.29.2024 張御展老師參與嘉義區-113學年度協作共好計畫
02.24.2025 張御展老師榮獲 IJMS Young Investigator Award (2024).
https://www.mdpi.com/journal/ijms/awards/2671
03.23.2025 碩士生_林又妤研究論文榮獲第38屆生醫年會 分子影像學會_海報組第三名
03.29.2025 張御展老師榮獲 114年台北市社會優秀青年
05.17.2025 碩士生_林又妤研究論文榮獲Merck年輕人科學競賽壁報組優等獎 (癌症免疫醫學組)
.............to be continued
1. (2016/08/01-2019/7/31) Ministry of Science and Technology MOST: 106-2320-B-038-035-MY3 Molecular Mechanisms of Secretory RAB GTPase 3C in Promoting Colon Cancer Metastasis, PI: Chi-Long Chen
2. (2017/08/01-2020/7/31) Ministry of Science and Technology MOST 107-2320-B-001 -016 -MY3. Molecular Mechanisms of Aldolase A Non-enzymatic Function-induced Lung Cancer Cell Stemness and Chemotherapy Resistance. PI: Michael Hsiao
3. (2021/01/01-2022/7/31) Ministry of Science and Technology MOST 110-2320-B-010-008-MY2. ALDOC regulates PPAR-γ signaling and serotonin to inhibit glioblastoma. PI: Yu-Chan Chang
4. (2022/01/01-2022/12/31) 111 Yen Tjing Ling Medical Foundation (CI-111-9). Aldolase A and Phospholipase D1 form synergistically to promote autophagy and DNA repair to resist alkylating agents and radiation in lung cancer. PI: Yu-Chan Chang
5. (2022/01/01-2022/12/31) Veterans General Hospitals and University System of Taiwan Joint Research Program (VGHUST111-G3-3-2). Purine biosynthesis in urothelial carcinomas and its relationship with FGFR family. PI: Yu-Chan Chang
6. (2022/07/01-2023/02/28) MOST College Student Research Program (111-2813-C-A49-111-B). Pyrimidine biosynthesis in urothelial carcinomas and its relationship with FGFR family. PI: Yu-Chan Chang
7. (2022/08/01-2025/07/31) Ministry of Science and Technology MOST 111-2314-B-A49-036-MY3. Studying on the therapeutic effect, immune infiltration response and IDH1 mutation of ALDOC/PPAR-γ signaling in combating glioblastoma. PI: Yu-Chan Chang
8. (2023/01/01-2023/12/31) 112 Yen Tjing Ling Medical Foundation (CI-112-6). Aldolase A degrades ATPase inhibitory factor and reprograms energy metabolism in cancer stem cells. PI: Yu-Chan Chang
9. (2023/01/01-2023/12/31) 112 National Yang Ming Chiao Tung University-Kaohsiung Medical University Joint Research Project, (#NYCUKMU-112-I003). Precision medicine prediction and novel strategies for third-generation EGFR -TKI resistant lung cancer patients. PI: Yu-Chan Chang
10. (2023/08/01-2026/07/31) Ministry of Science and Technology NSTC 112-2314-B-075-009-MY3. Exploring the role of B cells and tertiary lymphoid structures (TLSs) in the tumor microenvironment of cholangiocarcinoma. Co-PI: Yu-Chan Chang
11. (2023/08/01-2026/07/31) Ministry of Science and Technology NSTC 112-2314-B-075-021-MY3. Studying the influence of IDH1 hotspot mutations on cellular and tumor microenvironment in cholangiocarcinoma. Co-PI: Yu-Chan Chang
12. 112年度新進基礎培育支持方案
13. (2024/01/01-2024/12/31) 113 National Yang Ming Chiao Tung University-Kaohsiung Medical University Joint Research Project, (#NYCUKMU-113-I0023). Patient-derived organoids/xenograft model as potential therapeutic strategies for patients with Osimertinib-resistance lung cancer. PI: Yu-Chan Chang
14. (2025/01/01~2025/12/31) Veterans General Hospitals and University System of Taiwan Joint Research Program (VGHUST114-G1-8-3). Interpretation of the relationship between NRF2, ROS and ferroptosis regulated by SLC25A11. PI: Yu-Chan Chang
15. (2025/01/01~2025/12/31) 114 National Yang Ming Chiao Tung University-Cheng Hsin General Hospital Joint Research Project, (CY11406). Multi-omics integration, predictor identification and tumor microenvironment construction in advanced renal cell carcinoma. PI: Yu-Chan Chang
博士班(入學年度)
1. 郭翰錫 (113)
2. 林又妤 (114)
3. Rengasri Manikannan (114)
碩士班 (入學年度)
1. 林柏玄 (110) (111下_白金科技-優秀碩士生獎)
2. 蔡惠宇 (110)
3. 葉佳穎 (111)
4. 郭翰錫 (111)
5. 林又妤 (112)
6. 何兆璟 (113)
7. 鄭翔友 (114)
8. 趙菁禾 (114)
大學生
1. 何兆璟 (111 科技部大專生研究計畫)
(110下_白金科技-優秀學士生獎) (111上_白金科技-優秀學士生獎)
2. 鄭筱臻
IIPP student
1. Phạm Hưng Thịnh (Thomas)_Hanoi University of Pharmacy (2024/01/15-2024/03/30)
2. Phí NgọC Trâm (Jade)_Hanoi University of Pharmacy (2024/01/15-2024/03/30)
3. Veronica Kuo_University of Southern California (2024/05/13-2024/06/25)
Education
Ph. D.
Sep. 2011 to Jun. 2017
Department of Life sciences, National Defense Medical Center, Taipei, Taiwan
M.S
Sep. 2009 to Jun. 2011
Department of Dentistry, National Defense Medical Center, Taipei, Taiwan
B.S
Sep. 2005 to Jun. 2009
Department of Dental Hygiene, China Medicine University, Taichung, Taiwan
Honors and Awards
Outstanding Poster, NDMC Retreat Meeting, 2016
Highlights-Graduate Student Research in Pathology, ASIP, 2017
Outstanding Oral Presentation, NDMC Retreat Meeting, 2017
Regular Postdoctoral Scholars, Academia Sinica, 2018
Awarded Academia Sinica Postdoctoral Fellow ship, 2018.8-2020.6
Global Young Scientists Summit (GYSS), Singapore, 2019
11th HOPE meeting, Japan Society for the Promotion of Science (JSPS), 2019
Highlights-I Am an ASIP Member and This is My Science, ASIP, 2019
GRC Poster Award Competition, Genomics Research Center, Academia Sinica, 2019
科技部補助大專院校延攬特殊優秀人才補助 (MOST Young Scholar Fellowship, 2020-2022)
財團法人沈力揚教授醫學教育獎學紀念基金會-111講師級研究與進修獎助 (2022)
111學年度學院英語授課教學獎 (2023)
第十九屆榮總台灣聯合大學合作研究成果發表會壁報組競賽臨床醫學組I第三名(2023)
IJMS Young Investigator Award (2024)
台北市114年社會優秀青年(2025)
Page updated
Google Sites
Report abuse