Conference Abstracts
Oral Presentation
1. Lin BS, Cai HY, Chang YC. Overexpression of the de novo purine biosynthesis enzyme PFAS confers urothelial carcinoma proliferation and tumorigenicity via Myc positive feedback loop. 2023 The 37th Joint Annual Conference of Biomedical Science, Taipei, Taiwan (獲選大會演講)
2. Chang YC, Hsiao M. Loss-of-Function Aldolase C Hypermethylation Cause Serotonin Production in Glioblastoma. 2020 Annual Meeting at Experimental Biology. San Diego, CA, USA. (Virtual)
3. Chang YC, Hsiao M. Interactions of Aldolase A with ATPase Inhibitory Factor 1 Reprogram Energy Metabolism to Maintain Cancer Stemness. 2019 Annual Meeting at Experimental Biology. Orlando, FL, USA.
4. Chang YC, Hsiao M. Non-enzymatic Functions of Aldolase A Induce Oct4 Activation to Promote Lung Cancer Stemness. 2018 Annual Meeting at Experimental Biology. San Diego, USA, Apr. 21. to Apr. 25, 2018.
5. Chang YC, Hsiao M. Solute Carrier Family 2 Member 4 Regulates TRIM24-DDX58 Axis to Promote Head and Neck Cancer Metastasis. 2017 American society for Investigative Pathology (ASIP) Annual Meeting, Chicago, IL, USA. (Selected for Outstanding Graduate Study Performance)
6. Chang YC, Jan YH, Su CY, Hsiao M. Non-glycolytic Function of Aldolase A Promotes Lung Cancer Metastasis through Down-regulation of PLD2 Enzyme to Activate PLD1. 2015 American society for Investigative Pathology (ASIP) Annual Meeting, Mar. 28 to Apr. 1, Boston, MA, USA
7. Chang YC, Jan YH, Su CY, Hsiao M. Aldolase A Interplays PLD1/2 Activity through Its Enzyme-independent Function to Promote Lung Cancer Metastasis. 2015 The 30th Joint Annual Conference of Biomedical Science, Taipei, Taiwan
8. Chang YC, Hsiao M. Identification of ALDOA as a new Lung adenocarcinoma predict gene involve cancer. metabolism and tumor metastasis. 2013 American society for Investigative Pathology Annual Meeting, Apr. 20 to 24. Boston, MA, USA
Poster Presentation
1. Cai HY, Lin BS, Chang YC. Estrogen receptor α inhibition enhances radiosensitization of breast cancer cells. 2023 The 37th Joint Annual Conference of Biomedical Science, Taipei, Taiwan
2. Yu-Chan Chang, Michael Hsiao. The effect of Aldolase C reflects the neurotransmitter secretion and PPARγ signaling in Glioblastoma. 2022 Annual Meeting at Experimental Biology. Philadelphia, PA, USA.
3. Bo-Syuan Lin, Yu-Chan Chang. Purine biosynthesis and related enzymes play the oncogenic function in FGFR3 mutant urothelial carcinoma. 2022 Annual Meeting at Experimental Biology. Philadelphia, PA, USA.
4. Bo-Syuan Lin, Zhi-Xuan Chang, Yu-Chan Chang. V-ATPase Family Reflects Radiosensitivity and Neutralizes Tumor-Infiltrating Lymphocytes of Glioblastoma Cells. 2022 The 36th Joint Annual Conference of Biomedical Science, Taipei, Taiwan
5. Huei-Yu Cai, Zhi-Xuan Chang, Yu-Chan Chang. Aldolase A induces Phospholipase D reprogram to resist alkylating agents and radiation in lung cancer cells. 2022 The 36th Joint Annual Conference of Biomedical Science, Taipei, Taiwan
6. Chang YC, Chan MS, Hsiao M. Tumor Metastasis Specific Peptide- NIR Persistent Luminescence Nanoparticles Conjugated Application: Next-Generation Theranostic Approach. 2020 Federation of Asian Societies for Molecular Imaging (FASMI). Taipei, Taiwan.
7. Chang YC, Chen MH, Hsiao M. Regorafenib targets YAP1 to inhibit epithelial-mesenchymal transition and cancer metastasis of cholangiocarcinoma. 32nd EORTC-NCI-AACR symposium: molecular targets and cancer therapeutics. Oct 24-25, 2020 (Virtual)
8. Chen CL, Chang YC, Hsiao M. Rab GTPases Accelerates GLUT4 Translocation in Colorectal Cancer Progression by Insulin/IGF system. 2020 Annual Meeting at Experimental Biology. San Diego, CA, USA. (Virtual)
9. Chang YC, Hsiao M. Overexpression of Solute Carrier Family in Ambient Particulate Matter Exposure Fibroblasts Enhances Lung Cancer Progression. 2020 Annual Meeting at Experimental Biology. San Diego, CA, USA. (Virtual)
10. Tien CP, Chang YC, Hung SC, Hsiao M. PM2.5 Activates Sirtuin-SREBP1-PIR Axis to Induce Pulmonary Fibroblast Inflammation. 2019 Annual Meeting at Experimental Biology. Orlando, FL, USA. April 6-9, 2019
11. Tseng YW, Chang YC, Hsiao M. Translocation and Targeting of PGK1 to HTATSF1 Regulate Cancer Cell Metastatic Ability. 2019 Annual Meeting at Experimental Biology. Orlando, FL, USA. April 6-9, 2019
12. Chen CL, Chang YC, Hsiao M. Dystrophin Promotes Colorectal Carcinoma Metastasis and Exosome Secretion via Protein-Protein Interaction with Rab GTPasse 3C. 2019 Annual Meeting at Experimental Biology. Orlando, FL, USA. April 6-9, 2019
13. Chang YC, Hsiao M. V-ATPase Family Regulates Lysosomal Exocytosis and Neutralizes with Tumor-Infiltrating Lymphocytes for Glioblastoma Cells. 2019 AACR Annual meeting. Atlanta, GA, USA. March 29-April 3, 2019
14. Chang YC, Hsiao M*. Glycolysis enzyme screenings identify non-glycolytic function of aldolase A that interacts and alters F-actin dynamics to promote lung cancer metastasis. ELCC 2018 European Lung Cancer Congress, Geneva, Switzerland. April 11-14. 2018.
15. Tsai, HF, Chang YC, Hsiao M*. Aldolase A triggers Oct4 activation to acquire lung cancer stem cell phenotypes through non-enzymatic functions. United States & Canadian Academy of Pathology (USCAP) Annual Meeting, Vancouver, Canada, March 17-23, 2018
16. Chang YC, Hsiao M. Hypoxia-mediated Translational Control of Hypoxia Inducible Factor 1 Alpha through Aldolase A Feedback Regulated in Lung Carcinogenesis. 2016 Translational Control of Cancer: A New Frontier in Cancer Biology and Therapy, San Francisco, CA, USA
17. Chang YC, Hsiao M. Therapeutic Targeting of Aldolase A to Inhibit Metastatic Ability via Glycolysis-independent Mechanism in Lung Cancer. 2016 1st Presentation of Investigators, Students and Academicians annual meeting, Houston, TX, USA
18. Chang YC, Jan YH, Su CY, Hsiao M. PLD1 Rather Than PLD2 Regulates Lung Cancer Metastasis Is Dependent on Non-enzymatic Function of Aldolase A. 2015 The 23th Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan
19. Chang YC, Hsiao M. Glucose Transporter 4 Drives Head and Neck Cancer Metastasis through TRIM24 Signaling Pathway. 2016 NDMC retreat, Ilan, Taiwan
20. Chang YC, Jan YH, Yang YF, Su CY, Lai TC, Hsiao M. Aldolase A induces invasion/metastasis of lung cancer through modulating HIF1-α and is a marker for poor clinical outcome. 2014 American Association for Cancer Research Annual Meeting, San Diego, CA, USA.