It's really more about how well you know your radio and can put it's capabilities to work. The Kenwood TM-D710G transceiver at left was recently added to the ISS.
Dual Band, 50W, Bluetooth, $242
Dual Band, 50W, Echolink, $345
Dual Band, GPS, APRS, TNC, Echolink, $550
HF/VHF/UHF QRP, $570
HF/VHF/UHF/D-Star, $760