References II

[1] NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses (1998), Ghosh, May and Kopp.

[2] NF-κB Signal Transduction by IKK Complexes (2006), Li and Karin.

[3] Crosstalk in NF-κB signalling pathways (2011), Oeckinghaus, Hayden and Ghosh.

[4] Activation of IKK-α of a second, evolutionarily conserved, NF-κB signalling pathway (2001), Senftleben et al.

[5] NF-kappaΒ-inducing kinase regulates the processing of NF-kappaB2 p100 (2001), Xiao, Harhaj and Sun.

[6] NF-kappaB regulation in the immune system (2002), Li and Verma.

[7] NF-kappaB promotes survival during mitotic cell cycle arrest (2004), Mistry et al.

[8] NF-κB as a critical link between Inflammation and Cancer (2009), Karin.

[9] Control of apoptosis by Rel/NF-κB transcription factors (1999), Barkett and Gilmore.

[10] NF-κB in Neurons: Behavioral and Physiologic Roles in Nervous System Function (2006), Levenson et al.

[11] 2:a000166, Cold Spring Harb Perspect Biol (2010), Kanarek et al.

[12] Shared Principles in NF-κB Signaling, (2008), Hayden and Ghosh.

[13] From Calcium to NF-κB Signaling Pathways in Neurons, (2003), Lilienbaum and Israel.

[14] Genetic evidence for the essential role of beta-transduction repeat-containing protein in the inducible processing of NF-kappa B2/P100 (2002), Fong and Sun.

[15] Regulation of the Immune System by NF-κB and IkB, (2002), Liou.

[16] Role of the NF-κB Pathway in Lymphangiogenesis and Breast Cancer Metastasis, (2010), Flister

[17] NF-kappa B/Rel family members are physically associated phosphoproteins. (1994), Korner et al.

[18] 1:a000026, Cold Spring Harb Perspect Biol, (2009), Baltimore

[19] 2:a003350, Cold Spring Harb Perspect Biol, (2010), Wertz and Dixit

[20] 1:a001271, Cold Spring Harb Perspect Biol, (2009), Kaltschmidt and Kaltschmidt.

[21] Nuclear factor-kappa B: the enemy within (2004), Aggarwal.

[22] Nuclear Transcription Factor NF-kappa B, (2004), Aggarwal et al.

[23] http://www.bu.edu/nf-kb/gene-resources/gene-knockouts/

[24] Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture (1998), Franzoso et al.

[25] Ubiquitination of RIP Is Required for TNF-α induced NFκB Activation, (2006), Li et al.

[26] The Structure of NF-κB p50 DNA complex: a starting point for analysing the Rel family, (1995), Mueller and Harrison.

[27] The Rel/NF-κB/IκB Signal Transduction Pathway and Cancer, (2003), Gilmore.

[28] Introduction to NF-kappa B: players, pathways, perspectives, (2006), Gilmore.

[29] Ubiquitination in Signaling to and Activation of IKK, (2012), Chen.

[30] Transcriptional Factor NF-κB as a Target for Therapy in Parkinson’s disease, (2011), Flood et al.

[31] Crystal structure of NF-κB (p50)2 complexed to a high-affinity RNA aptamer, (2003), Huang et al.

[32] Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons, (2007), Mikenberg et al.

[33] Specific Recognition of Linear Ubiquitin Chains by NEMO is Important for NF-κB Activation, (2009), Rahingi et al.

[34] Stabilization of RelB Requires Multidomain Interactions with p100/p52, (2008), Fusco et al.

[35] The regulation of protein phosphorylation, (2009), Johnson.

[36] The lynphotoxin beta Receptor induces different patterns of gene expression (2002), Dejardin et al.

[37] Nuclear Factor (NF) –kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell mediated immune responses (1998), Caamao et al.

[38] Defective lymphotoxin-βeta receptor-induced NF-kappa B transcriptional activity in NIK deficient mice (2001), Yin et al.

[39] Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting (2003), Tumanov et al.

[40] Lymphotoxin beta Receptor mediates NEMO-independent NF-kappa B activation (2002), Saitoh et al.

[41] Activation and Regulation of the IkappaB Kinase in human Βcells by CD40 signalling (1999), Kosaka et al.

[42] http://www.ebi.ac.uk/interpro/entry/IPR011539

[43] Both N- and C-Terminal Domains of RelB Are Required for Full Transactivation: Role of the N-Terminal Leucine Zipper-Like Motif (1993), Dobrazanski, Ryseck and Bravo

[44] MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1 (1997), Malinin et al.

[45] The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-alpha and IKK-beta kinases (2007), Christopher et al.