Various methods were used including sweating, bloodletting, forced vomiting, and urinating to treat patients infected with the plague. Plague doctors also practiced other remedies such as putting frogs or leeches on the buboes to "rebalance the humors" as a normal routine. Plague doctors could not generally interact with the general public because of the nature of their business and the possibility of spreading the disease; they could also be subject to quarantine.
but modern cures are antibiotics such as streptomycin, gentamicin, doxycycline, or ciprofloxacin are used to treat plague. Oxygen, intravenous fluids, and respiratory support are usually also needed. People with pneumonic plague must be kept away from caregivers and other patients