occasionally and often only for certain parts of a project, for example to help to obtaine a grant, to give a signal of “ethical clearance”, or because it is meanwhile a “must have”. Once their consent for support is obtained, parent organisations often do not receive feedback whether a grant application was successful or later on the project outcome. When starting cooperation for a project, researchers and parent representatives still feel uncertain and hesitant how and when parents can be effectively involved in a research project. Both parties often feel uncomfortable in this new field of collaboration. The degree of involvement of parents is often still limited to typical tasks like dissemination or ethics rather than being extended over the entire development or life cycle. european foundthe care of newPowered by 19 Call to action We call on all stakeholders involved in neonatal research to Engage parent representatives throughout the whole study process (e.g. starting at defining the research questions and priorities to the study analysis, reporting and implementation of study results into clinical practice) Develop techniques which enable parents to contribute their opinion Provide training possibilities for parents and researchers to realise eye-to-eye partnership Deliver a framework that actively supports the involvement of parent representatives „During the last few years we have started to work more closely with parent organisations as well as individual parents in our research studies. This has been of great value for understanding what parents are interested in and what they need in order to be involved appropriately. Secondly, the parent organisations are skilled at communicating and at identifying the results from our research that will be of most interest and relevance for the 'end users', that is the patients and their families.“ Dr Jennifer Zeitlin, INSERM „ european foundation for the care of newborn infants Powered by 20 References Borup, G., Bach, K.F., Schmiegelow, M., Wallach-Kildemoes, H., Bjerrum, O.J., Westergaard, N., 2016. A Paradigm Shift Towards Patient Involvement in Medicines Development and Regulatory Science: Workshop Proceedings and Commentary. Ther. Innov. Regul. Sci. 50, 304–311. doi:10.1177/2168479015622668 Dang, A., Bn, V., 2016. Patient Advocacy and Changing Paradigm in Drug Access. Int. J. Med. Public Health 6, 154–159. doi:10.5530/ijmedph.2016.4.2 European Patients’ Academy on Therapeutic Innovation (EUPATI), 2016. 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Sci. 49, 929–939. doi:10.1177/2168479015580384 Innovative Medicines Initiative, 2016. The Innovative Medicines Initiative and patients - a partnership. Innovative Medicines Initiative, 2014. Advice to potential applicants for meaningful patient engagement in IMI projects. INVOLVE, 2012. Briefing notes for researchers: public involvement in NHS, public health and social care research. Johnson, D.S., Bush, M.T., Brandzel, S., Wernli, K.J., 2016. The patient voice in research—evolution of a role. Res. Involv. Engagem. 2. doi:10.1186/s40900-016-0020-4Regul. Rapp. Lowe, M.M., Blaser, D.A., Cone, L., Arcona, S., Ko, J., Sasane, R., Wicks, P., 2016. Increasing Patient Involvement in Drug Development. Value Health 19, 869–878. doi:10.1016/j.jval.2016.04.009 Medical Research Council, 2004. MRC Ethics Guide. Medical research involving children. NHS Health Research Authority, 2016. Public involvement in res BIOMEDICINE Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care Ha Uk Chung*, Bong Hoon Kim*, Jong Yoon Lee*, Jungyup Lee*, Zhaoqian Xie*, Erin M. Ibler, KunHyuck Lee, Anthony Banks, Ji Yoon Jeong, Jongwon Kim, Christopher Ogle, Dominic Grande, Yongjoon Yu, Hokyung Jang, Pourya Assem, Dennis Ryu, Jean Won Kwak, Myeong Namkoong, Jun Bin Park, Yechan Lee, Do Hoon Kim, Arin Ryu, Jaeseok Jeong, Kevin You, Bowen Ji, Zhuangjian Liu, Qingze Huo, Xue Feng, Yujun Deng, Yeshou Xu, Kyung-In Jang, Jeonghyun Kim, Yihui Zhang, Roozbeh Ghaffari, Casey M. Rand, Molly Schau, Aaron Hamvas, Debra E. Weese-Mayer, Yonggang Huang, Seung Min Lee, Chi Hwan Lee, Naresh R. Shanbhag, Amy S. Paller†, Shuai Xu†, John A. Rogers† INTRODUCTION: In neonatal intensive care units (NICUs), continuous monitoring of vital signs is essential, particularly in cases of severe prematurity. Current monitoring platforms require multiple hard-wired, rigid interfaces to a neonate’s fragile, underdeveloped skin and, in some cases, invasive lines inserted into their delicate arteries. These platforms and their wired interfaces pose risks for iatrogenic skin injury, create physical barriers for skin-to-skin parental/ neonate bonding, and frustrate even basic clinical tasks. Technologies that bypass these limitations and provide additional, advanced physiological monitoring capabilities would directly address an unmet clinical need for a highly vulnerable population. RATIONALE: It is now possible to fabricate wireless, battery-free vital signs monitoring systems based on ultrathin,“skin-like” measurement modules. These devices can gently and noninvasively interface onto the skin of neonates with gestational ages down to the edge of viability. Four essential advances in engineering science serve as the