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digestive CM 16 5.7 Genital organ CM 15 5.3 urinary system CM 11 3.9 Other CM 11 3.9 Respiratory system 2 0.7 Source: medical records of the newborns; *CM = Congenital Malformations. When investigating the statistical associations between the categories of congenital malformations and the neonatal variables (Table 3), p values with statistically significant differences were found for the associations between gender and genital organ CMs (p0.05. In the analysis of the frequency of the categories of congenital malformations presented by the newborns, those with compromise of the CNS constituted 21.07% of the number of malformations, whether isolated or associated. Other factors are recognized as predisposing and may increase the risk of deformities related to the closure of the neural tube, a CM of the CNS, including Diabetes Mellitus, maternal obesity, early and prenatal exposure to anticonvulsant medications, twin pregnancy, and exposure to Folic Acid antagonists.23 In an attempt to find associations between the birth of malformed NBs and the number of consultations performed during the prenatal period, one study evidenced a percentage of 62.5% of the sample that attended seven or more consultations, with a p value of 0.26.17 However, as shown in the results of this study, no statistical significance was found between the CM categories and the number of prenatal consultations, with all the p values being >0.05. With regard to licit and/or illicit drug consumption during pregnancy, it was shown that the majority of the mothers (84%) did not use any drugs, with only 12% that did.