孫德萍

• 學歷 : 台北醫學大學 醫學研究所碩士 | 國防醫學大學 生命科學博士
• 現任 : 耕莘健康管理專科學校 兼任助理教授
• 經歷 : 中研院生物醫學科學研究所/台灣小鼠診所-國家綜合小鼠表現型暨藥效分析中心 特別助理 (計畫協同主持人) | Visiting Scientist, Technology and Development Team for Mouse Phenotype Analysis, RIKEN BioResource Center, Japan |

著作發表 :

• Weng SY, Yang CY, Li CC, Sun TP, Tung SY, Yen JJ, Tsai TF, Chen CM, Chen SH, Hsiao M, Huang PH, Yang-Yen HF*. Synergism between p53 and Mcl-1 in protecting from hepatic injury, fibrosis and cancer. J Hepatol. 2011, 54(4):685-94. SCI
• Sun TP, Shieh SY*. Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress. Oncogene. 2009, 28(18):1971-81. SCI
• Ou YH, Chung PH, Hsu FF, Sun TP, Chang WY, Shieh SY*. The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1. EMBO J. 2007, 26(17):3968-80. SCI
• Ou YH, Chung PH, Sun TP, Shieh SY*. p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation. Mol Biol Cell. 2005, 16(4):1684-95. SCI
• Wei JH, Chou YF, Ou YH, Yeh YH, Tyan SW, Sun TP, Shen CY, Shieh SY*. TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68. J Biol Chem. 2005 Mar 4; 280 (9):7748-57. SCI
• Markovits J, Wang Z, Carr BI, Sun TP, Mintz P, Le Bret M, Wu CW, Wu FY*. Differential effects of two growth inhibitory K vitamin analogs on cell cycle regulating proteins in human hepatoma cells. Life Sci. 2003 May 2;72(24):2769-84. SCI
• Wu FY, Sun TP*. Vitamin K3 induces cell cycle arrest and cell death by inhibiting Cdc25 phosphatase. Eur J Cancer. 1999 Sep;35 (9):1388-93. PubMed PMID: 10658532. (*correspondence) SCI
• Markovits J, Sun TP, Juan CC, Ju GC, Wu FY*. Menadione (vitamin K3) enhances the mitogenic signal of epidermal growth factor via extracellular signal-regulated kinases. Int J Oncol. 1998 Dec;13(6):1163-70. SCI
• Ngo EO, Sun TP, Chang JY, Wang CC, Chi KH, Cheng AL, Nutter LM*. Menadione-induced DNA damage in a human tumor cell line. Biochem Pharmacol. 1991 Oct 24;42(10):1961-8. SCI
• Su WC, Sun TP, Wu FY*. The in vitro and in vivo cytotoxicity of menadione (vitamin K3) against rat transplantable hepatoma induced by 3'-methyl-4-dimethyl-aminoazobenzene. Gaoxiong Yi Xue Ke Xue Za Zhi. 1991 Sep;7(9):454-9.

專書論文

• FEM1B在DNA複製逆境下調控ATR-CHK1訊息傳遞功能探討 (博士論文)
• I.嘗試以陽離子交換樹脂層析法純化豬精漿內已知的精子活動力抑制蛋白SMI之研究; II.維生素K3對人類子宮頸癌細胞之抗癌活性及作用機轉研究 (碩士論文)

PRESENTATION:

• 臺灣地區生物學發展近況---2014年第卅屆生物夏令營 (南投立德溪頭飯店─ 紅樓1F大廳), 科技部生技醫藥國家型科技計畫資源中心暨生技類核心設施平台介紹-AM1-台灣小鼠診所-國家綜合小鼠表現型暨藥效分析中心, 孫德萍博士（中央研究院）
• 台灣小鼠診所演講 Taiwan Mouse Clinic Workshop, 2012 小鼠行為實驗在研究基因功能與藥物開發應用之研討會, Mouse behaviors in studies of gene function and drug development: Precautions and experience sharing for mouse behavioral experiments, Te-Ping Sun and Wei-Wei Chiang