1.   Farag SI, Francis MK, Gurung JM, Wai SN, Stenlund H, Francis MS*, Nadeem A* (2023). Macrophage innate immune responses delineate between defective translocon assemblies produced by Yersinia pseudotuberculosis YopD mutants. Virulence. 14(1):2249790. *co-corresponding author.

2.   Nadeem A*, Berg A, Pace H, Alam A, Toh E, Åden J, Zlatkov N, Myint SL, Persson K, Gröbner G, Sjöstedt A, Bally M, Barandun J, Uhlin BE*, Wai SN* (2022). Protein-lipid interaction at low pH induces oligomerisation of the MakA cytotoxin from Vibrio cholerae.

Elife, 11:e73439. doi: 10.7554/eLife.73439. *co-corresponding author

3.  Toh E, Baryalai P, Nadeem A, Aung KM, Chen S, Persson K, Persson JL, Uhlin BE, Wai SN. Bacterial protein MakA causes suppression of tumor cell proliferation via inhibition of PIP5K1α/Akt signalling.

Cell Death and Dis, 13:1024 ; doi.org/10.1038/s41419-022-05480-7

4.    Liu Y, Nadeem A, Sebastian S, Olsson M, Styring E， Isaksson H, Tägil M, Lidgren L, Raina DB. Bone mineral: A trojan horse for bone cancers. Efficient mitochondria targeted delivery and tumor eradication with nano hydroxyapatite containing doxorubicin.

Mater Today Bio, doi: 10.1016/j.mtbio.2022.100227.

5.    Hansen CF, Nadeem A, Schmidtchen A, van der Plas MJA (2022). Differential internalization of thrombin-derived host defense into monocytes and macrophages.

J Innate Immun, 14(5):418-432.

6.    Nadeem A*, Nagampalli R*, Eric T, Alam A, Myint SL, Heidler T, Dongre M, Zlatkov N, Pace H, Bano D, Sjöstedt A, Bally M, Uhlin BE, Wai SN and Persson K (2021). A tripartite cytolytic toxin formed by Vibrio cholerae proteins with flagellum-facilitated secretion.

Proc Natl Acad Sci USA, 118(47):e2111418118. *Equal contribution

7.    Nadeem A*, Alam T, Eric T, Myint SL, ur Rehman Z, Liu T, Bally M, Arnqvist A, Sjöstdt A, Wang H, Zhu J, Persson K, Uhlin BE, Wai SN* (2021). Phosphatidic acid-mediated binding and internalization of the V. cholerae cytotoxin MakA into host cells.

PLoS Pathog, 17(3):e1009414. *co-corresponding author

8.    Nadeem A*, Aung KM*, Ray T, Persson K, Pal A, Uhlin BE and Wai SN (2021). Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein.

Int J Cancer, 149(2):442-459. *Equal contribution

9.    Brisuda A, Ho JCS, Kandiyal PS, Ng JTY, Ambite I, Butler DSC, Hacek J, Wan MLY, Tran TH, Nadeem A, Tran TH, Hastings A, Storm P, Fortunati DL, Esmaeili P, Novotna H, Hornak J, Mu YG, Mok KH, Babjuk M and Svanborg C. (2021). Bladder cancer therapy using a conformationally fluid tumoricidal peptide complex.

Nat Commun, 12(1):3427.

10. Myint SL, Zlatkov N, Aung KM, Toh E, Sjöström A, Nadeem A, Duperthuy M, Uhlin BE, Wai SN. Ecotin and LamB in Escherichia coli influence the susceptibility to Type VI secretion-mediated interbacterial competition and killing by Vibrio cholerae (2021).

Biochim Biophys Acta Gen Subj. 1865(7):129912.

11. Corkery DP*, Nadeem A*, Aung KM, Hassan A, Liu T, Cervantes R, Lystad AH, Wang H, Persson K, Puhar P, Simonsen A, Uhlin BE, Wai SN and Wu YW. (2020). The Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy.

J Cell Sci, 134(5):jcs252015 *Equal contribution

12. Joshi B, Singh B, Nadeem A, Askarian F, Wai SN, Johannessen M and Hegstad K. (2020). Transcriptome profiling of Staphylococcus aureus associated membrane-derived vesicles reveals presence of small RNA-cargo.

Front Mol Biosci, 7:566207.

13. Ahmad I, Karah N, Nadeem A, Wai SN, Uhlin BE (2019). Analysis of colony phase variation switch in Acinetobacter baumannii clinical isolates.

PLoS One. 4;14(1):e0210082. doi: 10.1371/journal.pone.0210082.

14. Nadeem A, Ho JCS, Tran TH, Paul S, Granqvist V, Despretz N and Svanborg C. (2019). Beta-sheet-specific interactions with heat shock proteins define a mechanism of delayed tumor cell death in response to HAMLET.

J Mol Biol, 431, 2612–2627.

15. Butler DSC, Ambite I, Nagy K, Cafaro C, Ahmed A, Nadeem A, Filenko N, Tran TH, Andersson KE, Wullt B, Puthia M, Svanborg C (2018). Neuroepithelial control of mucosal inflammation in acute cystitis.

Sci Rep, 2018 Jul 20;8(1):11015.

REVIEW PAPERS, EDITORIAL & BOOK CHAPTER

1. Schmidtchen A, Mirza H, van der Plas MJA, Nadeem A and Puthia M. Editorial: Methods and applications in inflammation pharmacology (2022). Front Pharmacol, doi.org/10.3389/fphar.2022.1108263.

2. Zlatkov N, Nadeem A, Uhlin BE, Wai SN. Eco-Evolutionary Feedbacks Mediated by Bacterial Membrane Vesicles (2020). FEMS Microbiol Rev, 45(2):fuaa047.

3. Nadeem A, Oscarsson J, Wai SN. Delivery of virulence factors by bacterial membrane vesicles to mammalian host cells (2020). Bacterial Membrane Vesicles. p 131-158. ISBN: 978-3-030-36330-7.

PATENTS 

1.  Nadeem A, Svanborg C and Ho JCS (2020). US Patent App. 16/612,272

2. Svanborg C, Nadeem A, Mok KH and Ho JCS (2018). Therapeutically active complexes. International Publication Number: WO2018/116165 A3.

3.   Wai SN, Uhlin BE, Nadeem A, Persson K (2019). Vibrio cholerae protein for use against cancer. PCT/SE2020/050968