Search this site
Embedded Files
Cai lab
  • Home
  • Background
  • Research
  • Group
  • Publications
  • Talks
Cai lab
  • Home
  • Background
  • Research
  • Group
  • Publications
  • Talks
  • More
    • Home
    • Background
    • Research
    • Group
    • Publications
    • Talks
NatureNewsViews2025.pdf

Cai N. Sex differences in depression revealed by large genetics study. Nature 2025 (News and Views)

MedRxivCE2025.pdf

Rietkerk J., ...Cai N.^, Genetic risk effects on psychiatric disorders act in sets, medRxiv 2025

Supplementary Text

Tweetorial by Na

Github 

BioRxiv2025_BayesRVAT.pdf

Nappi A., Cai N., Casale F. P. Bayesian Aggregation of Multiple Annotations Enhances Rare Variant Association Testing, BioRxiv 2025 

Supplementary Text

MolPsych2024.pdf

Cai N.*, Verhulst B.*, et al.  Assessment and ascertainment in psychiatric molecular genetics: challenges and opportunities for cross-disorder research, Mol Psych 2024

(Review)

BioRxiv2024_mtDNAhet.pdf

Wengert S., ... Heinig M.*, Cai N.*^ "Tissue-specific apparent mtDNA heteroplasmy and its relationship with ageing and mtDNA gene expression", BioRxiv 2024

Supplementary Text

Tweetorial by Simon

Github

BioRxiv2024_mtDNAeQTL.pdf

Giannoulis X., ... Cai N. ^ Interplay between mitochondrial and nuclear DNA in gene expression regulation, BioRxiv 2024

Supplementary Text

Tweetorial by Xenofon

Github

ChangBiorxiv2024.pdf

Chang S.*^, Fermani F.*, ... Deussing J., Cai N.^ Molecular and neural mechanisms of behavioural integration in the extended-amygdala, BioRxiv 2024

Supplementary Text

Github

BiolPsych2024.pdf

Huang L., ... Cai N.^, Polygenic Analyses Show Important Differences Between Major Depressive Disorder Symptoms Measured Using Various Instruments, Biological Psychiatry 2024


Supplementary Text


Summary Statistics


Tweets by @Lianyun_Huang


Github

NatGen2023.pdf

Dahl A.*^,... Cai N.*^ Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder, Nature Genetics 2023


Supplementary Text 


Summary Statistics 


PGS Catalogue


Github


SciAdv2022.pdf

Chang S. et al, Tripartite extended amygdala-basal ganglia CRH circuit drives arousal and avoidance behaviour, Science Advances 2022

Supplementary Text

Tweetorial by @Simon_CEChang

NatGenNewsViews2022.pdf

Schork A.*, Peterson R.E.*, Dahl A.*, Cai N.*, Kendler K.S., Indirect paths from genetics to education, Nature Genetics 2022 (News and Views)

NatMed2021.pdf

Cai N.*, Gomez-Duran A.*, et al, Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases, Nature Medicine 2021

Supplementary Text

Tweetorial

MolHumGen2020.pdf

Cai N.^, Choi K., Fried E.. Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies, Human Molecular Genetics 2020 (Review)

Tweetorial

Tweetorial by @EikoFried


NatGen2020.pdf

Cai N.^, et al, Minimal phenotyping yields genome-wide association signals of low specificity for major depression, Nature Genetics 2020

Supplementary Text

Summary statistics

Tweetorial

Related talk: CGSI2019

AJP2018.pdf

Peterson R.E.*, Cai N.*, et al, Molecular genetic analysis subdivided by adversity exposure suggests etiologic heterogeneity in major depression, American Journal of Psychiatry 2018

Supplementary Text


JAMAPsych2017.pdf

Peterson R.E.*, Cai N.*, et al, The genetic architecture of major depressive disorder in Han Chinese women, JAMA Psychiatry 2017

Supplementary Text

CurrBio2015b.pdf

Cai N., et al, Genetic control over mtDNA and its relationship to major depressive disorder, Current Biology 2015

Supplementary Text

Summary statistics


CurrBio2015a.pdf

Cai N.*, Chang S.*, Li Y.*, et al., Molecular signatures of major depression, Current Biology 2015

Supplementary Text




Nature2015.pdf

Cai N.*, Bigdeli T.B.*, Kretzschmar W.W.*, Li Y.*, et al, Sparse whole-genome sequencing identifies two loci for major depressive disorder, Nature 2015

Supplementary Text

Summary statistics

Nature News and Views

Lab members are shown in bold; *means equal contributions, ^means corresponding authorship.

Only (joint) first/last author papers of  lab members are featured on this page, for my full publication list please see Google Scholar or my CV

Google Sites
Report abuse
Page details
Page updated
Google Sites
Report abuse