Cai Lab 

Cai lab is based in the Department of Biosystems Science and Engineering (D-BSSE) in ETH Zürich and the Basel Research Centre for Child Health (BRCCH).

We are quantitative geneticists working on methods and their applications to understanding the nature of complex traits and diseases, with a special focus on psychiatric disorders like major depressive disorder (MDD). Our ongoing research focuses on 1) maximizing and verifying the utility of data from different sources for genetic investigations into complex traits and diseases using deep learning and statistical approaches, 2) identifying the molecular underpinnings of complex traits and diseases (including their heterogeneity) using genetic effects on bulk and molecular data, and 3)  learning how environmental or genetic perturbations may reveal regulatory networks that are relevant to complex traits and diseases.