Highlighted publications:
Li J, Rahmani H, Abbasi Yeganeh F, Rastegarpouyani H, Taylor DW, Wood NB, Previs MJ, Iwamoto H, Taylor KA. Structure of the Flight Muscle Thick Filament from the Bumble Bee, Bombus ignitus, at 6 Å Resolution. Int J Mol Sci. 2022 Dec 26;24(1):377.
Previs MJ. Calcium activation through thick and thin? J Gen Physiol. 2023 Jan 2;155(1):e202213265.
Riley LA, Zhang X, Douglas CM, Mijares JM, Hammers DW, Wolff CA, Wood NB, Olafson HR, Du P, Labeit S, Previs MJ, Wang ET, Esser KA. The skeletal muscle circadian clock regulates titin splicing through RBM20. Elife. 2022 Sep 1;11:e76478.
Wood NB, Kelly CM, O'Leary TS, Martin JL, Previs MJ. Cardiac Myosin Filaments are Maintained by Stochastic Protein Replacement. Mol Cell Proteomics. 2022 Oct;21(10):100274.
Previs MJ, O'Leary TS, Morley MP, Palmer BM, LeWinter M, Yob JM, Pagani FD, Petucci C, Kim MS, Margulies KB, Arany Z, Kelly DP, Day SM. Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy. Circ Heart Fail. 2022 Jun;15(6):e009521.
Tsan YC, DePalma SJ, Zhao YT, Capilnasiu A, Wu YW, Elder B, Panse I, Ufford K, Matera DL, Friedline S, O'Leary TS, Wubshet N, Ho KKY, Previs MJ, Nordsletten D, Isom LL, Baker BM, Liu AP, Helms AS. Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform. Nat Commun. 2021 Oct 25;12(1):6167.
Rahmanseresht S, Lee KH, O'Leary TS, McNamara JW, Sadayappan S, Robbins J, Warshaw DM, Craig R, Previs MJ. The N terminus of myosin-binding protein C extends toward actin filaments in intact cardiac muscle. J Gen Physiol. 2021 Mar 1;153(3):e202012726.
Daurio NA, Zhou H, Chen Y, Sheth PR, Imbriglio JE, McLaren DG, Tawa P, Rachdaoui N, Previs MJ, Kasumov T, O'Neil J, Previs SF. Examining Targeted Protein Degradation from Physiological and Analytical Perspectives: Enabling Translation between Cells and Subjects. ACS Chem Biol. 2020 Oct 16;15(10):2623-2635.
Daneshparvar N, Taylor DW, O'Leary TS, Rahmani H, Abbasiyeganeh F, Previs MJ, Taylor KA. CryoEM structure of Drosophila flight muscle thick filaments at 7 Å resolution. Life Sci Alliance. 2020 Jul 27;3(8):e202000823.
Helms AS, Tang VT, O'Leary TS, Friedline S, Wauchope M, Arora A, Wasserman AH, Smith ED, Lee LM, Wen XW, Shavit JA, Liu AP, Previs MJ, Day SM. Effects of MYBPC3 loss-of-function mutations preceding hypertrophic cardiomyopathy. JCI Insight. 2020 Jan 30;5(2):e133782.
Li A, Nelson SR, Rahmanseresht S, Braet F, Cornachione AS, Previs SB, O'Leary TS, McNamara JW, Rassier DE, Sadayappan S, Previs MJ, Warshaw DM. Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21882-21892.
Inchingolo AV, Previs SB, Previs MJ, Warshaw DM, Kad NM. Revealing the mechanism of how cardiac myosin-binding protein C N-terminal fragments sensitize thin filaments for myosin binding. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6828-6835.
O'Leary TS, Snyder J, Sadayappan S, Day SM, Previs MJ. MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy. J Mol Cell Cardiol. 2019 Feb;127:165-173.
All publications: https://www.ncbi.nlm.nih.gov/myncbi/1JyoAvnftCNQh/bibliography/public/
