Embedded Files
[25]
Discovery of Novel GPR119 Agonists with Improved Kinetic Solubility and Drug-like Properties for Type 2 Diabetes Treatment
Min, J.†; Kim, J.†; Moon, K.†; Kim, M.; Suh, D.-H.; Lee, J.; Ko, M.; Lee, J.; Han, Y.; Jang, I.; Park, G. T.; Yang, H.-M.; Min, J.; Lee, S.; Rakshit, A.; Han, S. B.; Singh, P.; Lee, C.; Kim, I. S.*
J. Med. Chem. 2026, in press.
[24]
Discovery of acridone analogs as novel entry inhibitors targeting e protein of dengue virus
Lim, D.; Lee, C.; Kim, J.; Kim, H.; Moon, K.; Singh, P.; Rakshit, A.; Min, S.; Kim, Y. J.; Kim, J.-K.; Kim, L. T. A.; Das, S.; Kim, K. K.; Lee, H.-R.; Kim, I. S.*
Bioorg. Chem. 2026, 181, 110314.
[23]
Discovery of novel ENPP1 inhibitors with benzotriazole core for cancer immunotherapy
Choi, J.; Lee, S.; Park, Y.-Y.; Kim, J.; Kim, H.; Moon, K.; Park, S.; Yoo, E. K.; Min, C. W.; Lee, H. W.; Park, H.-J.; Singh, P.; Kim, S.; Park, C. S.; Kim, I. S.*
Eur. J. Med. Chem. 2026, 307, 118666.
[22]
Synthesis and Translational Assessment of Trinucleotide 5′-Cap Analogs for Messenger Ribonucleic Acid-Based Therapeutics
Kim, J.†; Moon, K.†; Kim, J.; Park, S.-J.; Kim, N.; Jung, Y.; Lee, Y.; Lee, K.; Yoo, W.; Kim, J. H.; Kim, B.-W.; Kim, D.; Park, H.-J.; Lee, J.; Singh, P.; Kim, I. S.*
J. Med. Chem. 2026, 69, 5811–5827.
[21]
Vinylene Carbonate as an Ethylene Equivalent for the Synthesis of 1,2-Bis(indolyl)ethenes and Benzo[α]carbazoles
Hyun, J.†; Moon, K.†; Jeong, J.; Singh, P.; Rakshit, A.; Kim, I. S.*
Org. Lett. 2026, 28, 1463–1468.
[20]
Discovery of Novel Triple A1/A2A/A2B Adenosine Receptor Antagonists for Cancer Immunotherapy
Jun, S.; Lee, Y.; Lee, H.; Jang, S. Y.; Ahn, Y. G.; Kim, J.; Park, H.-J.; Singh, P.; Moon, K.*; Kim, I. S.*
J. Med. Chem. 2025, 68, 23117–23139.
[19]
C3-Heteroarylation of Indoles via Cu(II)-Catalyzed Aminocupration and Subsequent Nucleophilic Addition of o-Alkynylanilines
Rakshit, A.†; Moon, K.†; Singh, P.; Kim, I. S.*
J. Org. Chem. 2025, 90, 3444–3453.
[18]
Discovery of 1,4-Disubstituted Cyclohexene Analogues as Selective GPR119 Agonists for the Treatment of Type 2 Diabetes
La, H.; Kim, J.; Kim, D.-H.; Kim, S.-H.; Singh, P.; Nam, G.; Moon, K.*; Kim, I.*; Kim, I. S.*
J. Med. Chem. 2025, 68, 4619–4634.
[17]
Photoredox-Catalyzed Minisci-Type Acylation of Heterocyclic C–H Bonds with Amino Acid-Tethered Dihydropyridines
Yang, H.; Shin, H.; Lee, Y.; Lim, D.; Kwon, N. Y.; Rakshit, A.; Singh, P.; Kim, H. J.; Moon, K.*; Kim, I. S.*
Adv. Synth. Catal. 2025, 367, e202401394.
[16]
Synthesis of Quinoline–Indole Hybrids through Cu(II)-Catalyzed Amination and Annulation between N-Oxides and o-Alkynylanilines
Rakshit, A.†; Moon, K.†; Singh, P.; Park, J. S.; Kim, I. S.*
Org. Lett. 2024, 26, 11218–11223.
[15]
Thione-Directed C–H Amidation of Chromone Analogues with Dioxazolones Under Rh(III) Catalysis
Min, J.; Park. K.; Moon, K.; Kim, H. S.; Singh, P.; Kim, I. S.*
Org. Lett. 2024, 26, 9157–9161.
[14]
The stimulatory effect of HI 129, a novel indole derivative, on glucose-induced insulin secretion
Chau, G. C.; Lim, J. E.; Moon, K.; Kim, I. S.*; Um, S. H.*
Biochem. Pharmacol. 2024, 230, 116558.
[13]
Redox-Neutral Vicarious-Type Nucleophilic Amination of Heterocyclic N-Oxides with Organic Azides
Min, J.; Min, S.; Chung, E.; Moon, K.; Kim, H. S.; Jeong, T.; Rakshit, A.; Singh, P.; Park, J. S.; Kim, I. S.*
Adv. Synth. Catal. 2024, 366, 4158–4162.
[12]
Discovery of 2,6-Naphthyridine Analogues as Selective FGFR4 Inhibitors for Hepatocellular Carcinoma
Oh, H.; Kim, J.; Jung, S. H.; Ha, T. H.; Ahn, Y. G.; Nam, G.; Moon, K.; Singh, P.; Kim, I. S.*
J. Med. Chem. 2024, 67, 8445–8459.
[11]
Development of novel indole-quinoline hybridic molecules targeting bacterial proton motive force
Seo, J.; Kim, J.-H.; Ko, N.; Kim, J.; Moon, K.; Kim, I. S.*; Lee, W.*
J. Appl. Microbiol. 2024, 135, lxae104.
[10]
Manufacturing Process Development of Tegoprazan as a Potassium-Competitive Acid Blocker (P-CAB)
Kweon, J.-H.; Shin, H.; Lee, M. K.; Lee, S. A.; Singh, P.; Moon, K.*; Kim, I. S.*
Org. Process Res. Dev. 2024, 28, 1159–1169.
[9]
Tandem annulation and dipolar cycloaddition of azomethine imines in catalytic C(sp2)–H functionalization
Mishra, N. K.; Rakshit, A.; Moon, K.; Singh, P.; Kim, I. S.*
Bull. Korean Chem. Soc. 2024, 45, 131–144.
[8]
Sulfur-Directed α-C(sp3)–H Amidation of Pyrrolidines with Dioxazolones Under Rhodium Catalysis
Singh, P.; Min, J.; Min, S.; Moon, K.; Kim, H. S.; Kim, I. S.*
Org. Lett. 2024, 26, 57–61.
[7]
Catalyst-Controlled C–H Allylation and Annulation of 2‑Aryl Quinazolinones with 2‑Methylidene Cyclic Carbonate
Ko, N.; Min, S.; Moon, K.; Shin, H.; Kwon, N. Y.; Mishra, N. K.; Rakshit, A.; Singh, P.; Kim, I. S.*
J. Org. Chem. 2023, 88, 13315–13326.
[6]
Design and synthesis of 4th generation EGFR inhibitors against human triple (Del19/T790M/C797S) mutation
Jeon, J.; Jang, S. Y.; Kwak, E. J.; Lee, S. H.; Byun, J.-Y.; Kim, Y.-Y.; Ahn, Y. G.; Singh, P.; Moon, K.; Kim, I. S.*
Eur. J. Med. Chem. 2023, 261, 115840.
[5]
Synthesis of 2-Formyl Carbazoles via Tandem Reaction of Indolyl Nitrones with 2-Methylidene Cyclic Carbonate
Min, S.; Kim, T.; Jeong, T.; Yang, J.; Oh, Y.; Moon, K.; Rakshit, A.; Kim, I. S.*
Org. Lett. 2023, 25, 4298–4302.
[4]
Rhodium(III)-Catalyzed Conjugate Addition of β‑CF3‑Enones with Quinoline N‑Oxides
Ko, N.; Min, J.; Moon, J.; Ismail, N. F.; Moon, K.; Singh, P.; Mishra, N. K.; Lee, W.; Kim, I. S.*
J. Org. Chem. 2023, 88, 602–612.
[3]
Methylene Thiazolidinediones as Alkylation Reagents in Catalytic C–H Functionalization: Rapid Access to Glitazones
Byun, Y.†; Moon, K.†; Park, J.; Ghosh, P.; Mishra, N. K.; Kim, I. S.*
Org. Lett. 2022, 24, 8578–8583.
[2]
Synthesis of π‑Extended Heterocycles via Rh(III)-Catalyzed Oxidative Annulation of 5‑Aryl Pyrazinones with Alkynes
Oh, H.; Byun, H. W.; Moon, K.; Kim, S.; Ghosh, P.; An, W.; Kwak, J. H.; Park, J. S.; Mishra, N. K.; Kim, I. S.*
J. Org. Chem. 2021, 86, 16349–16360.
[1]
Synthesis of (2H)-Indazoles and Dihydrocinnolinones through Annulation of Azobenzenes with Vinylene Carbonate under Rh(III) Catalysis
Park, M. S.†; Moon, K.†; Oh, H.; Lee, J. Y.; Ghosh, P.; Kang, J. Y.; Park, J. S.; Mishra, N. K.; Kim, I. S.*
Org. Lett. 2021, 23, 5518–5522.
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