연구실적 - Publications

Selected Publications 

All peer-reviwed Publications 

1)      Kim H, Kim H,  and Yoon HG, et al Investigation of the mechanism of p300 stability regulation mediated by protein phosphatase PPM1D in hepatic stellate cells. (Summited at BBRC, Corresponding Author)

2)     Kim H,  Yoo JY  Characterizing the Association between GOLM1 and MASH-related Fibrosis through Multi-cohort Transcriptomic Analysis and AI-assisted Validation. J Korean Health & Fundamental Med Sci, 2026 Jun 19(1), 143-152.

3)     Jung JS*, Kim H*, Yoo JY, et. al. Identification of Urinary MMP9 as a Potential Non-Invasive Biomarker for Endometrial Cancer through Multi-Omics Analysis with Machine Learning–Assisted Validation Biomed. Sci. Lett 2026;32(1):73-87

4)     Kim H*, Hwang SY*, Lee SH, Yoon HG, et al AI-Driven Discovery of Bronopol for the Treatment of Pulmonary Fibrosis via Inhibition of Fibroblast Activation. Life sciences. 2026 Jun 11:124535

5)      Kim H, Lee SH, JH Kwon, Yoon HG, et al PPM1M Suppresses EMT by Regulating p300 Protein Stability in Renal Proximal Tubule Cells. Biochem Biophys Res Commun 824, 30 July 2026, 153959

6)     Byun S, Kim H , Yoon HG, et al. Deficiency of GCN5 Exacerbates Pulmonary Fibrosis by Disrupting the LKB1–AMPK Pathway. Cell Communication and Signaling 2026 Apr 20;24(1):327. (Co-Author)

7)      Kim H, Yu S, Yoo JY.    Integrative Multi-Omics Analysis Reveals CDKN2A as a Potential Diagnostic and Prognostic Biomarker in Cervical Cancer. J Korean Health & Fundamental Med Sci 2025 Dec;18(2):75-84

8)     Byun S*, Kim H *, Yoon HG, et. al. Deubiquitinase USP2 Promotes Hepatic Stellate Cell Activation via p300 Stabilization. FEBS letters 2026 May;600(9):1318-1329. (Co-first)

9)     Kim H, Kwon JH, Park SY, Lee SY, Yoon HG, et al. Loss of PCAF in proximal tubular cells exacerbates renal fibrosis by promoting partial epithelial-to-mesenchymal transition. Experimental & molecular medicine 2025 Sep;57(9):2010-2021.

10)  Kim H, Chun KH, Yoon HG, Yoo JY, et al In silico analysis highlights elevation of epithelial-to-mesenchymal transition characteristics in non-responding lupus nephritis patients. Lupus 2025 Oct;34(11):1147-1157.

11)   Kim H, Park SY, Lee SY, Kwon JH, Yoon HG, et al. Proximal tubular cell-specific p300 mediates the endothelial to mesenchymal transition to promote renal fibrosis. EMBO Molecular Medicine 2025 Jul;17(7):1575-1598

12)  Kim H, Yu S, Yoo JY The Potential of CNTFR as a Biomarker for Urine-Based Non-Invasive Diagnosis in Prostate Cancer.  Lab Med 2025 Nov 22;56(6):663-669

13)  Kim H,  Yoo JY Diagnostic Potential of Urinary ACP1 in Bladder Cancer Revealed by Integrative Omics Analysis. KJCLS 2025;57:259-270

14)  Kim H,  Yoo JY  Model-Specific Responses of Blood Urea Nitrogen and Serum Creatinine in Rodent Renal Fibrosis Models. J Korean Health & Fundamental Med Sci 2025 June;18(1) 59-67

15)  Kim H, Yu S, Yoo JY Recent Trends in the Use of Rodent Models in Kidney Fibrosis Research. Biomed. Sci. Lett. 2025;31(2):89-98

16)  Kim H, Yoon HG, Yoo JY Plumbagin ameliorates renal fibrosis by suppressing epithelial-mesenchymal transition. Biochem Biophys Res Commun 2025 Mar 1:750:151325

17)   Kim H, Kim HS, Lee SH, Yoon HG et al. Deubiquitinase inhibitor bAP-15 suppresses renal fibrosis via inhibition of p300-mediated epithelial to mesenchymal transition. Biochem Biophys Res Commun 2024 31:741:151095

18)  Kim H, Park SY, Lee SY, Kwon JH, Byun S, Kim MJ, et al. Therapeutic effects of selective p300 histone acetyl-transferase inhibitor on liver fibrosis. BMB Rep 2023 Feb;56(2):114-119.

19)  Kim H, Jang S, Lee SY, Kwon JH, Byun S, Yoo JY, et al. JMJD4 promotes tumor progression via inhibition of the PDCD5–TP53 pathway. BMB Rep 2025 Feb;58(2):64-69

20) Lee SY, Park SY, Lee SH, Kim H, Kwon JH, Yoo JY, et al. The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis. Exp Mol Med 2023;55:1795-805.

21)  Lee SY, Park SY, Lee GE, Kim H, Kwon JH, Kim MJ, et al. Aucuparin Suppresses Bleomycin-Induced Pulmonary Fibrosis Via Anti-Inflammatory Activity. J Med Food 2021;24:151-60.