2024
Shunsuke Kotani, Toshifumi Asano, Sachie Arae, Masaharu Sugiura, Makoto Nakajima
Mechanistic Investigations of Chiral Lithium Binaphtholate Catalysis for Asymmetric Aldol–Tishchenko Reaction of α-Fluoroarylketones.
J. Org. Chem. 2024, 89, 17101−17114.
Kensuke Motomura, Erika Ueda, Alex Boateng, Masaharu Sugiura, Keiichi Kadoyama, Natsuko Hitora-Imamura, Yuki Kurauchi, Hiroshi Katsuki, Takahiro Seki
Identification of a novel aromatic-turmerone analog that activates chaperone-mediated autophagy through the persistent activation of p38.
Front. Cell Dev. Biol. 2024, 12, 1418296.
杉浦正晴
四塩化チタンを用いるアルドール縮合の開発と展開
有機合成化学協会誌 2024, 82, 570–580.
Salma M. Hefny, Tarek F. El-Moselhy, Nabaweya El-Din, Simone Giovannuzzi, Thamer Bin Traiki, Mansoor-Ali Vaali-Mohammed, Ahmed M. El-Dessouki, Koki Yamaguchi, Masaharu Sugiura, Moataz A. Shaldam, Claudiu T. Supuran, Maha-Hamadien Abdulla, Wagdy M. Eldehna, and Haytham O. Tawfik
Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR-2 as Potential Agents for Solid Tumors: X-ray, In Vitro, In Vivo, and In Silico Investigations of Coumarin-Based Thiazoles.
J. Med. Chem. 2024, 67, 7406–7430.
Tomofumi Nakamura, Mayu Okumura, Nobutoki Takamune, Tatsunori Hirotsu, Masaharu Sugiura, Junichiro Yasunaga, Hirotomo Nakata
Conversion of Raltegravir Carrying a 1,3,4-Oxadiazole Ring to a Hydrolysis Product upon pH Changes Decreases Its Antiviral Activity.
PNAS Nexus 2024, 3(1), 446.
2023
Natsuho Harada, Toshifumi Asano, Masaharu Sugiura, Shunsuke Kotani, Makoto Nakajima
Lithium Binaphtholate-Catalyzed Asymmetric Michael Reaction of Acrylamides.
Chem. Pharm. Bull. 2023, 71, 792–797.
Mahmoud G. Abo Al-Hamd, Haytham O. Tawfik, Omeima Abdullah, Koki Yamaguchi, Masaharu Sugiura, Ahmed B. M. Mehany, Mervat H. El-Hamamsy, Tarek F. El-Moselhy
Recruitment of Hexahydroquinoline as Anticancer Scaffold Targeting Inhibition of Wild and Mutants EGFR (EGFRWT, EGFRT790M, and EGFRL858R)
J. Enz. Inhibit. Med. Chem. 2023, 38, 2241674.
Alex Boateng, Masayuki Amano, Masaharu Sugiura
Synthesis of Selenoesters via Aldol Condensation and/or Conjugate Reduction and Their Antiviral Activities.
ACS Omega 2023, 8, 1369–1374.
2022
Shaldam Moataz, Tawfik Haytham, Elmansi Heba, Belal Fathalla, Yamaguchi Koki, Sugiura Masaharu, Magdy Galal
Synthesis, crystallographic, DNA binding, and molecular docking/dynamic studies of a privileged chalcone-sulfonamide hybrid scaffold as a promising anticancer agent.
J. Biomol. Struct. Dyn. 2022, 41, 8876–8890.
Makoto Nakajima, Shunsuke Kotani, Masaharu Sugiura
Enantioselective Epoxide Opening.
Org. React. 2022, 110, 655–902.
2021
Yuria Hori, Reiho Tsutsumi, Kento Nasu, Alex Boateng, Yasuhiko Ashikari, Masaharu Sugiura, Makoto Nakajima, Yuki Kurauchi, Akinori Hisatsune, Hiroshi Katsuki, Takahiro Seki
Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities.
Cells 2021, 10, 1090.
2020
Alex Boateng, Tokifumi Harada, Yasuhiko Ashikari, Makoto Nakajima, Masaharu Sugiura
Synthesis of conjugated multiunsaturated thioesters via one-pot TiCl4-promoted aldol condensation
Tetrahedron Lett. 2020, 61, 152280.
Takuto Yoshimitsu, Yukinobu Kuboyama, Sari Nishiguchi, Makoto Nakajima, Masaharu Sugiura
O-Monoacyltartaric Acid/(Thio)urea Cooperative Organocatalysis for Enantioselective Conjugate Addition of Boronic Acid.
Org. Lett. 2020, 22, 3780–3784.
Masaharu Sugiura, Shunsuke Kotani, Makoto Nakajima
Catalysis by Silicon Species (Chapter 11)
In Catalysis with Earth-abundant Elements, Uwe Schneider and Stepen Thomas Eds., Royal Society of Chemistry, 2020, pp309–333.
2019
Masaharu Sugiura, Yasuhiko Ashikari, Yuka Takahashi, Koki Yamaguchi, Shunsuke Kotani, Makoto Nakajima
Lewis Base-Catalyzed Enantioselective Conjugate Reduction of β,β-Disubstituted α,β-Unsaturated Ketones with Trichlorosilane: E/Z-Isomerization, Regioselectivity, and Synthetic Applications.
J. Org. Chem. 2019, 84, 11458–11473.
Yuki Hashimoto, Chiaki Michimuko, Koki Yamaguchi, Makoto Nakajima, Sugiura Masaharu
Selective Monoacylation of Diols and Asymmetric Desymmetrization of Dialkyl meso-Tartrates Using 2-Pyridyl Esters as Acylating Agents and Metal Carboxylates as Catalysts.
J. Org. Chem. 2019, 84, 9313–9321.
2018
Shunsuke Kotani, Yusaku Yoshiwara, Masamichi Ogasawara, Masaharu Sugiura, Makoto Nakajima
Catalytic Enantioselective Aldol Reactions of Unprotected Carboxylic Acids under Phosphine Oxide Catalysis.
Angew. Chem. Int. Ed. 2018, 57, 15877–15881.
杉浦正晴
Ｏ‐モノアシル酒石酸触媒によるホウ素化合物の活性化
有機合成化学協会誌 2018, 76, 596–603.