Publications

Representative publications are featured below.  For a full bibliography, see Google Scholar

Guanidine aptamers are present in vertebrate RNAs associated with calcium signaling and neuromuscular function

K Kavita, A Narunsky, JJ Mohsen, I Mahadeshwar, MG Mohsen, YS Chang, RR Breaker

Nat. Commun. 2025, 16, 7362. DOI: 10.1038/s41467-025-62815-6

Prospects for Riboswitches in Drug Development

MG Mohsen, RR Breaker

In RNA as a Drug Target: The Next Frontier for Medicinal Chemistry, Methods and Principles in Medicinal Chemistry 2024, 203-226. DOI: 10.1002/9783527840458.ch8

Engineered Branaplam Aptamers Exploit Structural Elements from Natural Riboswitches

MG Mohsen, MK Midy, A Balaji, RR Breaker

ACS Chem. Biol. 2024, 19, 1447-1452. DOI: 10.1021/acschembio.4c00358

Pervasive transcriptome interactions of protein-targeted drugs

L Fang, WA Velema, Y Lee, L Xiao, MG Mohsen, AM Kietrys, ET Kool

Nat. Chem. 2023, 15, 1374-1383. DOI: 10.1038/s41557-023-01309-8

In vitro Selection and in vivo Testing of Riboswitch-inspired Aptamers

MG Mohsen, RR Breaker

Bio. Protoc. 2023, 13. DOI: 10.21769/BioProtoc.4775

Exploiting natural riboswitches for aptamer engineering and validation

MG Mohsen, MK Midy, A Balaji, RR Breaker

Nucleic Acids Res. 2023, 51, 966-981. DOI: 10.1093/nar/gkac1218

Polymerase synthesis of four-base DNA from two stable dimeric nucleotides

MG Mohsen*, D Ji*, ET Kool (*co-first authorship)

Nucleic Acids Res. 2019, 47, 9495-9501. DOI: 10.1093/nar/gkz741

Polymerase-amplified release of ATP (POLARA) for detecting single nucleotide variants in RNA and DNA

MG Mohsen, D Ji, ET Kool

Chem. Sci. 2019, 10, 3264-3270. DOI: 10.1039/C8SC03901A

The Discovery of Rolling Circle Amplification and Rolling Circle Transcription

MG Mohsen, ET Kool

Acc. Chem. Res. 2016, 49, 2540-2550. DOI: 10.1021/acs.accounts.6b00417